Poisoning the “histone code” in pediatric gliomagenesis

por Lewis, Peter W, Allis, C David
Publicado 2013

Human spliceosomal snRNA sequence variants generate variant spliceosomes

por Mabin, Justin W., Lewis, Peter W., Brow, David A., Dvinge, Heidi
Publicado 2021

Structural and mechanistic insights into ATRX-dependent and -independent functions of the histone chaperone DAXX

por Hoelper, Dominik, Huang, Hongda, Jain, Aayushi Y., Patel, Dinshaw J., Lewis, Peter W.
Publicado 2017

Strategy for “Detoxification” of a Cancer-Derived Histone Mutant Based on Mapping Its Interaction with the Methyltransferase PRC2

por Brown, Zachary Z., Müller, Manuel M., Jain, Siddhant U., Allis, C. David, Lewis, Peter W., Muir, Tom W.
Publicado 2014

ATRX links atypical histone methylation recognition mechanisms to human brain function

por Iwase, Shigeki, Xiang, Bin, Ghosh, Sharmistha, Ren, Ting, Lewis, Peter W., Cochrane, Jesse C., Allis, C. David, Picketts, David J., Patel, Dinshaw J., Li, Haitao, Shi, Yang
Publicado 2011

A sensitive and specific histopathologic prognostic marker for H3F3A K27M mutant pediatric glioblastomas

por Venneti, Sriram, Santi, Mariarita, Felicella, Michelle Madden, Yarilin, Dmitry, Phillips, Joanna J., Sullivan, Lisa M., Martinez, Daniel, Perry, Arie, Lewis, Peter W., Thompson, Craig B., Judkins, Alexander R.
Publicado 2014

ATRX, DAXX or MEN1 mutant pancreatic neuroendocrine tumors are a distinct alpha-cell signature subgroup

por Chan, Chang S., Laddha, Saurabh V., Lewis, Peter W., Koletsky, Matthew S., Robzyk, Kenneth, Da Silva, Edaise, Torres, Paula J., Untch, Brian R., Li, Janet, Bose, Promita, Chan, Timothy A., Klimstra, David S., Allis, C. David, Tang, Laura H.
Publicado 2018

PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism

por Jain, Siddhant U., Do, Truman J., Lund, Peder J., Rashoff, Andrew Q., Diehl, Katharine L., Cieslik, Marcin, Bajic, Andrea, Juretic, Nikoleta, Deshmukh, Shriya, Venneti, Sriram, Muir, Tom W., Garcia, Benjamin A., Jabado, Nada, Lewis, Peter W.
Publicado 2019

Specific detection of methionine 27 mutation in histone 3 variants (H3K27M) in fixed tissue from high-grade astrocytomas

por Bechet, Denise, Gielen, Gerrit G. H., Korshunov, Andrey, Pfister, Stefan M., Rousso, Caterina, Faury, Damien, Fiset, Pierre-Olivier, Benlimane, Naciba, Lewis, Peter W., Lu, Chao, David Allis, C., Kieran, Mark W., Ligon, Keith L., Pietsch, Torsten, Ellezam, Benjamin, Albrecht, Steffen, Jabado, Nada
Publicado 2014

Pathogenic human variant that dislocates GATA2 zinc fingers disrupts hematopoietic gene expression and signaling networks

por Jung, Mabel Minji, Shen, Siqi, Botten, Giovanni A., Olender, Thomas, Katsumura, Koichi R., Johnson, Kirby D., Soukup, Alexandra A., Liu, Peng, Zhang, Qingzhou, Jensvold, Zena D., Lewis, Peter W., Beagrie, Robert A., Low, Jason K.K., Yang, Lihua, Mackay, Joel P., Godley, Lucy A., Brand, Marjorie, Xu, Jian, Keles, Sunduz, Bresnick, Emery H.
Publicado 2023

H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis

por Harutyunyan, Ashot S., Krug, Brian, Chen, Haifen, Papillon-Cavanagh, Simon, Zeinieh, Michele, De Jay, Nicolas, Deshmukh, Shriya, Chen, Carol C. L., Belle, Jad, Mikael, Leonie G., Marchione, Dylan M., Li, Rui, Nikbakht, Hamid, Hu, Bo, Cagnone, Gael, Cheung, Warren A., Mohammadnia, Abdulshakour, Bechet, Denise, Faury, Damien, McConechy, Melissa K, Pathania, Manav, Jain, Siddhant U., Ellezam, Benjamin, Weil, Alexander G., Montpetit, Alexandre, Salomoni, Paolo, Pastinen, Tomi, Lu, Chao, Lewis, Peter W., Garcia, Benjamin A., Kleinman, Claudia L., Jabado, Nada, Majewski, Jacek
Publicado 2019