The JCSG high-throughput structural biology pipeline

por Elsliger, Marc-André, Deacon, Ashley M., Godzik, Adam, Lesley, Scott A., Wooley, John, Wüthrich, Kurt, Wilson, Ian A.
Publicado 2010

An unusual mechanism of thymidylate biosynthesis in organisms containing the thyX Gene

por Koehn, Eric M., Fleischmann, Todd, Conrad, John A., Palfey, Bruce A., Lesley, Scott A., Mathews, Irimpan I., Kohen, Amnon
Publicado 2009

Crystal Structure of a Two-Subunit TrkA Octameric Gating Ring Assembly

por Deller, Marc C., Johnson, Hope A., Miller, Mitchell D., Spraggon, Glen, Elsliger, Marc-André, Wilson, Ian A., Lesley, Scott A.
Publicado 2015

Structural Insights into the Recognition of Phosphopeptide by the FHA Domain of Kanadaptin

por Xu, Qingping, Deller, Marc C., Nielsen, Tine K., Grant, Joanna C., Lesley, Scott A., Elsliger, Marc-André, Deacon, Ashley M., Wilson, Ian A.
Publicado 2014

Crystal Structure and Activity Studies of the C11 Cysteine Peptidase from Parabacteroides merdae in the Human Gut Microbiome

por McLuskey, Karen, Grewal, Jaspreet S., Das, Debanu, Godzik, Adam, Lesley, Scott A., Deacon, Ashley M., Coombs, Graham H., Elsliger, Marc-André, Wilson, Ian A., Mottram, Jeremy C.
Publicado 2016

Structural Analysis of Papain-Like NlpC/P60 Superfamily Enzymes with a Circularly Permuted Topology Reveals Potential Lipid Binding Sites

por Xu, Qingping, Rawlings, Neil D., Chiu, Hsiu-Ju, Jaroszewski, Lukasz, Klock, Heath E., Knuth, Mark W., Miller, Mitchell D., Elsliger, Marc-Andre, Deacon, Ashley M., Godzik, Adam, Lesley, Scott A., Wilson, Ian A.
Publicado 2011

Structure of an MmyB-Like Regulator from C. aurantiacus, Member of a New Transcription Factor Family Linked to Antibiotic Metabolism in Actinomycetes

por Xu, Qingping, van Wezel, Gilles P., Chiu, Hsiu-Ju, Jaroszewski, Lukasz, Klock, Heath E., Knuth, Mark W., Miller, Mitchell D., Lesley, Scott A., Godzik, Adam, Elsliger, Marc-André, Deacon, Ashley M., Wilson, Ian A.
Publicado 2012

Correction: Structure of an MmyB-Like Regulator from C. aurantiacus, Member of a New Transcription Factor Family Linked to Antibiotic Metabolism in Actinomycetes

por Xu, Qingping, van Wezel, Gilles P., Chiu, Hsiu-Ju, Jaroszewski, Lukasz, Klock, Heath E., Knuth, Mark W., Miller, Mitchell D., Lesley, Scott A., Godzik, Adam, Elsliger, Marc-André, Deacon, Ashley M., Wilson, Ian A.
Publicado 2012

Structure and Function of the First Full-Length Murein Peptide Ligase (Mpl) Cell Wall Recycling Protein

por Das, Debanu, Hervé, Mireille, Feuerhelm, Julie, Farr, Carol L., Chiu, Hsiu-Ju, Elsliger, Marc-André, Knuth, Mark W., Klock, Heath E., Miller, Mitchell D., Godzik, Adam, Lesley, Scott A., Deacon, Ashley M., Mengin-Lecreulx, Dominique, Wilson, Ian A.
Publicado 2011

Insights into Substrate Specificity of NlpC/P60 Cell Wall Hydrolases Containing Bacterial SH3 Domains

por Xu, Qingping, Mengin-Lecreulx, Dominique, Liu, Xueqian W., Patin, Delphine, Farr, Carol L., Grant, Joanna C., Chiu, Hsiu-Ju, Jaroszewski, Lukasz, Knuth, Mark W., Godzik, Adam, Lesley, Scott A., Elsliger, Marc-André, Deacon, Ashley M., Wilson, Ian A.
Publicado 2015

Structural and Sequence Analysis of Imelysin-Like Proteins Implicated in Bacterial Iron Uptake

por Xu, Qingping, Rawlings, Neil D., Farr, Carol L., Chiu, Hsiu-Ju, Grant, Joanna C., Jaroszewski, Lukasz, Klock, Heath E., Knuth, Mark W., Miller, Mitchell D., Weekes, Dana, Elsliger, Marc-André, Deacon, Ashley M., Godzik, Adam, Lesley, Scott A., Wilson, Ian A.
Publicado 2011

