Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy Family Members With a Pathogenic NOTCH3 Variant Can Have a Normal Brain Magnetic Resonanc...

por Hack, Remco J., Gravesteijn, Gido, Cerfontaine, Minne N., Hegeman, Ingrid M., Mulder, Aat A., Lesnik Oberstein, Saskia A.J., Rutten, Julie W.
Publicado 2022

Cysteine-Altering NOTCH3 Variants Are a Risk Factor for Stroke in the Elderly Population

por Hack, Remco J., Rutten, Julie W., Person, Thomas N., Li, Jiang, Khan, Ayesha, Griessenauer, Christoph J., Abedi, Vida, Lesnik Oberstein, Saskia A.J., Zand, Ramin
Publicado 2020

Engineered 3D vessel-on-chip using hiPSC-derived endothelial- and vascular smooth muscle cells

por Vila Cuenca, Marc, Cochrane, Amy, van den Hil, Francijna E., de Vries, Antoine A.F., Lesnik Oberstein, Saskia A.J., Mummery, Christine L., Orlova, Valeria V.
Publicado 2021

Effect of NOTCH3 EGFr Group, Sex, and Cardiovascular Risk Factors on CADASIL Clinical and Neuroimaging Outcomes

por Hack, Remco J., Cerfontaine, Minne N., Gravesteijn, Gido, Tap, Stephan, Hafkemeijer, Anne, van der Grond, Jeroen, Witjes-Ané, Marie-Noëlle, Baas, Frank, Rutten, Julie W., Lesnik Oberstein, Saskia A.J.
Publicado 2022

Active immunotherapy reduces NOTCH3 deposition in brain capillaries in a CADASIL mouse model

por Oliveira, Daniel V, Coupland, Kirsten G, Shao, Wenchao, Jin, Shaobo, Del Gaudio, Francesca, Wang, Sailan, Fox, Rhys, Rutten, Julie W, Sandin, Johan, Zetterberg, Henrik, Lundkvist, Johan, Lesnik Oberstein, Saskia AJ, Lendahl, Urban, Karlström, Helena
Publicado 2022

Broad phenotype of cysteine-altering NOTCH3 variants in UK Biobank: CADASIL to nonpenetrance

por Rutten, Julie W., Hack, Remco J., Duering, Marco, Gravesteijn, Gido, Dauwerse, Johannes G., Overzier, Maurice, van den Akker, Erik B., Slagboom, Eline, Holstege, Henne, Nho, Kwangsik, Saykin, Andrew, Dichgans, Martin, Malik, Rainer, Lesnik Oberstein, Saskia A.J.
Publicado 2020