MicroRNAs in mouse development and disease

por Lewis, Morag A., Steel, Karen P.
Publicado 2010

Specific expression of Kcna10, Pxn and Odf2 in the organ of Corti

por Carlisle, Francesca A., Steel, Karen P., Lewis, Morag A.
Publicado 2012

Investigating the characteristics of genes and variants associated with self-reported hearing difficulty in older adults in the UK Biobank

por Lewis, Morag A., Schulte, Bradley A., Dubno, Judy R., Steel, Karen P.
Publicado 2022

Hearing impairment due to Mir183/96/182 mutations suggests both loss-of-function and gain-of-function effects

por Lewis, Morag A., Di Domenico, Francesca, Ingham, Neil J., Prosser, Haydn M., Steel, Karen P.
Publicado 2021

A missense mutation in Fgfr1 causes ear and skull defects in hush puppy mice

por Calvert, Jennifer A., Dedos, Skarlatos G., Hawker, Kelvin, Fleming, Michelle, Lewis, Morag A., Steel, Karen P.
Publicado 2011

Grxcr1 regulates hair bundle morphogenesis and is required for normal mechanoelectrical transduction in mouse cochlear hair cells

por Lorente-Cánovas, Beatriz, Eckrich, Stephanie, Lewis, Morag A., Johnson, Stuart L., Marcotti, Walter, Steel, Karen P.
Publicado 2022

A reduction in Ptprq associated with specific features of the deafness phenotype of the miR-96 mutant mouse diminuendo

por Chen, Jing, Johnson, Stuart L, Lewis, Morag A, Hilton, Jennifer M, Huma, Andreea, Marcotti, Walter, Steel, Karen P
Publicado 2014

Inner hair cell dysfunction in Klhl18 mutant mice leads to low frequency progressive hearing loss

por Ingham, Neil J., Banafshe, Navid, Panganiban, Clarisse, Crunden, Julia L., Chen, Jing, Lewis, Morag A., Steel, Karen P.
Publicado 2021

Functional analysis of candidate genes from genome-wide association studies of hearing

por Ingham, Neil J., Rook, Victoria, Di Domenico, Francesca, James, Elysia, Lewis, Morag A., Girotto, Giorgia, Buniello, Annalisa, Steel, Karen P.
Publicado 2020

Exome sequencing identifies a missense mutation in Isl1 associated with low penetrance otitis media in dearisch mice

por Hilton, Jennifer M, Lewis, Morag A, Grati, M'hamed, Ingham, Neil, Pearson, Selina, Laskowski, Roman A, Adams, David J, Steel, Karen P
Publicado 2011

Alternative Splice Forms Influence Functions of Whirlin in Mechanosensory Hair Cell Stereocilia

por Ebrahim, Seham, Ingham, Neil J., Lewis, Morag A., Rogers, Michael J.C., Cui, Runjia, Kachar, Bechara, Pass, Johanna C., Steel, Karen P.
Publicado 2016

Whole exome sequencing in adult-onset hearing loss reveals a high load of predicted pathogenic variants in known deafness-associated genes and identifies new candidate genes

por Lewis, Morag A., Nolan, Lisa S., Cadge, Barbara A., Matthews, Lois J., Schulte, Bradley A., Dubno, Judy R., Steel, Karen P., Dawson, Sally J.
Publicado 2018

Exploring regulatory networks of miR-96 in the developing inner ear

por Lewis, Morag A., Buniello, Annalisa, Hilton, Jennifer M., Zhu, Fei, Zhang, William I., Evans, Stephanie, van Dongen, Stijn, Enright, Anton J., Steel, Karen P.
Publicado 2016

In-depth genetic and molecular characterization of diaphanous related formin 2 (DIAPH2) and its role in the inner ear

por Chiereghin, Chiara, Robusto, Michela, Lewis, Morag A., Caetano, Susana, Massa, Valentina, Castorina, Pierangela, Ambrosetti, Umberto, Steel, Karen P., Duga, Stefano, Asselta, Rosanna, Soldà, Giulia
Publicado 2023

Accurate phenotypic classification and exome sequencing allow identification of novel genes and variants associated with adult-onset hearing loss

por Lewis, Morag A., Schulte, Jennifer, Matthews, Lois, Vaden, Kenneth I., Steves, Claire J., Williams, Frances M.K., Schulte, Bradley A., Dubno, Judy R., Steel, Karen P.
Publicado 2023

Translational and interdisciplinary insights into presbyacusis: A multidimensional disease

por Eckert, Mark A., Harris, Kelly C., Lang, Hainan, Lewis, Morag A., Schmiedt, Richard A., Schulte, Bradley A., Steel, Karen P., Vaden, Kenneth I., Dubno, Judy R.
Publicado 2021

Insights into the pathophysiology of DFNA44 hearing loss associated with CCDC50 frameshift variants

por Lachgar-Ruiz, María, Morín, Matías, Martelletti, Elisa, Ingham, Neil J., Preite, Lorenzo, Lewis, Morag A., Serrão de Castro, Luciana Santos, Steel, Karen P., Moreno-Pelayo, Miguel Ángel
Publicado 2023

S1PR2 variants associated with auditory function in humans and endocochlear potential decline in mouse

por Ingham, Neil J., Carlisle, Francesca, Pearson, Selina, Lewis, Morag A., Buniello, Annalisa, Chen, Jing, Isaacson, Rivka L., Pass, Johanna, White, Jacqueline K., Dawson, Sally J., Steel, Karen P.
Publicado 2016

OSBPL2 encodes a protein of inner and outer hair cell stereocilia and is mutated in autosomal dominant hearing loss (DFNA67)

por Thoenes, Michaela, Zimmermann, Ulrike, Ebermann, Inga, Ptok, Martin, Lewis, Morag A, Thiele, Holger, Morlot, Susanne, Hess, Markus M, Gal, Andreas, Eisenberger, Tobias, Bergmann, Carsten, Nürnberg, Gudrun, Nürnberg, Peter, Steel, Karen P, Knipper, Marlies, Bolz, Hanno Jörn
Publicado 2015

An ENU-induced mutation of miR-96 associated with progressive hearing loss in mice

por Lewis, Morag A, Quint, Elizabeth, Glazier, Anne M, Fuchs, Helmut, De Angelis, Martin Hrabé, Langford, Cordelia, van Dongen, Stijn, Abreu-Goodger, Cei, Piipari, Matias, Redshaw, Nick, Dalmay, Tamas, Pelayo, Miguel Angel Moreno, Enright, Anton J, Steel, Karen P
Publicado 2009