A critical evaluation of protein kinase regulation by activation loop autophosphorylation

por Reinhardt, Ronja, Leonard, Thomas A
Publicado 2023

Coiled‐coils: The long and short of it

por Truebestein, Linda, Leonard, Thomas A.
Publicado 2016

Lipid-dependent Akt-ivity: where, when, and how

por Siess, Katharina M., Leonard, Thomas A.
Publicado 2019

Made to measure – keeping Rho kinase at a distance

por Truebestein, Linda, Elsner, Daniel J., Leonard, Thomas A.
Publicado 2016

A switch in nucleotide affinity governs activation of the Src and Tec family kinases

por von Raußendorf, Freia, de Ruiter, Anita, Leonard, Thomas A.
Publicado 2017

A molecular ruler regulates cytoskeletal remodelling by the Rho kinases

por Truebestein, Linda, Elsner, Daniel J., Fuchs, Elisabeth, Leonard, Thomas A.
Publicado 2015

Activation of the essential kinase PDK1 by phosphoinositide-driven trans-autophosphorylation

por Levina, Aleksandra, Fleming, Kaelin D., Burke, John E., Leonard, Thomas A.
Publicado 2022

A ubiquitin-like domain controls protein kinase D dimerization and activation by trans-autophosphorylation

por Elsner, Daniel J., Siess, Katharina M., Gossenreiter, Thomas, Hartl, Markus, Leonard, Thomas A.
Publicado 2019

In vitro reconstitution of Sgk3 activation by phosphatidylinositol 3-phosphate

por Pokorny, Daniel, Truebestein, Linda, Fleming, Kaelin D., Burke, John E., Leonard, Thomas A.
Publicado 2021

Conformational sampling of membranes by Akt controls its activation and inactivation

por Lučić, Iva, Rathinaswamy, Manoj K., Truebestein, Linda, Hamelin, David J., Burke, John E., Leonard, Thomas A.
Publicado 2018

PKD autoinhibition in trans regulates activation loop autophosphorylation in cis

por Reinhardt, Ronja, Hirzel, Kai, Link, Gisela, Eisler, Stephan A., Hägele, Tanja, Parson, Matthew A. H., Burke, John E., Hausser, Angelika, Leonard, Thomas A.
Publicado 2023

COORDINATED ACTIVATION OF THE RAC-GAP β2-CHIMAERIN BY AN ATYPICAL PROLINE-RICH DOMAIN AND DIACYLGLYCEROL

por Gutierrez-Uzquiza, Alvaro, Colon-Gonzalez, Francheska, Leonard, Thomas A., Canagarajah, Bertram J., Wang, HongBin, Mayer, Bruce J., Hurley, James H., Kazanietz, Marcelo G.
Publicado 2013

Structure of autoinhibited Akt1 reveals mechanism of PIP(3)-mediated activation

por Truebestein, Linda, Hornegger, Harald, Anrather, Dorothea, Hartl, Markus, Fleming, Kaelin D., Stariha, Jordan T. B., Pardon, Els, Steyaert, Jan, Burke, John E., Leonard, Thomas A.
Publicado 2021

Molecular basis for the recruitment of the Rab effector protein WDR44 by the GTPase Rab11

por Thibodeau, Matthew C., Harris, Noah J., Jenkins, Meredith L., Parson, Matthew A.H., Evans, John T., Scott, Mackenzie K., Shaw, Alexandria L., Pokorný, Daniel, Leonard, Thomas A., Burke, John E.
Publicado 2022

Structures of three MORN repeat proteins and a re-evaluation of the proposed lipid-binding properties of MORN repeats

por Sajko, Sara, Grishkovskaya, Irina, Kostan, Julius, Graewert, Melissa, Setiawan, Kim, Trübestein, Linda, Niedermüller, Korbinian, Gehin, Charlotte, Sponga, Antonio, Puchinger, Martin, Gavin, Anne-Claude, Leonard, Thomas A., Svergun, Dimitri I., Smith, Terry K., Morriswood, Brooke, Djinovic-Carugo, Kristina
Publicado 2020