RNF11, a new piece in the A20 puzzle

por Jacque, Emilie, Ley, Steven C
Publicado 2009

TNF activation of NF-κB is essential for development of single-positive thymocytes

por Webb, Louise V., Ley, Steven C., Seddon, Benedict
Publicado 2016

Aggregation of Lipid Rafts Accompanies Signaling via the T Cell Antigen Receptor

por Janes, Peter W., Ley, Steven C., Magee, Anthony I.
Publicado 1999

ZAP-70 Protein Tyrosine Kinase Is Constitutively Targeted to the T Cell Cortex Independently of its SH2 Domains

por Huby, Russell D.J., Iwashima, Makio, Weiss, Arthur, Ley, Steven C.
Publicado 1997

BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival

por Jacque, Emilie, Schweighoffer, Edina, Tybulewicz, Victor L.J., Ley, Steven C.
Publicado 2015

Ebola virus VP35 induces high-level production of recombinant TPL-2–ABIN-2–NF-κB1 p105 complex in co-transfected HEK-293 cells

por Gantke, Thorsten, Boussouf, Sabrina, Janzen, Julia, Morrice, Nicholas A., Howell, Steven, Mühlberger, Elke, Ley, Steven C.
Publicado 2013

A20-binding inhibitor of NF-κB (ABIN) 2 negatively regulates allergic airway inflammation

por Ventura, Sonia, Cano, Florencia, Kannan, Yashaswini, Breyer, Felix, Pattison, Michael J., Wilson, Mark S., Ley, Steven C.
Publicado 2018

CARD14(E138A) signalling in keratinocytes induces TNF-dependent skin and systemic inflammation

por Manils, Joan, Webb, Louise V, Howes, Ashleigh, Janzen, Julia, Boeing, Stefan, Bowcock, Anne M, Ley, Steven C
Publicado 2020

TPL-2 restricts Ccl24-dependent immunity to Heligmosomoides polygyrus

por Kannan, Yashaswini, Entwistle, Lewis J., Pelly, Victoria S., Perez-Lloret, Jimena, Walker, Alan W., Ley, Steven C., Wilson, Mark S.
Publicado 2017

TPL-2 Inhibits IFN-β Expression via an ERK1/2-TCF-FOS Axis in TLR4-Stimulated Macrophages

por Blair, Louise, Pattison, Michael J., Chakravarty, Probir, Papoutsopoulou, Stamatia, Bakiri, Latifa, Wagner, Erwin F., Smale, Stephen, Ley, Steven C.
Publicado 2022

IKK-induced NF-κB1 p105 proteolysis is critical for B cell antibody responses to T cell–dependent antigen

por Jacque, Emilie, Schweighoffer, Edina, Visekruna, Alexander, Papoutsopoulou, Stamatia, Janzen, Julia, Zillwood, Rachel, Tarlinton, David M., Tybulewicz, Victor L.J., Ley, Steven C.
Publicado 2014

TLR and TNF-R1 activation of the MKK3/MKK6–p38α axis in macrophages is mediated by TPL-2 kinase

por Pattison, Michael J., Mitchell, Olivia, Flynn, Helen R., Chen, Chao-Sheng, Yang, Huei-Ting, Ben-Addi, Hakem, Boeing, Stefan, Snijders, Ambrosius P., Ley, Steven C.
Publicado 2016

TPL‐2 kinase induces phagosome acidification to promote macrophage killing of bacteria

por Breyer, Felix, Härtlova, Anetta, Thurston, Teresa, Flynn, Helen R, Chakravarty, Probir, Janzen, Julia, Peltier, Julien, Heunis, Tiaan, Snijders, Ambrosius P, Trost, Matthias, Ley, Steven C
Publicado 2021

TPL-2 negatively regulates interferon-β production in macrophages and myeloid dendritic cells

por Kaiser, Frank, Cook, Dorthe, Papoutsopoulou, Stamatia, Rajsbaum, Ricardo, Wu, Xuemei, Yang, Huei-Ting, Grant, Susan, Ricciardi-Castagnoli, Paola, Tsichlis, Philip N., Ley, Steven C., O'Garra, Anne
Publicado 2009

Tumor progression locus 2 reduces severe allergic airway inflammation by inhibiting Ccl24 production in dendritic cells

por Kannan, Yashaswini, Li, Yanda, Coomes, Stephanie M., Okoye, Isobel S., Pelly, Victoria S., Sriskantharajah, Srividya, Gückel, Eva, Webb, Lauren, Czieso, Stephanie, Nikolov, Nikolay, MacDonald, Andrew S., Ley, Steven C., Wilson, Mark S.
Publicado 2017

Assaying kinase activity of the TPL-2/NF-κB1 p105/ABIN-2 complex using an optimal peptide substrate

por Kümper, Sandra, Gantke, Thorsten, Chen, Chao-Sheng, Soneji, Yasmina, Pattison, Michael J., Chakravarty, Probir, Kjær, Svend, Thomas, Daniel, Haslam, Carl, Leavens, Bill J., House, David, Powell, David J., Ley, Steven C.
Publicado 2018

p38γ and p38δ modulate innate immune response by regulating MEF2D activation

por Escós, Alejandra, Diaz-Mora, Ester, Pattison, Michael, Fajardo, Pilar, González-Romero, Diego, Risco, Ana, Martín-Gómez, José, Bonneil, Éric, Sonenberg, Nahum, Jafarnejad, Seyed Mehdi, Sanz-Ezquerro, Juan José, Ley, Steven C, Cuenda, Ana
Publicado 2023

TPL-2 Regulates Macrophage Lipid Metabolism and M2 Differentiation to Control T(H)2-Mediated Immunopathology

por Kannan, Yashaswini, Perez-Lloret, Jimena, Li, Yanda, Entwistle, Lewis J., Khoury, Hania, Papoutsopoulou, Stamatia, Mahmood, Radma, Mansour, Nuha R., Ching-Cheng Huang, Stanley, Pearce, Edward J., Pedro S. de Carvalho, Luiz, Ley, Steven C., Wilson, Mark S.
Publicado 2016