IFT trains overcome an NPHP module barrier at the transition zone

por Park, Kwangjin, Leroux, Michel R.
Publicado 2021

Mutations in a Guanylate Cyclase GCY-35/GCY-36 Modify Bardet-Biedl Syndrome–Associated Phenotypes in Caenorhabditis elegans

por Mok, Calvin A., Healey, Michael P., Shekhar, Tanvi, Leroux, Michel R., Héon, Elise, Zhen, Mei
Publicado 2011

CDKL Family Kinases Have Evolved Distinct Structural Features and Ciliary Function

por Canning, Peter, Park, Kwangjin, Gonçalves, João, Li, Chunmei, Howard, Conor J., Sharpe, Timothy D., Holt, Liam J., Pelletier, Laurence, Bullock, Alex N., Leroux, Michel R.
Publicado 2018

Mechanism of transport of IFT particles in C. elegans cilia by the concerted action of kinesin-II and OSM-3 motors

por Pan, Xiaoyu, Ou, Guangshuo, Civelekoglu-Scholey, Gul, Blacque, Oliver E., Endres, Nicholas F., Tao, Li, Mogilner, Alex, Leroux, Michel R., Vale, Ronald D., Scholey, Jonathan M.
Publicado 2006

Conserved Genetic Interactions between Ciliopathy Complexes Cooperatively Support Ciliogenesis and Ciliary Signaling

por Yee, Laura E., Garcia-Gonzalo, Francesc R., Bowie, Rachel V., Li, Chunmei, Kennedy, Julie K., Ashrafi, Kaveh, Blacque, Oliver E., Leroux, Michel R., Reiter, Jeremy F.
Publicado 2015

Bardet-Biedl Syndrome-associated Small GTPase ARL6 (BBS3) Functions at or near the Ciliary Gate and Modulates Wnt Signaling

por Wiens, Cheryl J., Tong, Yufeng, Esmail, Muneer A., Oh, Edwin, Gerdes, Jantje M., Wang, Jihong, Tempel, Wolfram, Rattner, Jerome B., Katsanis, Nicholas, Park, Hee-Won, Leroux, Michel R.
Publicado 2010

Localization of a Guanylyl Cyclase to Chemosensory Cilia Requires the Novel Ciliary MYND Domain Protein DAF-25

por Jensen, Victor L., Bialas, Nathan J., Bishop-Hurley, Sharon L., Molday, Laurie L., Kida, Katarzyna, Nguyen, Phuong Anh T., Blacque, Oliver E., Molday, Robert S., Leroux, Michel R., Riddle, Donald L.
Publicado 2010

MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis

por Williams, Corey L., Li, Chunmei, Kida, Katarzyna, Inglis, Peter N., Mohan, Swetha, Semenec, Lucie, Bialas, Nathan J., Stupay, Rachel M., Chen, Nansheng, Blacque, Oliver E., Yoder, Bradley K., Leroux, Michel R.
Publicado 2011

PACRG, a protein linked to ciliary motility, mediates cellular signaling

por Loucks, Catrina M., Bialas, Nathan J., Dekkers, Martijn P. J., Walker, Denise S., Grundy, Laura J., Li, Chunmei, Inglis, P. Nick, Kida, Katarzyna, Schafer, William R., Blacque, Oliver E., Jansen, Gert, Leroux, Michel R.
Publicado 2016

Whole-Organism Developmental Expression Profiling Identifies RAB-28 as a Novel Ciliary GTPase Associated with the BBSome and Intraflagellar Transport

por Jensen, Victor L., Carter, Stephen, Sanders, Anna A. W. M., Li, Chunmei, Kennedy, Julie, Timbers, Tiffany A., Cai, Jerry, Scheidel, Noemie, Kennedy, Breandán N., Morin, Ryan D., Leroux, Michel R., Blacque, Oliver E.
Publicado 2016

Identification of 526 Conserved Metazoan Genetic Innovations Exposes a New Role for Cofactor E-like in Neuronal Microtubule Homeostasis

por Frédéric, Melissa Y., Lundin, Victor F., Whiteside, Matthew D., Cueva, Juan G., Tu, Domena K., Kang, S. Y. Catherine, Singh, Hansmeet, Baillie, David L., Hutter, Harald, Goodman, Miriam B., Brinkman, Fiona S. L., Leroux, Michel R.
Publicado 2013

Accelerating Gene Discovery by Phenotyping Whole-Genome Sequenced Multi-mutation Strains and Using the Sequence Kernel Association Test (SKAT)

por Timbers, Tiffany A., Garland, Stephanie J., Mohan, Swetha, Flibotte, Stephane, Edgley, Mark, Muncaster, Quintin, Au, Vinci, Li-Leger, Erica, Rosell, Federico I., Cai, Jerry, Rademakers, Suzanne, Jansen, Gert, Moerman, Donald G., Leroux, Michel R.
Publicado 2016

