DNA damaging agents and p53 do not cause senescence in quiescent cells, while consecutive re-activation of mTOR is associated with conversion to senescence

por Leontieva, Olga V., Blagosklonny, Mikhail V.
Publicado 2010

Yeast-like chronological senescence in mammalian cells: phenomenon, mechanism and pharmacological suppression

por Leontieva, Olga V., Blagosklonny, Mikhail V.
Publicado 2011

CDK4/6-inhibiting drug substitutes for p21 and p16 in senescence: Duration of cell cycle arrest and MTOR activity determine geroconversion

por Leontieva, Olga V, Blagosklonny, Mikhail V
Publicado 2013

Gerosuppression in confluent cells

por Leontieva, Olga V., Blagosklonny, Mikhail V.
Publicado 2014

Tumor promoter-induced cellular senescence: cell cycle arrest followed by geroconversion

por Leontieva, Olga V., Blagosklonny, Mikhail V.
Publicado 2014

Gerosuppression by pan-mTOR inhibitors

por Leontieva, Olga V., Blagosklonny, Mikhail V.
Publicado 2016

While reinforcing cell cycle arrest, rapamycin and Torins suppress senescence in UVA-irradiated fibroblasts

por Leontieva, Olga V., Blagosklonny, Mikhail V.
Publicado 2017

Mechanistic or mammalian target of rapamycin (mTOR) may determine robustness in young male mice at the cost of accelerated aging

por Leontieva, Olga V., Paszkiewicz, Geraldine M., Blagosklonny, Mikhail V.
Publicado 2012

S6K in geroconversion

por Leontieva, Olga V, Demidenko, Zoya N, Blagosklonny, Mikhail V
Publicado 2013

Weekly administration of rapamycin improves survival and biomarkers in obese male mice on high-fat diet

por Leontieva, Olga V, Paszkiewicz, Geraldine M, Blagosklonny, Mikhail V
Publicado 2014

Dual mTORC1/C2 inhibitors suppress cellular geroconversion (a senescence program)

por Leontieva, Olga V., Demidenko, Zoya N., Blagosklonny, Mikhail V.
Publicado 2015

Hyper-mitogenic drive coexists with mitotic incompetence in senescent cells

por Leontieva, Olga V., Lenzo, Felicia, Demidenko, Zoya N., Blagosklonny, Mikhail V.
Publicado 2012

Elimination of Proliferating Cells Unmasks the Shift from Senescence to Quiescence Caused by Rapamycin

por Leontieva, Olga V., Demidenko, Zoya N., Gudkov, Andrei V., Blagosklonny, Mikhail V.
Publicado 2011

Exploring long-term protection of normal human fibroblasts and epithelial cells from chemotherapy in cell culture

por Apontes, Pasha, Leontieva, Olga V., Demidenko, Zoya N., Li, Fengzhi, Blagosklonny, Mikhail V.
Publicado 2011

Protein Kinase C Signaling Mediates a Program of Cell Cycle Withdrawal in the Intestinal Epithelium

por Frey, Mark R., Clark, Jennifer A., Leontieva, Olga, Uronis, Joshua M., Black, Adrian R., Black, Jennifer D.
Publicado 2000

The choice between p53-induced senescence and quiescence is determined in part by the mTOR pathway

por Korotchkina, Lioubov G., Leontieva, Olga V., Bukreeva, Elena I., Demidenko, Zoya N., Gudkov, Andrei V., Blagosklonny, Mikhail V.
Publicado 2010

Recent progress in genetics of aging, senescence and longevity: focusing on cancer-related genes

por Berman, Albert E., Leontieva, Olga V., Natarajan, Venkatesh, McCubrey, James A., Demidenko, Zoya N., Nikiforov, Mikhail A.
Publicado 2012

Rapamycin extends lifespan and delays tumorigenesis in heterozygous p53+/− mice

por Komarova, Elena A., Antoch, Marina P., Novototskaya, Liliya R., Chernova, Olga B., Paszkiewicz, Geraldine, Leontieva, Olga V., Blagosklonny, Mikhail V., Gudkov, Andrei V.
Publicado 2012

Immune checkpoint protein VSIG4 as a biomarker of aging in murine adipose tissue

por Hall, Brandon M., Gleiberman, Anatoli S., Strom, Evguenia, Krasnov, Peter A., Frescas, David, Vujcic, Slavoljub, Leontieva, Olga V., Antoch, Marina P., Kogan, Valeria, Koman, Igor E., Zhu, Yi, Tchkonia, Tamara, Kirkland, James L., Chernova, Olga B., Gudkov, Andrei V.
Publicado 2020

Cancer Relevance of Circulating Antibodies Against LINE-1 Antigens in Humans

por Vylegzhanina, Alexandra V., Bespalov, Ivan A., Novototskaya-Vlasova, Ksenia A., Hall, Brandon M., Gleiberman, Anatoli S., Yu, Han, Leontieva, Olga V., Leonova, Katerina I., Kurnasov, Oleg V., Osterman, Andrei L., Dy, Grace K., Komissarov, Alexey A., Vasilieva, Elena, Gehlhausen, Jeff, Iwasaki, Akiko, Ambrosone, Christine B., Tsuji, Takemasa, Matsuzaki, Junko, Odunsi, Kunle, Andrianova, Ekaterina L., Gudkov, Andrei V.
Publicado 2023