The Opioid Epidemic: a Crisis Disproportionately Impacting Black Americans and Urban Communities

por Gondré-Lewis, Marjorie C., Abijo, Tomilowo, Gondré-Lewis, Timothy A.
Publicado 2022

Chemical perturbation of an intrinsically disordered region of TFIID distinguishes two modes of transcription initiation

por Zhang, Zhengjian, Boskovic, Zarko, Hussain, Mahmud M, Hu, Wenxin, Inouye, Carla, Kim, Han-Je, Abole, A Katherine, Doud, Mary K, Lewis, Timothy A, Koehler, Angela N, Schreiber, Stuart L, Tjian, Robert
Publicado 2015

A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G(2)/M DNA Damage Checkpoint

por van Vugt, Marcel A. T. M., Gardino, Alexandra K., Linding, Rune, Ostheimer, Gerard J., Reinhardt, H. Christian, Ong, Shao-En, Tan, Chris S., Miao, Hua, Keezer, Susan M., Li, Jeijin, Pawson, Tony, Lewis, Timothy A., Carr, Steven A., Smerdon, Stephen J., Brummelkamp, Thijn R., Yaffe, Michael B.
Publicado 2010

Macrocyclic Hedgehog Pathway Inhibitors: Optimization of Cellular Activity and Mode of Action Studies

por Dockendorff, Chris, Nagiec, Marek M., Weïwer, Michel, Buhrlage, Sara, Ting, Amal, Nag, Partha P., Germain, Andrew, Kim, Han-Je, Youngsaye, Willmen, Scherer, Christina, Bennion, Melissa, Xue, Linlong, Stanton, Benjamin Z., Lewis, Timothy A., MacPherson, Lawrence, Palmer, Michelle, Foley, Michael A., Perez, José R., Schreiber, Stuart L.
Publicado 2012

Indolinyl-Thiazole Based Inhibitors of Scavenger Receptor-BI (SR-BI)-Mediated Lipid Transport

por Dockendorff, Chris, Faloon, Patrick W., Yu, Miao, Youngsaye, Willmen, Penman, Marsha, Nieland, Thomas J. F., Nag, Partha P., Lewis, Timothy A., Pu, Jun, Bennion, Melissa, Negri, Joseph, Paterson, Conor, Lam, Garrett, Dandapani, Sivaraman, Perez, José R., Munoz, Benito, Palmer, Michelle A., Schreiber, Stuart L., Krieger, Monty
Publicado 2015

Identification of cancer cytotoxic modulators of PDE3A by predictive chemogenomics

por de Waal, Luc, Lewis, Timothy A., Rees, Matthew G., Tsherniak, Aviad, Wu, Xiaoyun, Choi, Peter S., Gechijian, Lara, Hartigan, Christina, Faloon, Patrick W., Hickey, Mark J., Tolliday, Nicola, Carr, Steven A., Clemons, Paul A., Munoz, Benito, Wagner, Bridget K., Shamji, Alykhan F., Koehler, Angela N., Schenone, Monica, Burgin, Alex B., Schreiber, Stuart L., Greulich, Heidi, Meyerson, Matthew
Publicado 2015

Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase

por Garvie, Colin W., Wu, Xiaoyun, Papanastasiou, Malvina, Lee, Sooncheol, Fuller, James, Schnitzler, Gavin R., Horner, Steven W., Baker, Andrew, Zhang, Terry, Mullahoo, James P., Westlake, Lindsay, Hoyt, Stephanie H., Toetzl, Marcus, Ranaghan, Matthew J., de Waal, Luc, McGaunn, Joseph, Kaplan, Bethany, Piccioni, Federica, Yang, Xiaoping, Lange, Martin, Tersteegen, Adrian, Raymond, Donald, Lewis, Timothy A., Carr, Steven A., Cherniack, Andrew D., Lemke, Christopher T., Meyerson, Matthew, Greulich, Heidi
Publicado 2021