Bring on the brequinar: an approach to enforce the differentiation of myeloid-derived suppressor cells

por Horvat, Natalie K., Lesinski, Gregory B.
Publicado 2022

Pancreatic cancer-associated stellate cells: A viable target for reducing immunosuppression in the tumor microenvironment

por Mace, Thomas A, Bloomston, Mark, Lesinski, Gregory B
Publicado 2013

Mirage or long-awaited oasis: reinvigorating T-cell responses in pancreatic cancer

por Ware, Michael Brandon, El-Rayes, Bassel F, Lesinski, Gregory B
Publicado 2020

The Potential of CAR T Cell Therapy in Pancreatic Cancer

por Akce, Mehmet, Zaidi, Mohammad Y., Waller, Edmund K., El-Rayes, Bassel F., Lesinski, Gregory B.
Publicado 2018

Whole-exome tumor sequencing study in biliary cancer patients with a response to MEK inhibitors

por Ahn, Daniel H., Ozer, Hatice Gulcin, Hancioglu, Baris, Lesinski, Gregory B., Timmers, Cynthia, Bekaii-Saab, Tanios
Publicado 2015

Immune checkpoint inhibitors for the treatment of MSI-H/MMR-D colorectal cancer and a perspective on resistance mechanisms

por Sahin, Ibrahim Halil, Akce, Mehmet, Alese, Olatunji, Shaib, Walid, Lesinski, Gregory B., El-Rayes, Bassel, Wu, Christina
Publicado 2019

Short-Term Soy Bread Intervention Leads to a Dose-Response Increase in Urinary Isoflavone Metabolites and Satiety in Chronic Pancreatitis

por Ahn-Jarvis, Jennifer H., Sosh, Daniel, Lombardo, Erin, Lesinski, Gregory B., Conwell, Darwin L., Hart, Phil A., Vodovotz, Yael
Publicado 2023

Modulation of the tumor microenvironment by armed vesicular stomatitis virus in a syngeneic pancreatic cancer model

por Tang, Sijia, Shi, Lei, Luker, Breona T., Mickler, Channen, Suresh, Bhavana, Lesinski, Gregory B., Fan, Daping, Liu, Yuan, Luo, Ming
Publicado 2022

Modulation of SOCS protein expression influences the interferon responsiveness of human melanoma cells

por Lesinski, Gregory B, Zimmerer, Jason M, Kreiner, Melanie, Trefry, John, Bill, Matthew A, Young, Gregory S, Becknell, Brian, Carson, William E
Publicado 2010

Intestinal Microbial Dysbiosis and Colonic Epithelial Cell Hyperproliferation by Dietary α-Mangostin is Independent of Mouse Strain

por Gutierrez-Orozco, Fabiola, Thomas-Ahner, Jennifer M., Galley, Jeffrey D., Bailey, Michael T., Clinton, Steven K., Lesinski, Gregory B., Failla, Mark L.
Publicado 2015

MEK inhibition suppresses B regulatory cells and augments anti-tumor immunity

por Yarchoan, Mark, Mohan, Aditya A., Dennison, Lauren, Vithayathil, Teena, Ruggieri, Amanda, Lesinski, Gregory B., Armstrong, Todd D., Azad, Nilofer S., Jaffee, Elizabeth M.
Publicado 2019

Statin drugs enhance responses to immune checkpoint blockade in head and neck cancer models

por Kansal, Vikash, Burnham, Andre J, Kinney, Brendan L C, Saba, Nabil F, Paulos, Chrystal, Lesinski, Gregory B, Buchwald, Zachary S, Schmitt, Nicole C
Publicado 2023

Genetically engineered murine pancreatic cancer models approximate immunophenotypic properties of human patients

por Mace, Thomas A, Pitaressi, Jason, Shakya, Reena, Frankel, Wendy, Eubank, Tim, Bekaii-Saab, Tanios, Bloomston, Mark, Phelps, Mitch, Ludwig, Thomas, Ostrowski, Michael, Lesinski, Gregory B
Publicado 2013

Laser Capture Microdissection of Pancreatic Acinar Cells to Identify Proteomic Alterations in a Murine Model of Caerulein-Induced Pancreatitis

por Shapiro, John P, Komar, Hannah M, Hancioglu, Baris, Yu, Lianbo, Jin, Ming, Ogata, Yuko, Hart, Phil A, Cruz-Monserrate, Zobeida, Lesinski, Gregory B, Conwell, Darwin L
Publicado 2017

A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells

por Lin, Li, Deangelis, Stephanie, Foust, Elizabeth, Fuchs, James, Li, Chenglong, Li, Pui-Kai, Schwartz, Eric B, Lesinski, Gregory B, Benson, Don, Lü, Jiagao, Hoyt, Dale, Lin, Jiayuh
Publicado 2010

Ultraviolet Light B-Mediated Inhibition of Skin Catalase Activity Promotes Gr-1(+)CD11b(+) Myeloid Cell Expansion

por Sullivan, Nicholas J., Tober, Kathleen L., Burns, Erin M., Schick, Jonathan S., Riggenbach, Judith A., Mace, Thomas A., Bill, Matthew A., Young, Gregory S., Oberyszyn, Tatiana M., Lesinski, Gregory B.
Publicado 2011

A Phase I Study of High-Dose Interleukin-2 With Sorafenib in Patients With Metastatic Renal Cell Carcinoma and Melanoma

por Monk, Paul, Lam, Elaine, Mortazavi, Amir, Kendra, Kari, Lesinski, Gregory B., Mace, Thomas A., Geyer, Susan, Carson, William E., Tahiri, Sanaa, Bhinder, Arvinder, Clinton, Steven K., Olencki, Thomas
Publicado 2014

Novel Small Molecule XPO1/CRM1 Inhibitors Induce Nuclear Accumulation of TP53, Phosphorylated MAPK and Apoptosis in Human Melanoma Cells

por Yang, Jennifer, Bill, Matthew A., Young, Gregory S., La Perle, Krista, Landesman, Yosef, Shacham, Sharon, Kauffman, Michael, Senapedis, William, Kashyap, Trinayan, Saint-Martin, Jean-Richard, Kendra, Kari, Lesinski, Gregory B.
Publicado 2014

PRMT5 Is Upregulated in Malignant and Metastatic Melanoma and Regulates Expression of MITF and p27(Kip1)

por Nicholas, Courtney, Yang, Jennifer, Peters, Sara B., Bill, Matthew A., Baiocchi, Robert A., Yan, Fengting, Sïf, Saïd, Tae, Sookil, Gaudio, Eugenio, Wu, Xin, Grever, Michael R., Young, Gregory S., Lesinski, Gregory B.
Publicado 2013

Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 signaling in genetically engineered mice with pancreatic cancer

por Mace, Thomas A., Shakya, Reena, Elnaggar, Omar, Wilson, Kristin, Komar, Hannah M., Yang, Jennifer, Pitarresi, Jason R., Young, Gregory S., Ostrowski, Michael C., Ludwig, Thomas, Bekaii-Saab, Tanios, Bloomston, Mark, Lesinski, Gregory B.
Publicado 2015