Increased Expression of PITX2 Transcription Factor Contributes to Ovarian Cancer Progression

por Fung, Frederic K. C., Chan, David W., Liu, Vincent W. S., Leung, Thomas H. Y., Cheung, Annie N. Y., Ngan, Hextan Y. S.
Publicado 2012

Estrogen receptor modulators genistein, daidzein and ERB-041 inhibit cell migration, invasion, proliferation and sphere formation via modulation of FAK and PI3K/AKT signaling in ov...

por Chan, Karen K. L., Siu, Michelle K. Y., Jiang, Yu-xin, Wang, Jing-jing, Leung, Thomas H. Y., Ngan, Hextan Y. S.
Publicado 2018

Bitter Melon (Momordica charantia) Extract Inhibits Tumorigenicity and Overcomes Cisplatin-Resistance in Ovarian Cancer Cells Through Targeting AMPK Signaling Cascade

por Yung, Mingo M. H., Ross, Fiona A., Hardie, D. Grahame, Leung, Thomas H. Y., Zhan, Jinbiao, Ngan, Hextan Y. S., Chan, David W.
Publicado 2015

Aberrant Activation of ERK/FOXM1 Signaling Cascade Triggers the Cell Migration/Invasion in Ovarian Cancer Cells

por Lok, Gabriel T. M., Chan, David W., Liu, Vincent W. S., Hui, Winnie W. Y., Leung, Thomas H. Y., Yao, K. M., Ngan, Hextan Y. S.
Publicado 2011

PDK1 promotes ovarian cancer metastasis by modulating tumor-mesothelial adhesion, invasion, and angiogenesis via α5β1 integrin and JNK/IL-8 signaling

por Siu, Michelle K. Y., Jiang, Yu-xin, Wang, Jing-jing, Leung, Thomas H. Y., Ngu, Siew Fei, Cheung, Annie N. Y., Ngan, Hextan Y. S., Chan, Karen K. L.
Publicado 2020

PFKFB3 Regulates Chemoresistance, Metastasis and Stemness via IAP Proteins and the NF-κB Signaling Pathway in Ovarian Cancer

por Jiang, Yu-xin, Siu, Michelle K. Y., Wang, Jing-jing, Leung, Thomas H. Y., Chan, David W., Cheung, Annie N. Y., Ngan, Hextan Y. S., Chan, Karen K. L.
Publicado 2022

Differential expression of estrogen receptor subtypes and variants in ovarian cancer: effects on cell invasion, proliferation and prognosis

por Chan, Karen K. L., Siu, Michelle K. Y., Jiang, Yu-xin, Wang, Jing-jing, Wang, Yan, Leung, Thomas H. Y., Liu, Stephanie S., Cheung, Annie N. Y., Ngan, Hextan Y. S.
Publicado 2017

AMPK Activators Suppress Cervical Cancer Cell Growth through Inhibition of DVL3 Mediated Wnt/β-Catenin Signaling Activity

por Kwan, H. T., Chan, David W., Cai, Patty C. H., Mak, Celia S. L., Yung, Mingo M. H., Leung, Thomas H. Y., Wong, Oscar G. W., Cheung, Annie N. Y., Ngan, Hextan Y. S.
Publicado 2013

Hexokinase 2 Regulates Ovarian Cancer Cell Migration, Invasion and Stemness via FAK/ERK1/2/MMP9/NANOG/SOX9 Signaling Cascades

por Siu, Michelle K. Y., Jiang, Yu-Xin, Wang, Jing-Jing, Leung, Thomas H. Y., Han, Chae Young, Tsang, Benjamin K., Cheung, Annie N. Y., Ngan, Hextan Y. S., Chan, Karen K. L.
Publicado 2019

Targeting GRB7/ERK/FOXM1 Signaling Pathway Impairs Aggressiveness of Ovarian Cancer Cells

por Chan, David W., Hui, Winnie W. Y., Cai, Patty C. H., Liu, Michelle X., Yung, Mingo M. H., Mak, Celia S. L., Leung, Thomas H. Y., Chan, Karen K. L., Ngan, Hextan Y. S.
Publicado 2012

Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling

por Cai, Patty C.H., Shi, Lei, Liu, Vincent W.S., Tang, Hermit W.M., Liu, Iris J., Leung, Thomas H.Y., Chan, Karen K.L., Yam, Judy W.P., Yao, Kwok-Ming, Ngan, Hextan Y.S., Chan, David W.
Publicado 2014

MicroRNA-141 enhances anoikis resistance in metastatic progression of ovarian cancer through targeting KLF12/Sp1/survivin axis

por Mak, Celia S. L., Yung, Mingo M. H., Hui, Lynn M. N., Leung, Leanne L., Liang, Rui, Chen, Kangmei, Liu, Stephanie S., Qin, Yiming, Leung, Thomas H. Y., Lee, Kai-Fai, Chan, Karen K. L., Ngan, Hextan Y. S., Chan, David W.
Publicado 2017

Targeting of lipid metabolism with a metabolic inhibitor cocktail eradicates peritoneal metastases in ovarian cancer cells

por Chen, Rain R., Yung, Mingo M. H., Xuan, Yang, Zhan, Shijie, Leung, Leanne L., Liang, Rachel R., Leung, Thomas H. Y., Yang, Huijuan, Xu, Dakang, Sharma, Rakesh, Chan, Karen K. L., Ngu, Siew-Fei, Ngan, Hextan Y. S., Chan, David W.
Publicado 2019