Trastuzumab does not bind rat or mouse ErbB2/neu: implications for selection of non-clinical safety models for trastuzumab-based therapeutics

por Lewis Phillips, Gail, Guo, Jun, Kiefer, James R., Proctor, William, Bumbaca Yadav, Daniela, Dybdal, Noel, Shen, Ben-Quan
Publicado 2021

Trastuzumab uptake and its relation to efficacy in an animal model of HER2-positive breast cancer brain metastasis

por Lewis Phillips, Gail D., Nishimura, Merry C., Lacap, Jennifer Arca, Kharbanda, Samir, Mai, Elaine, Tien, Janet, Malesky, Kimberly, Williams, Simon P., Marik, Jan, Phillips, Heidi S.
Publicado 2017

RTK-Dependent Inducible Degradation of Mutant PI3Kα Drives GDC-0077 (Inavolisib) Efficacy

por Song, Kyung W., Edgar, Kyle A., Hanan, Emily J., Hafner, Marc, Oeh, Jason, Merchant, Mark, Sampath, Deepak, Nannini, Michelle A., Hong, Rebecca, Phu, Lilian, Forrest, William F., Stawiski, Eric, Schmidt, Stephen, Endres, Nicholas, Guan, Jane, Wallin, Jeffrey J., Cheong, Jonathan, Plise, Emile G., Lewis Phillips, Gail D., Salphati, Laurent, Heffron, Timothy P., Olivero, Alan G., Malek, Shiva, Staben, Steven T., Kirkpatrick, Donald S., Dey, Anwesha, Friedman, Lori S.
Publicado 2022