mGluR2/3 blockade produces rapid and long-lasting reversal of anhedonia caused by chronic stress exposure

por Dwyer, Jason M, Lepack, Ashley E, Duman, Ronald S
Publicado 2013

BDNF Release Is Required for the Behavioral Actions of Ketamine

por Lepack, Ashley E., Fuchikami, Manabu, Dwyer, Jason M., Banasr, Mounira, Duman, Ronald S.
Publicado 2014

Histone H3 dopaminylation in ventral tegmental area underlies heroin-induced transcriptional and behavioral plasticity in male rats

por Fulton, Sasha L., Mitra, Swarup, Lepack, Ashley E., Martin, Jennifer A., Stewart, Andrew F., Converse, Jacob, Hochstetler, Mason, Dietz, David M., Maze, Ian
Publicado 2022

Histone H3 serotonylation dynamics in dorsal raphe nucleus contribute to stress- and antidepressant-mediated gene expression and behavior

por Al-Kachak, Amni, Fulton, Sasha L., Di Salvo, Giuseppina, Chan, Jennifer C, Farrelly, Lorna A., Lepack, Ashley E., Bastle, Ryan M., Kong, Lingchun, Cathomas, Flurin, Newman, Emily L., Menard, Caroline, Ramakrishnan, Aarthi, Safovich, Polina, Lyu, Yang, Covington, Herbert E., Shen, Li, Gleason, Kelly, Tamminga, Carol A., Russo, Scott J., Maze, Ian
Publicado 2023

ZBTB7A regulates MDD-specific chromatin signatures and astrocyte-mediated stress vulnerability in orbitofrontal cortex

por Fulton, Sasha L., Bendl, Jaroslav, Gameiro-Ros, Isabel, Fullard, John F., Al-Kachak, Amni, Lepack, Ashley E., Stewart, Andrew F., Singh, Sumnima, Poller, Wolfram C., Bastle, Ryan M., Hauberg, Mads E., Fakira, Amanda K., Chen, Min, Cuttoli, Romain Durand-de, Cathomas, Flurin, Ramakrishnan, Aarthi, Gleason, Kelly, Shen, Li, Tamminga, Carol A., Milosevic, Ana, Russo, Scott J., Swirski, Filip, Blitzer, Robert D., Slesinger, Paul A., Roussos, Panos, Maze, Ian
Publicado 2023

Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3

por Farrelly, Lorna A., Thompson, Robert E., Zhao, Shuai, Lepack, Ashley E., Lyu, Yang, Bhanu, Natarajan V., Zhang, Baichao, Loh, Yong-Hwee E., Ramakrishnan, Aarthi, Vadodaria, Krishna C., Heard, Kelly J., Erikson, Galina, Nakadai, Tomoyoshi, Bastle, Ryan M., Lukasak, Bradley J., Zebroski, Henry, Alenina, Natalia, Bader, Michael, Berton, Olivier, Roeder, Robert G., Molina, Henrik, Gage, Fred H., Shen, Li, Garcia, Benjamin A., Li, Haitao, Muir, Tom W., Maze, Ian
Publicado 2019

Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex

por Lorsch, Zachary S., Hamilton, Peter J., Ramakrishnan, Aarthi, Parise, Eric M., Salery, Marine, Wright, William J., Lepack, Ashley E., Mews, Philipp, Issler, Orna, McKenzie, Andrew, Zhou, Xianxiao, Parise, Lyonna F., Pirpinias, Stephen T., Torres, Idelisse Ortiz, Kronman, Hope G., Montgomery, Sarah E., Loh, Yong-Hwee Eddie, Labonté, Benoit, Conkey, Andrew, Symonds, Ann E., Neve, Rachael L., Turecki, Gustavo, Maze, Ian, Dong, Yan, Zhang, Bin, Shen, Li, Bagot, Rosemary C., Nestler, Eric J.
Publicado 2019

Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome

por Fulton, Sasha L., Wenderski, Wendy, Lepack, Ashley E., Eagle, Andrew L., Fanutza, Tomas, Bastle, Ryan M., Ramakrishnan, Aarthi, Hays, Emma C., Neal, Arianna, Bendl, Jaroslav, Farrelly, Lorna A., Al-Kachak, Amni, Lyu, Yang, Cetin, Bulent, Chan, Jennifer C., Tran, Tina N., Neve, Rachael L., Roper, Randall J., Brennand, Kristen J., Roussos, Panos, Schimenti, John C., Friedman, Allyson K., Shen, Li, Blitzer, Robert D., Robison, Alfred J., Crabtree, Gerald R., Maze, Ian
Publicado 2022