Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes

por Watters, Kyle E., Shivram, Haridha, Fellmann, Christof, Lew, Rachel J., McMahon, Blake, Doudna, Jennifer A.
Publicado 2020

Endogenous spacing enables co-processing of microRNAs and efficient combinatorial RNAi

por Amen, Alexandra M., Loughran, Ryan M., Huang, Chun-Hao, Lew, Rachel J., Ravi, Archna, Guan, Yuanzhe, Schatoff, Emma M., Dow, Lukas E., Emerling, Brooke M., Fellmann, Christof
Publicado 2022

Site-Specific Bioconjugation through Enzyme-Catalyzed Tyrosine–Cysteine Bond Formation

por Lobba, Marco J., Fellmann, Christof, Marmelstein, Alan M., Maza, Johnathan C., Kissman, Elijah N., Robinson, Stephanie A., Staahl, Brett T., Urnes, Cole, Lew, Rachel J., Mogilevsky, Casey S., Doudna, Jennifer A., Francis, Matthew B.
Publicado 2020

Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage

por Amen, Alexandra M., Fellmann, Christof, Soczek, Katarzyna M., Ren, Shawn M., Lew, Rachel J., Knott, Gavin J., Park, Jesslyn E., McKinney, Andrew M., Mancini, Andrew, Doudna, Jennifer A., Costello, Joseph F.
Publicado 2021

Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a

por Knott, Gavin J, Cress, Brady F, Liu, Jun-Jie, Thornton, Brittney W, Lew, Rachel J, Al-Shayeb, Basem, Rosenberg, Daniel J, Hammel, Michal, Adler, Benjamin A, Lobba, Marco J, Xu, Michael, Arkin, Adam P, Fellmann, Christof, Doudna, Jennifer A
Publicado 2019

CRISPR–Cas9-mediated nuclear transport and genomic integration of nanostructured genes in human primary cells

por Lin-Shiao, Enrique, Pfeifer, Wolfgang G, Shy, Brian R, Saffari Doost, Mohammad, Chen, Evelyn, Vykunta, Vivasvan S, Hamilton, Jennifer R, Stahl, Elizabeth C, Lopez, Diana M, Sandoval Espinoza, Cindy R, Deyanov, Alexander E, Lew, Rachel J, Poirer, Michael G, Marson, Alexander, Castro, Carlos E, Doudna, Jennifer A
Publicado 2022