RA-XII inhibits tumour growth and metastasis in breast tumour-bearing mice via reducing cell adhesion and invasion and promoting matrix degradation

por Leung, Hoi-Wing, Zhao, Si-Meng, Yue, Grace Gar-Lee, Lee, Julia Kin-Ming, Fung, Kwok-Pui, Leung, Ping-Chung, Tan, Ning-Hua, Lau, Clara Bik-San
Publicado 2015

Is Danggui Safe to be Taken by Breast Cancer Patients?—A Skepticism Finally Answered by Comprehensive Preclinical Evidence

por Yue, Grace Gar-Lee, Wong, Lok-Sze, Leung, Hoi-Wing, Gao, Si, Tsang, Julia Yuen-Shan, Lin, Zhi-Xiu, Law, Bonita Ka-Bo, Tse, Gary Man-Kit, Lau, Clara Bik-San
Publicado 2019

Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform

por Olsen, Andrea, Harpaz, Zachary, Ren, Christopher, Shneyderman, Anastasia, Veviorskiy, Alexander, Dralkina, Maria, Konnov, Simon, Shcheglova, Olga, Pun, Frank W., Leung, Geoffrey Ho Duen, Leung, Hoi Wing, Ozerov, Ivan V., Aliper, Alex, Korzinkin, Mikhail, Zhavoronkov, Alex
Publicado 2023

Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature importance analysis for aging and age-related disease target discovery

por Urban, Anatoly, Sidorenko, Denis, Zagirova, Diana, Kozlova, Ekaterina, Kalashnikov, Aleksandr, Pushkov, Stefan, Naumov, Vladimir, Sarkisova, Viktoria, Leung, Geoffrey Ho Duen, Leung, Hoi Wing, Pun, Frank W., Ozerov, Ivan V., Aliper, Alex, Ren, Feng, Zhavoronkov, Alex
Publicado 2023

Hallmarks of aging-based dual-purpose disease and age-associated targets predicted using PandaOmics AI-powered discovery engine

por Pun, Frank W., Leung, Geoffrey Ho Duen, Leung, Hoi Wing, Liu, Bonnie Hei Man, Long, Xi, Ozerov, Ivan V., Wang, Ju, Ren, Feng, Aliper, Alexander, Izumchenko, Evgeny, Moskalev, Alexey, de Magalhães, João Pedro, Zhavoronkov, Alex
Publicado 2022

Novel PI3K/AKT targeting anti-angiogenic activities of 4-vinylphenol, a new therapeutic potential of a well-known styrene metabolite

por Yue, Grace Gar-Lee, Lee, Julia Kin-Ming, Kwok, Hin-Fai, Cheng, Ling, Wong, Eric Chun-Wai, Jiang, Lei, Yu, Hua, Leung, Hoi-Wing, Wong, Yuk-Lau, Leung, Ping-Chung, Fung, Kwok-Pui, Lau, Clara Bik-San
Publicado 2015

The interplay of UBE2T and Mule in regulating Wnt/β-catenin activation to promote hepatocellular carcinoma progression

por Ho, Nicole Pui Yu, Leung, Carmen Oi Ning, Wong, Tin Lok, Lau, Eunice Yuen Ting, Lei, Martina Mang Leng, Mok, Etienne Ho Kit, Leung, Hoi Wing, Tong, Man, Ng, Irene Oi Lin, Yun, Jing Ping, Ma, Stephanie, Lee, Terence Kin Wah
Publicado 2021

Identification of Therapeutic Targets for Amyotrophic Lateral Sclerosis Using PandaOmics – An AI-Enabled Biological Target Discovery Platform

por Pun, Frank W., Liu, Bonnie Hei Man, Long, Xi, Leung, Hoi Wing, Leung, Geoffrey Ho Duen, Mewborne, Quinlan T., Gao, Junli, Shneyderman, Anastasia, Ozerov, Ivan V., Wang, Ju, Ren, Feng, Aliper, Alexander, Bischof, Evelyne, Izumchenko, Evgeny, Guan, Xiaoming, Zhang, Ke, Lu, Bai, Rothstein, Jeffrey D., Cudkowicz, Merit E., Zhavoronkov, Alex
Publicado 2022