Structure of a Novel Winged-Helix Like Domain from Human NFRKB Protein

por Kumar, Abhinav, Möcklinghoff, Sabine, Yumoto, Fumiaki, Jaroszewski, Lukasz, Farr, Carol L., Grzechnik, Anna, Nguyen, Phuong, Weichenberger, Christian X., Chiu, Hsiu-Ju, Klock, Heath E., Elsliger, Marc-André, Deacon, Ashley M., Godzik, Adam, Lesley, Scott A., Conklin, Bruce R., Fletterick, Robert J., Wilson, Ian A.
Publicado 2012

A Human IgSF Cell-Surface Interactome Reveals a Complex Network of Protein-Protein Interactions

por Wojtowicz, Woj M., Vielmetter, Jost, Fernandes, Ricardo A., Siepe, Dirk H., Eastman, Catharine L., Chisholm, Gregory B., Cox, Sarah, Klock, Heath, Anderson, Paul W., Rue, Sarah M., Miller, Jessica J., Glaser, Scott M., Bragstad, Melisa L., Vance, Julie, Lam, Annie W., Lesley, Scott A., Zinn, Kai, Garcia, K. Christopher
Publicado 2020

Structure of an essential bacterial protein YeaZ (TM0874) from Thermotoga maritima at 2.5 Å resolution

por Xu, Qingping, McMullan, Daniel, Jaroszewski, Lukasz, Krishna, S. Sri, Elsliger, Marc-André, Yeh, Andrew P., Abdubek, Polat, Astakhova, Tamara, Axelrod, Herbert L., Carlton, Dennis, Chiu, Hsiu-Ju, Clayton, Thomas, Duan, Lian, Feuerhelm, Julie, Grant, Joanna, Han, Gye Won, Jin, Kevin K., Klock, Heath E., Knuth, Mark W., Miller, Mitchell D., Morse, Andrew T., Nigoghossian, Edward, Okach, Linda, Oommachen, Silvya, Paulsen, Jessica, Reyes, Ron, Rife, Christopher L., van den Bedem, Henry, Hodgson, Keith O., Wooley, John, Deacon, Ashley M., Godzik, Adam, Lesley, Scott A., Wilson, Ian A.
Publicado 2009

The structure of SSO2064, the first representative of Pfam family PF01796, reveals a novel two-domain zinc-ribbon OB-fold architecture with a potential acyl-CoA-binding role

por Krishna, S. Sri, Aravind, L., Bakolitsa, Constantina, Caruthers, Jonathan, Carlton, Dennis, Miller, Mitchell D., Abdubek, Polat, Astakhova, Tamara, Axelrod, Herbert L, Chiu, Hsiu-Ju, Clayton, Thomas, Deller, Marc C., Duan, Lian, Feuerhelm, Julie, Grant, Joanna C., Han, Gye Won, Jaroszewski, Lukasz, Jin, Kevin K., Klock, Heath E., Knuth, Mark W., Kumar, Abhinav, Marciano, David, McMullan, Daniel, Morse, Andrew T., Nigoghossian, Edward, Okach, Linda, Reyes, Ron, Rife, Christopher L., van den Bedem, Henry, Weekes, Dana, Xu, Qingping, Hodgson, Keith O., Wooley, John, Elsliger, Marc-André, Deacon, Ashley M., Godzik, Adam, Lesley, Scott A., Wilson, Ian A.
Publicado 2010

Structure of the first representative of Pfam family PF04016 (DUF364) reveals enolase and Rossmann-like folds that combine to form a unique active site with a possible role in heav...

por Miller, Mitchell D., Aravind, L., Bakolitsa, Constantina, Rife, Christopher L., Carlton, Dennis, Abdubek, Polat, Astakhova, Tamara, Axelrod, Herbert L., Chiu, Hsiu-Ju, Clayton, Thomas, Deller, Marc C., Duan, Lian, Feuerhelm, Julie, Grant, Joanna C., Han, Gye Won, Jaroszewski, Lukasz, Jin, Kevin K., Klock, Heath E., Knuth, Mark W., Kozbial, Piotr, Krishna, S. Sri, Kumar, Abhinav, Marciano, David, McMullan, Daniel, Morse, Andrew T., Nigoghossian, Edward, Okach, Linda, Reyes, Ron, van den Bedem, Henry, Weekes, Dana, Xu, Qingping, Hodgson, Keith O., Wooley, John, Elsliger, Marc-André, Deacon, Ashley M., Godzik, Adam, Lesley, Scott A., Wilson, Ian A.
Publicado 2010

