Structure-based prediction of HDAC6 substrates validated by enzymatic assay reveals determinants of promiscuity and detects new potential substrates

por Varga, Julia K., Diffley, Kelsey, Welker Leng, Katherine R., Fierke, Carol A., Schueler-Furman, Ora
Publicado 2022

A CRISPR screen identifies MAPK7 as a target for combination with MEK inhibition in KRAS mutant NSCLC

por Dompe, Nicholas, Klijn, Christiaan, Watson, Sara A., Leng, Katherine, Port, Jenna, Cuellar, Trinna, Watanabe, Colin, Haley, Benjamin, Neve, Richard, Evangelista, Marie, Stokoe, David
Publicado 2018

BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program

por Kim, Dae-Hwan, Sun, Duanchen, Storck, William K., Welker Leng, Katherine, Jenkins, Chelsea, Coleman, Daniel J., Sampson, David, Guan, Xiangnan, Kumaraswamy, Anbarasu, Rodansky, Eva S., Urrutia, Joshua A., Schwartzman, Jacob A., Zhang, Chao, Beltran, Himisha, Labrecque, Mark P., Morrissey, Colm, Lucas, Jared M., Coleman, Ilsa M., Nelson, Peter S., Corey, Eva, Handelman, Samuel K., Sexton, Jonathan Z., Aggarwal, Rahul, Abida, Wassim, Feng, Felix Y., Small, Eric J., Spratt, Daniel E., Bankhead, Armand, Rao, Arvind, Gesner, Emily M., Attwell, Sarah, Lakhotia, Sanjay, Campeau, Eric, Yates, Joel A., Xia, Zheng, Alumkal, Joshi J.
Publicado 2021