Update on ICH E14/S7B Cardiac Safety Regulations: The Expanded Role of Preclinical Assays and the “Double‐Negative” Scenario

por Lester, Robert M.
Publicado 2021

QT Assessment in Early Drug Development: The Long and the Short of It

por Lester, Robert M., Paglialunga, Sabina, Johnson, Ian A.
Publicado 2019

Evaluating cardiac risk: exposure response analysis in early clinical drug development

por Grenier, Julie, Paglialunga, Sabina, Morimoto, Bruce H, Lester, Robert M
Publicado 2018

Semi-automated segmentation of magnetic resonance images for thigh skeletal muscle and fat using threshold technique after spinal cord injury

por Ghatas, Mina P., Lester, Robert M., Khan, M. Rehan, Gorgey, Ashraf S.
Publicado 2018

MRI analysis and clinical significance of lower extremity muscle cross-sectional area after spinal cord injury

por Lester, Robert M., Johnson, Kori, Khalil, Refka E., Khan, Rehan, Gorgey, Ashraf S.
Publicado 2017

Dietary manipulation and testosterone replacement therapy may explain changes in body composition after spinal cord injury: A retrospective case report

por Gorgey, Ashraf S, Lester, Robert M, Ghatas, Mina P, Sistrun, Sakita N, Lavis, Timothy
Publicado 2019

Safety, Tolerability, Pharmacokinetics, and Concentration-QTc Analysis of Tetrodotoxin: A Randomized, Dose Escalation Study in Healthy Adults

por Kavoosi, Mojgan, O’Reilly, Terry E., Kavoosi, Mehran, Chai, Peng, Engel, Caroline, Korz, Walter, Gallen, Christopher C., Lester, Robert M.
Publicado 2020