Divergent Allele Advantage at Human MHC Genes: Signatures of Past and Ongoing Selection

por Pierini, Federica, Lenz, Tobias L
Publicado 2018

Unique Pathogen Peptidomes Facilitate Pathogen-Specific Selection and Specialization of MHC Alleles

por Özer, Onur, Lenz, Tobias L
Publicado 2021

Diverse MHC IIB allele repertoire increases parasite resistance and body condition in the Long-tailed giant rat (Leopoldamys sabanus)

por Lenz, Tobias L, Wells, Konstans, Pfeiffer, Martin, Sommer, Simone
Publicado 2009

Rapid and adaptive evolution of MHC genes under parasite selection in experimental vertebrate populations

por Eizaguirre, Christophe, Lenz, Tobias L., Kalbe, Martin, Milinski, Manfred
Publicado 2012

Divergent selection on locally adapted major histocompatibility complex immune genes experimentally proven in the field

por Eizaguirre, Christophe, Lenz, Tobias L, Kalbe, Martin, Milinski, Manfred
Publicado 2012

Experimental parasite infection reveals costs and benefits of paternal effects

por Kaufmann, Joshka, Lenz, Tobias L, Milinski, Manfred, Eizaguirre, Christophe
Publicado 2014

RSCA genotyping of MHC for high-throughput evolutionary studies in the model organism three-spined stickleback Gasterosteus aculeatus

por Lenz, Tobias L, Eizaguirre, Christophe, Becker, Sven, Reusch, Thorsten BH
Publicado 2009

Exploring local immunological adaptation of two stickleback ecotypes by experimental infection and transcriptome-wide digital gene expression analysis

por Lenz, Tobias L, Eizaguirre, Christophe, Rotter, Björn, Kalbe, Martin, Milinski, Manfred
Publicado 2013

Excess of Deleterious Mutations around HLA Genes Reveals Evolutionary Cost of Balancing Selection

por Lenz, Tobias L., Spirin, Victor, Jordan, Daniel M., Sunyaev, Shamil R.
Publicado 2016

Challenges and opportunities in analyzing and modeling peptide presentation by HLA-II proteins

por ElAbd, Hesham, Bacher, Petra, Tholey, Andreas, Lenz, Tobias L., Franke, Andre
Publicado 2023

Individual HLA heterogeneity and its implications for cellular immune evasion in cancer and beyond

por Pagliuca, Simona, Gurnari, Carmelo, Rubio, Marie Thérèse, Visconte, Valeria, Lenz, Tobias L.
Publicado 2022

Cryptic haplotype‐specific gamete selection yields offspring with optimal MHC immune genes

por Lenz, Tobias L., Hafer, Nina, Samonte, Irene E., Yeates, Sarah E., Milinski, Manfred
Publicado 2018

Experimental Parasite Infection Causes Genome-Wide Changes in DNA Methylation

por Sagonas, Kostas, Meyer, Britta S, Kaufmann, Joshka, Lenz, Tobias L, Häsler, Robert, Eizaguirre, Christophe
Publicado 2020

Induction of diploid gynogenesis in an evolutionary model organism, the three-spined stickleback (Gasterosteus aculeatus)

por Samonte-Padilla, Irene E, Eizaguirre, Christophe, Scharsack, Jörn P, Lenz, Tobias L, Milinski, Manfred
Publicado 2011

Pathogen diversity drives the evolution of generalist MHC-II alleles in human populations

por Manczinger, Máté, Boross, Gábor, Kemény, Lajos, Müller, Viktor, Lenz, Tobias L., Papp, Balázs, Pál, Csaba
Publicado 2019

HLA Heterozygote Advantage against HIV-1 Is Driven by Quantitative and Qualitative Differences in HLA Allele-Specific Peptide Presentation

por Arora, Jatin, Pierini, Federica, McLaren, Paul J, Carrington, Mary, Fellay, Jacques, Lenz, Tobias L
Publicado 2020

Ancient DNA Study in Medieval Europeans Shows an Association Between HLA-DRB1*03 and Paratyphoid Fever

por Haller, Magdalena, Bonczarowska, Joanna H., Rieger, Dirk, Lenz, Tobias L., Nebel, Almut, Krause-Kyora, Ben
Publicado 2021

Common Denominators in the Immunobiology of IgG4 Autoimmune Diseases: What Do Glomerulonephritis, Pemphigus Vulgaris, Myasthenia Gravis, Thrombotic Thrombocytopenic Purpura and Aut...

por Koneczny, Inga, Yilmaz, Vuslat, Lazaridis, Konstantinos, Tzartos, John, Lenz, Tobias L., Tzartos, Socrates, Tüzün, Erdem, Leypoldt, Frank
Publicado 2021

Immunopeptidomics toolkit library (IPTK): a python-based modular toolbox for analyzing immunopeptidomics data

por ElAbd, Hesham, Degenhardt, Frauke, Koudelka, Tomas, Kamps, Ann-Kristin, Tholey, Andreas, Bacher, Petra, Lenz, Tobias L., Franke, Andre, Wendorff, Mareike
Publicado 2021

Intronic primers reveal unexpectedly high major histocompatibility complex diversity in Antarctic fur seals

por Tebbe, Jonas, Ottensmann, Meinolf, Havenstein, Katja, Efstratiou, Artemis, Lenz, Tobias L., Caspers, Barbara A., Forcada, Jaume, Tiedemann, Ralph, Hoffman, Joseph I.
Publicado 2022