Development of a Corneal Bioluminescence Mouse for Real-Time In Vivo Evaluation of Gene Therapies

por Fu, Dun Jack, Allen, Edwin H. A., Hickerson, Robyn P., Leslie Pedrioli, Deena M., McLean, W. H. Irwin
Publicado 2020

In vivo gene silencing following non-invasive siRNA delivery into the skin using a novel topical formulation

por Hegde, Vikas, Hickerson, Robyn P., Nainamalai, Sitheswaran, Campbell, Paul A., Smith, Frances J.D., McLean, W.H. Irwin, Leslie Pedrioli, Deena M.
Publicado 2014

Absence of mitochondrial SLC25A51 enhances PARP1-dependent DNA repair by increasing nuclear NAD(+) levels

por Güldenpfennig, Anka, Hopp, Ann-Katrin, Muskalla, Lukas, Manetsch, Patrick, Raith, Fabio, Hellweg, Lars, Dördelmann, Cyril, Leslie Pedrioli, Deena M, Johnsson, Kai, Superti-Furga, Giulio, Hottiger, Michael O
Publicado 2023

Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins

por Nowak, Kathrin, Rosenthal, Florian, Karlberg, Tobias, Bütepage, Mareike, Thorsell, Ann-Gerd, Dreier, Birgit, Grossmann, Jonas, Sobek, Jens, Imhof, Ralph, Lüscher, Bernhard, Schüler, Herwig, Plückthun, Andreas, Leslie Pedrioli, Deena M., Hottiger, Michael O.
Publicado 2020

Tankyrase-mediated ADP-ribosylation is a regulator of TNF-induced death

por Liu, Lin, Sandow, Jarrod J., Leslie Pedrioli, Deena M., Samson, Andre L., Silke, Natasha, Kratina, Tobias, Ambrose, Rebecca L., Doerflinger, Marcel, Hu, Zhaoqing, Morrish, Emma, Chau, Diep, Kueh, Andrew J., Fitzibbon, Cheree, Pellegrini, Marc, Pearson, Jaclyn S., Hottiger, Michael O., Webb, Andrew I., Lalaoui, Najoua, Silke, John
Publicado 2022

Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy

por Allen, Edwin H.A., Courtney, David G., Atkinson, Sarah D., Moore, Johnny E., Mairs, Laura, Poulsen, Ebbe Toftgaard, Schiroli, Davide, Maurizi, Eleonora, Cole, Christian, Hickerson, Robyn P., James, John, Murgatroyd, Helen, Smith, Frances J.D., MacEwen, Carrie, Enghild, Jan J., Nesbit, M. Andrew, Leslie Pedrioli, Deena M., McLean, W.H. Irwin, Moore, C.B. Tara
Publicado 2016