SOX2 protein biochemistry in stemness, reprogramming, and cancer: the PI3K/AKT/SOX2 axis and beyond

por Schaefer, Thorsten, Lengerke, Claudia
Publicado 2019

Novel therapeutic options in Acute Myeloid Leukemia

por Medinger, Michael, Lengerke, Claudia, Passweg, Jakob
Publicado 2016

SOX2 and p53 Expression Control Converges in PI3K/AKT Signaling with Versatile Implications for Stemness and Cancer

por Schaefer, Thorsten, Steiner, Rebekah, Lengerke, Claudia
Publicado 2020

Pathogenesis of Acquired Aplastic Anemia and the Role of the Bone Marrow Microenvironment

por Medinger, Michael, Drexler, Beatrice, Lengerke, Claudia, Passweg, Jakob
Publicado 2018

The Laminin Receptors Basal Cell Adhesion Molecule/Lutheran and Integrin α7β1 on Human Hematopoietic Stem Cells

por Godavarthy, Parimala Sonika, Walter, Christina B., Lengerke, Claudia, Klein, Gerd
Publicado 2021

Stress and catecholamines modulate the bone marrow microenvironment to promote tumorigenesis

por Hanns, Pauline, Paczulla, Anna M., Medinger, Michael, Konantz, Martina, Lengerke, Claudia
Publicado 2019

Modeling hematopoietic disorders in zebrafish

por Konantz, Martina, Schürch, Christoph, Hanns, Pauline, Müller, Joëlle S., Sauteur, Loïc, Lengerke, Claudia
Publicado 2019

P462: RECIPIENT SEX AND DONOR RISK GROUP INFLUENCE LEUKEMIA KINETICS IN NSG MICE

por Arnone, Marlon, Stanger, Anna, Hanns, Pauline, Kuebler, Jessica, Goersch, Elsa, Rudat, Saskia, Lengerke, Claudia
Publicado 2023

P750: A ZEBRAFISH MODEL FOR JAGN1-ASSOCIATED SEVERE CONGENITAL NEUTROPENIA

por Doll, Larissa, Aghaallaei, Narges, Lengerke, Claudia, Zeidler, Cornelia, Welte, Karl, Skokowa, Julia, Bajoghli, Baubak
Publicado 2023

P1268: ALLOGENEIC HEMATOPOIETIC CELL TRANSPLANTATION FOR HIGH-RISK MYELODYSPLASTIC NEOPLASMS: A RETROSPECTIVE, SINGLE-CENTER ANALYSIS

por Christian Schröder, Jan, Faustmann, Philipp, Frederic Weller, Jan, Faul, Christoph, Lengerke, Claudia, Bethge, Wolfgang A.
Publicado 2023

PB1849: EARLY SALVAGE THERAPY WITH VENETOCLAX AND 10-DAY DECITABINE IS FEASIBLE AND SAFE IN REFRACTORY AML: RESULTS FROM 11 PATIENTS WITH EARLY INDUCTION FAILURE

por Borst, Carla, Ginsberg, Franziska, Weller, Jan, Vogel, Wichard, Faul, Christoph, Bethge, Wolfgang, Christopeit, Maximilian, Lengerke, Claudia
Publicado 2023

Acute Myeloid Leukemia Stem Cells: The Challenges of Phenotypic Heterogeneity

por Arnone, Marlon, Konantz, Martina, Hanns, Pauline, Paczulla Stanger, Anna M., Bertels, Sarah, Godavarthy, Parimala Sonika, Christopeit, Maximilian, Lengerke, Claudia
Publicado 2020

Value of CT-Textural Features and Volume-Based PET Parameters in Comparison to Serologic Markers for Response Prediction in Patients with Diffuse Large B-Cell Lymphoma Undergoing C...

por Reinert, Christian Philipp, Perl, Regine Mariette, Faul, Christoph, Lengerke, Claudia, Nikolaou, Konstantin, Dittmann, Helmut, Bethge, Wolfgang A., Horger, Marius
Publicado 2022

Uncovering NOTCH1 as a Promising Target in the Treatment of MLL-Rearranged Leukemia

por Fischer, Jacqueline, Erkner, Estelle, Fitzel, Rahel, Radszuweit, Pia, Keppeler, Hildegard, Korkmaz, Fulya, Roti, Giovanni, Lengerke, Claudia, Schneidawind, Dominik, Schneidawind, Corina
Publicado 2023

Patient Reported and Clinical Outcomes after High-Dose Chemotherapy and Autologous Stem Cell Transplantation in Primary Central Nervous System Lymphoma

por Beer, Sina A., Wirths, Stefan, Vogel, Wichard, Tabatabai, Ghazaleh, Ernemann, Ulrike, Merle, David A., Bethge, Wolfgang, Möhle, Robert, Lengerke, Claudia
Publicado 2023

Case Report: Paraneoplastic psoriasis in thymic carcinoma

por Mix, Lucas, Knoll, Manuel, Häring, Max-Felix, Bethge, Wolfgang Andreas, Schröder, Jan C., Forchhammer, Stephan, Krumm, Patrick, Schürch, Christian M., Schaller, Martin, Lengerke, Claudia
Publicado 2023

Long-term observation reveals high-frequency engraftment of human acute myeloid leukemia in immunodeficient mice

por Paczulla, Anna M., Dirnhofer, Stephan, Konantz, Martina, Medinger, Michael, Salih, Helmut R., Rothfelder, Kathrin, Tsakiris, Dimitrios A., Passweg, Jakob R., Lundberg, Pontus, Lengerke, Claudia
Publicado 2017

Targeting MYC in combination with epigenetic regulators induces synergistic anti-leukemic effects in MLLr leukemia and simultaneously improves immunity

por Fitzel, Rahel, Secker-Grob, Kathy-Ann, Keppeler, Hildegard, Korkmaz, Fulya, Schairer, Rebekka, Erkner, Estelle, Schneidawind, Dominik, Lengerke, Claudia, Hentrich, Thomas, Schulze-Hentrich, Julia M., Schneidawind, Corina
Publicado 2023

S178: A NEW HEREDITARY SYNDROME WITH SEVERE NEUTROPENIA AND NEUROLOGICAL INVOLVEMENT CAUSED BY THE AUTOSOMAL RECESSIVE COPZ1 MUTATION

por Borbaran Bravo, Natalia, Doll, Larissa, Deordieva, Ekaterina, Bräuning, Sandro, Dannenmann, Benjamin, Elgamacy, Mohammad, Zakharova, Viktoria, Lengerke, Claudia, Zeidler, Cornelia, Welte, Karl, Shcherbina, Anna, Skokowa, Julia, Klimiankou, Maksim
Publicado 2023

P1357: MILESTONE (MODIFYING ELANE GOLDBERG–HOGNES BOX TO INHIBIT EXPRESSION), A UNIVERSAL, SAFE AND EFFECTIVE CRISPR/CAS9N-MEDIATED GENOME EDITING STRATEGY FOR ELANE RELATED SEVERE...

por Nasri, Masoud, Ulrich Ritter, Malte, Mir, Perihan, Dannenmann, Benjamin, Monika Kaufmann, Masako, Xu, Yun, Borbaran-Bravo, Natalia, Klimiankou, Maksim, Lengerke, Claudia, Zeidler, Cornelia, Cathomen, Toni, Welte, Karl, Skokowa, Julia
Publicado 2023