Hyperglycemia alters retinoic acid catabolism in embryos exposed to a maternal diabetic milieu

por Lee, Leo Man Yuen, Leung, Yun-chung, Shum, Alisa Sau Wun
Publicado 2023

Interdomain flexibility and interfacial integrity of β-lactamase inhibitory protein (BLIP) modulate its binding to class A β-lactamases

por Huang, Liwen, So, Pui-Kin, Chen, Yu Wai, Leung, Yun-Chung, Yao, Zhong-Ping
Publicado 2021

Thermostable β-Lactamase Mutant with Its Active Site Conjugated with Fluorescein for Efficient β-Lactam Antibiotic Detection

por Au, Ho-Wah, Tsang, Man-Wah, So, Pui-Kin, Wong, Kwok-Yin, Leung, Yun-Chung
Publicado 2019

Structural studies of the mechanism for biosensing antibiotics in a fluorescein-labeled β-lactamase

por Wong, Wai-Ting, Au, Ho-Wah, Yap, Hong-Kin, Leung, Yun-Chung, Wong, Kwok-Yin, Zhao, Yanxiang
Publicado 2011

Effect of Lactamase Inhibitors on the Biosensor Penp during the Measurement of Lactam Antibiotics Concentration

por Soto, Dagoberto, Silva, Camila, Ugalde, Cristian, Wong, Kwok-Yin, Leung, Yun-Chung, So, Lok-Yan, Andresen, Max
Publicado 2019

Fluorescent TEM-1 β-lactamase with wild-type activity as a rapid drug sensor for in vitro drug screening

por Cheong, Wing-Lam, Tsang, Ming-San, So, Pui-Kin, Chung, Wai-Hong, Leung, Yun-Chung, Chan, Pak-Ho
Publicado 2014

Plasma and Renal Cortex Meropenem Concentrations in Patients Undergoing Percutaneous Renal Biopsy

por Sepúlveda, Rodrigo A., Downey, Patricio, Soto, Dagoberto, Wong, Kwok-Yin, Leung, Yun-Chung, So, Lok-Yan, Andresen, Max
Publicado 2019

BADAN-conjugated β-lactamases as biosensors for β-lactam antibiotic detection

por Au, Ho-Wah, Tsang, Man-Wah, Chen, Yu Wai, So, Pui-Kin, Wong, Kwok-Yin, Leung, Yun-Chung
Publicado 2020

Deprivation of arginine by recombinant human arginase in prostate cancer cells

por Hsueh, Eddy C, Knebel, Stephanie M, Lo, Wai-Hung, Leung, Yun-Chung, Cheng, Paul Ning-Man, Hsueh, Chung-Tsen
Publicado 2012

Mono-PEGylated thermostable Bacillus caldovelox arginase mutant (BCA-M-PEG20) induces apoptosis, autophagy, cell cycle arrest and growth inhibition in gastric cancer cells

por Chung, Sai-Fung, Tam, Suet-Ying, Kim, Chi-Fai, Chong, Hiu-Chi, Lee, Leo Man-Yuen, Leung, Yun-Chung
Publicado 2022

Arginine Is a Novel Drug Target for Arginine Decarboxylase in Human Colorectal Cancer Cells

por Wei, Xinlei, Chow, Ho-Yin, Chong, Hiu-Chi, Leung, Siu-Lun, Ho, Mei-Ki, Lee, Man-Yuen, Leung, Yun-Chung
Publicado 2023

The structural dynamics of full-length divisome transmembrane proteins FtsQ, FtsB, and FtsL in FtsQBL complex formation

por Kong, Wai-Po, Gong, Furong, So, Pui-Kin, Chen, Yu Wai, Chan, Pak-Ho, Leung, Yun-Chung, Wong, Kwok-Yin
Publicado 2022

Recombinant Bacillus caldovelox Arginase Mutant (BCA-M) Induces Apoptosis, Autophagy, Cell Cycle Arrest and Growth Inhibition in Human Cervical Cancer Cells

por Chung, Sai-Fung, Kim, Chi-Fai, Chow, Ho-Yin, Chong, Hiu-Chi, Tam, Suet-Ying, Leung, Yun-Chung, Lo, Wai-Hung
Publicado 2020

Efficient production of secretory Streptomyces clavuligerus β-lactamase inhibitory protein (BLIP) in Pichia pastoris

por Law, Kin-Ho, Tsang, Man-Wah, Wong, Yuk-Ki, Tsang, Ming-San, Lau, Pui-Yee, Wong, Kwok-Yin, Ho, Kwok-Ping, Leung, Yun-Chung
Publicado 2018

Functionalized quinolizinium-based fluorescent reagents for modification of cysteine-containing peptides and proteins

por Kung, Karen Ka-Yan, Xu, Cai-fung, O, Wa-Yi, Yu, Qiong, Chung, Sai-Fung, Tam, Suet-Ying, Leung, Yun-Chung, Wong, Man-Kin
Publicado 2022

Rational structural modification of the isatin scaffold to develop new and potent antimicrobial agents targeting bacterial peptidoglycan glycosyltransferase

por Wang, Yong, Liang, Zhiguang, Zheng, Yuanyuan, Leung, Alan Siu-Lun, Yan, Siu-Cheong, So, Pui-Kin, Leung, Yun-Chung, Wong, Wing-Leung, Wong, Kwok-Yin
Publicado 2021

Evaluation of Meropenem Pharmacokinetics in an Experimental Acute Respiratory Distress Syndrome (ARDS) Model during Extracorporeal Membrane Oxygenation (ECMO) by Using a PenP β-Lac...

por Andresen, Max, Araos, Joaquin, Wong, Kwok-Yin, Leung, Yun-Chung, So, Lok-Yan, Wong, Wai-Ting, Cabrera, Salvador, Silva, Camila, Alegria, Leyla, Bruhn, Alejandro, Soto, Dagoberto
Publicado 2018

Method Based on the β-Lactamase PenPC Fluorescent Labeled for β-Lactam Antibiotic Quantification in Human Plasma

por Andresen, Max, Wong, Kwok-Yin, Leung, Yun-Chung, Wong, Wai-Ting, Chan, Pak-Ho, Andresen-Vasquez, Max, Alegria, Leyla, Silva, Camila, Tapia, Pablo, Downey, Patricio, Soto, Dagoberto
Publicado 2016

A Thiazole Orange Derivative Targeting the Bacterial Protein FtsZ Shows Potent Antibacterial Activity

por Sun, Ning, Lu, Yu-Jing, Chan, Fung-Yi, Du, Ruo-Lan, Zheng, Yuan-yuan, Zhang, Kun, So, Lok-Yan, Abagyan, Ruben, Zhuo, Chao, Leung, Yun-Chung, Wong, Kwok-Yin
Publicado 2017

N-Terminal selective modification of peptides and proteins using 2-ethynylbenzaldehydes

por Deng, Jie-Ren, Lai, Nathanael Chun-Him, Kung, Karen Ka-Yan, Yang, Bin, Chung, Sai-Fung, Leung, Alan Siu-Lun, Choi, Man-Chung, Leung, Yun-Chung, Wong, Man-Kin
Publicado 2020