Investigating the state of physiologically based kinetic modelling practices and challenges associated with gaining regulatory acceptance of model applications

por Paini, Alicia, Leonard, Jeremy A., Kliment, Tomas, Tan, Yu-Mei, Worth, Andrew
Publicado 2017

A Workflow to Investigate Exposure and Pharmacokinetic Influences on High-Throughput in Vitro Chemical Screening Based on Adverse Outcome Pathways

por Phillips, Martin B., Leonard, Jeremy A., Grulke, Christopher M., Chang, Daniel T., Edwards, Stephen W., Brooks, Raina, Goldsmith, Michael-Rock, El-Masri, Hisham, Tan, Yu-Mei
Publicado 2015

Considerations for Improving Metabolism Predictions for In Vitro to In Vivo Extrapolation

por Moreau, Marjory, Mallick, Pankajini, Smeltz, Marci, Haider, Saad, Nicolas, Chantel I., Pendse, Salil N., Leonard, Jeremy A., Linakis, Matthew W., McMullen, Patrick D., Clewell, Rebecca A., Clewell, Harvey J., Yoon, Miyoung
Publicado 2022

Developing a Physiologically-Based Pharmacokinetic Model Knowledgebase in Support of Provisional Model Construction

por Lu, Jingtao, Goldsmith, Michael-Rock, Grulke, Christopher M., Chang, Daniel T., Brooks, Raina D., Leonard, Jeremy A., Phillips, Martin B., Hypes, Ethan D., Fair, Matthew J., Tornero-Velez, Rogelio, Johnson, Jeffre, Dary, Curtis C., Tan, Yu-Mei
Publicado 2016