Structure of the first representative of Pfam family PF09410 (DUF2006) reveals a structural signature of the calycin superfamily that suggests a role in lipid metabolism

por Chiu, Hsiu-Ju, Bakolitsa, Constantina, Skerra, Arne, Lomize, Andrei, Carlton, Dennis, Miller, Mitchell D., Krishna, S. Sri, Abdubek, Polat, Astakhova, Tamara, Axelrod, Herbert L., Clayton, Thomas, Deller, Marc C., Duan, Lian, Feuerhelm, Julie, Grant, Joanna C., Grzechnik, Slawomir K., Han, Gye Won, Jaroszewski, Lukasz, Jin, Kevin K., Klock, Heath E., Knuth, Mark W., Kozbial, Piotr, Kumar, Abhinav, Marciano, David, McMullan, Daniel, Morse, Andrew T., Nigoghossian, Edward, Okach, Linda, Paulsen, Jessica, Reyes, Ron, Rife, Christopher L., van den Bedem, Henry, Weekes, Dana, Xu, Qingping, Hodgson, Keith O., Wooley, John, Elsliger, Marc-André, Deacon, Ashley M., Godzik, Adam, Lesley, Scott A., Wilson, Ian A.
Publicado 2009

The structure of Haemophilus influenzae prephenate dehydrogenase suggests unique features of bifunctional TyrA enzymes

por Chiu, Hsiu-Ju, Abdubek, Polat, Astakhova, Tamara, Axelrod, Herbert L., Carlton, Dennis, Clayton, Thomas, Das, Debanu, Deller, Marc C., Duan, Lian, Feuerhelm, Julie, Grant, Joanna C., Grzechnik, Anna, Han, Gye Won, Jaroszewski, Lukasz, Jin, Kevin K., Klock, Heath E., Knuth, Mark W., Kozbial, Piotr, Krishna, S. Sri, Kumar, Abhinav, Marciano, David, McMullan, Daniel, Miller, Mitchell D., Morse, Andrew T., Nigoghossian, Edward, Okach, Linda, Reyes, Ron, Tien, Henry J., Trame, Christine B., van den Bedem, Henry, Weekes, Dana, Xu, Qingping, Hodgson, Keith O., Wooley, John, Elsliger, Marc-André, Deacon, Ashley M., Godzik, Adam, Lesley, Scott A., Wilson, Ian A.
Publicado 2010

Structure of LP2179, the first representative of Pfam family PF08866, suggests a new fold with a role in amino-acid metabolism

por Bakolitsa, Constantina, Kumar, Abhinav, Carlton, Dennis, Miller, Mitchell D., Krishna, S. Sri, Abdubek, Polat, Astakhova, Tamara, Axelrod, Herbert L., Chiu, Hsiu-Ju, Clayton, Thomas, Deller, Marc C., Duan, Lian, Elsliger, Marc-André, Feuerhelm, Julie, Grzechnik, Slawomir K., Grant, Joanna C., Han, Gye Won, Jaroszewski, Lukasz, Jin, Kevin K., Klock, Heath E., Knuth, Mark W., Kozbial, Piotr, Marciano, David, McMullan, Daniel, Morse, Andrew T., Nigoghossian, Edward, Okach, Linda, Oommachen, Silvya, Paulsen, Jessica, Reyes, Ron, Rife, Christopher L., Tien, Henry J., Trout, Christina V., van den Bedem, Henry, Weekes, Dana, Xu, Qingping, Hodgson, Keith O., Wooley, John, Deacon, Ashley M., Godzik, Adam, Lesley, Scott A., Wilson, Ian A.
Publicado 2009

The structure of the first representative of Pfam family PF06475 reveals a new fold with possible involvement in glycolipid metabolism

por Bakolitsa, Constantina, Kumar, Abhinav, McMullan, Daniel, Krishna, S. Sri, Miller, Mitchell D., Carlton, Dennis, Najmanovich, Rafael, Abdubek, Polat, Astakhova, Tamara, Chiu, Hsiu-Ju, Clayton, Thomas, Deller, Marc C., Duan, Lian, Elias, Ylva, Feuerhelm, Julie, Grant, Joanna C., Grzechnik, Slawomir K., Han, Gye Won, Jaroszewski, Lukasz, Jin, Kevin K., Klock, Heath E., Knuth, Mark W., Kozbial, Piotr, Marciano, David, Morse, Andrew T., Nigoghossian, Edward, Okach, Linda, Oommachen, Silvya, Paulsen, Jessica, Reyes, Ron, Rife, Christopher L., Trout, Christina V., van den Bedem, Henry, Weekes, Dana, White, Aprilfawn, Xu, Qingping, Hodgson, Keith O., Wooley, John, Elsliger, Marc-André, Deacon, Ashley M., Godzik, Adam, Lesley, Scott A., Wilson, Ian A.
Publicado 2009