Rare, high-affinity mouse anti-PD-1 antibodies that function in checkpoint blockade, discovered using microfluidics and molecular genomics

por Adler, Adam S., Mizrahi, Rena A., Spindler, Matthew J., Adams, Matthew S., Asensio, Michael A., Edgar, Robert C., Leong, Jackson, Leong, Renee, Johnson, David S.
Publicado 2017

Rare, high-affinity anti-pathogen antibodies from human repertoires, discovered using microfluidics and molecular genomics

por Adler, Adam S., Mizrahi, Rena A., Spindler, Matthew J., Adams, Matthew S., Asensio, Michael A., Edgar, Robert C., Leong, Jackson, Leong, Renee, Roalfe, Lucy, White, Rebecca, Goldblatt, David, Johnson, David S.
Publicado 2017

Antibody repertoire analysis of mouse immunization protocols using microfluidics and molecular genomics

por Asensio, Michael A., Lim, Yoong Wearn, Wayham, Nicholas, Stadtmiller, Kacy, Edgar, Robert C., Leong, Jackson, Leong, Renee, Mizrahi, Rena A., Adams, Matthew S., Simons, Jan Fredrik, Spindler, Matthew J., Johnson, David S., Adler, Adam S.
Publicado 2019

A natively paired antibody library yields drug leads with higher sensitivity and specificity than a randomly paired antibody library

por Adler, Adam S., Bedinger, Daniel, Adams, Matthew S., Asensio, Michael A., Edgar, Robert C., Leong, Renee, Leong, Jackson, Mizrahi, Rena A., Spindler, Matthew J., Bandi, Srinivasa Rao, Huang, Haichun, Tawde, Pallavi, Brams, Peter, Johnson, David S.
Publicado 2018

Preferential Identification of Agonistic OX40 Antibodies by Using Cell Lysate to Pan Natively Paired, Humanized Mouse-Derived Yeast Surface Display Libraries

por Medina-Cucurella, Angélica V., Mizrahi, Rena A., Asensio, Michael A., Edgar, Robert C., Leong, Jackson, Leong, Renee, Lim, Yoong Wearn, Nelson, Ayla, Niedecken, Ariel R., Simons, Jan Fredrik, Spindler, Matthew J., Stadtmiller, Kacy, Wayham, Nicholas, Adler, Adam S., Johnson, David S.
Publicado 2019

GMP Manufacturing and IND-Enabling Studies of a Recombinant Hyperimmune Globulin Targeting SARS-CoV-2

por Mizrahi, Rena A., Lin, Wendy Y., Gras, Ashley, Niedecken, Ariel R., Wagner, Ellen K., Keating, Sheila M., Ikon, Nikita, Manickam, Vishal A., Asensio, Michael A., Leong, Jackson, Medina-Cucurella, Angelica V., Benzie, Emily, Carter, Kyle P., Chiang, Yao, Edgar, Robert C., Leong, Renee, Lim, Yoong Wearn, Simons, Jan Fredrik, Spindler, Matthew J., Stadtmiller, Kacy, Wayham, Nicholas, Büscher, Dirk, Terencio, Jose Vicente, Germanio, Clara Di, Chamow, Steven M., Olson, Charles, Pino, Paula A., Park, Jun-Gyu, Hicks, Amberlee, Ye, Chengjin, Garcia-Vilanova, Andreu, Martinez-Sobrido, Luis, Torrelles, Jordi B., Johnson, David S., Adler, Adam S.
Publicado 2022

Generation of recombinant hyperimmune globulins from diverse B-cell repertoires

por Keating, Sheila M., Mizrahi, Rena A., Adams, Matthew S., Asensio, Michael A., Benzie, Emily, Carter, Kyle P., Chiang, Yao, Edgar, Robert C., Gautam, Bishal K., Gras, Ashley, Leong, Jackson, Leong, Renee, Wearn Lim, Yoong, Manickam, Vishal A., Medina-Cucurella, Angelica V., Niedecken, Ariel R., Saini, Jasmeen, Fredrik Simons, Jan, Spindler, Matthew J., Stadtmiller, Kacy, Tinsley, Brendan, Wagner, Ellen K., Wayham, Nicholas, Tracy, LaRee, Vingsbo Lundberg, Carina, Büscher, Dirk, Vicente Terencio, Jose, Roalfe, Lucy, Pearce, Emma, Richardson, Hayley, Goldblatt, David, Ramjag, Anushka T., Carrington, Christine V.F., Simmons, Graham, Muench, Marcus O., Chamow, Steven M., Monroe, Bryan, Olson, Charles, Oguin, Thomas H., Lynch, Heather, Jeanfreau, Robert, Mosher, Rachel A., Walch, Matthew J., Bartley, Christopher R., Ross, Carl A., Meyer, Everett H., Adler, Adam S., Johnson, David S.
Publicado 2021