An Essential Role for DYF-11/MIP-T3 in Assembling Functional Intraflagellar Transport Complexes

por Li, Chunmei, Inglis, Peter N., Leitch, Carmen C., Efimenko, Evgeni, Zaghloul, Norann A., Mok, Calvin A., Davis, Erica E., Bialas, Nathan J., Healey, Michael P., Héon, Elise, Zhen, Mei, Swoboda, Peter, Katsanis, Nicholas, Leroux, Michel R.
Publicado 2008

EFHC1, implicated in juvenile myoclonic epilepsy, functions at the cilium and synapse to modulate dopamine signaling

por Loucks, Catrina M, Park, Kwangjin, Walker, Denise S, McEwan, Andrea H, Timbers, Tiffany A, Ardiel, Evan L, Grundy, Laura J, Li, Chunmei, Johnson, Jacque-Lynne, Kennedy, Julie, Blacque, Oliver E, Schafer, William, Rankin, Catharine H, Leroux, Michel R
Publicado 2019

Identification of ciliary and ciliopathy genes in Caenorhabditis elegans through comparative genomics

por Chen, Nansheng, Mah, Allan, Blacque, Oliver E, Chu, Jeffrey, Phgora, Kiran, Bakhoum, Mathieu W, Hunt Newbury, C Rebecca, Khattra, Jaswinder, Chan, Susanna, Go, Anne, Efimenko, Evgeni, Johnsen, Robert, Phirke, Prasad, Swoboda, Peter, Marra, Marco, Moerman, Donald G, Leroux, Michel R, Baillie, David L, Stein, Lincoln D
Publicado 2006

MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition Zone

por Li, Chunmei, Jensen, Victor L., Park, Kwangjin, Kennedy, Julie, Garcia-Gonzalo, Francesc R., Romani, Marta, De Mori, Roberta, Bruel, Ange-Line, Gaillard, Dominique, Doray, Bérénice, Lopez, Estelle, Rivière, Jean-Baptiste, Faivre, Laurence, Thauvin-Robinet, Christel, Reiter, Jeremy F., Blacque, Oliver E., Valente, Enza Maria, Leroux, Michel R.
Publicado 2016

TMEM231, mutated in orofaciodigital and Meckel syndromes, organizes the ciliary transition zone

por Roberson, Elle C., Dowdle, William E., Ozanturk, Aysegul, Garcia-Gonzalo, Francesc R., Li, Chunmei, Halbritter, Jan, Elkhartoufi, Nadia, Porath, Jonathan D., Cope, Heidi, Ashley-Koch, Allison, Gregory, Simon, Thomas, Sophie, Sayer, John A., Saunier, Sophie, Otto, Edgar A., Katsanis, Nicholas, Davis, Erica E., Attié-Bitach, Tania, Hildebrandt, Friedhelm, Leroux, Michel R., Reiter, Jeremy F.
Publicado 2015

The inner junction protein CFAP20 functions in motile and non-motile cilia and is critical for vision

por Chrystal, Paul W., Lambacher, Nils J., Doucette, Lance P., Bellingham, James, Schiff, Elena R., Noel, Nicole C. L., Li, Chunmei, Tsiropoulou, Sofia, Casey, Geoffrey A., Zhai, Yi, Nadolski, Nathan J., Majumder, Mohammed H., Tagoe, Julia, D’Esposito, Fabiana, Cordeiro, Maria Francesca, Downes, Susan, Clayton-Smith, Jill, Ellingford, Jamie, Mahroo, Omar A., Hocking, Jennifer C., Cheetham, Michael E., Webster, Andrew R., Jansen, Gert, Blacque, Oliver E., Allison, W. Ted, Au, Ping Yee Billie, MacDonald, Ian M., Arno, Gavin, Leroux, Michel R.
Publicado 2022

CiliaCarta: An integrated and validated compendium of ciliary genes

por van Dam, Teunis J. P., Kennedy, Julie, van der Lee, Robin, de Vrieze, Erik, Wunderlich, Kirsten A., Rix, Suzanne, Dougherty, Gerard W., Lambacher, Nils J., Li, Chunmei, Jensen, Victor L., Leroux, Michel R., Hjeij, Rim, Horn, Nicola, Texier, Yves, Wissinger, Yasmin, van Reeuwijk, Jeroen, Wheway, Gabrielle, Knapp, Barbara, Scheel, Jan F., Franco, Brunella, Mans, Dorus A., van Wijk, Erwin, Képès, François, Slaats, Gisela G., Toedt, Grischa, Kremer, Hannie, Omran, Heymut, Szymanska, Katarzyna, Koutroumpas, Konstantinos, Ueffing, Marius, Nguyen, Thanh-Minh T., Letteboer, Stef J. F., Oud, Machteld M., van Beersum, Sylvia E. C., Schmidts, Miriam, Beales, Philip L., Lu, Qianhao, Giles, Rachel H., Szklarczyk, Radek, Russell, Robert B., Gibson, Toby J., Johnson, Colin A., Blacque, Oliver E., Wolfrum, Uwe, Boldt, Karsten, Roepman, Ronald, Hernandez-Hernandez, Victor, Huynen, Martijn A.
Publicado 2019