ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment

por Xiang, Jiawen, Pompetti, Anthony J., Faranda, Adam P., Wang, Yan, Novo, Samuel G., Li, David Wan-Cheng, Duncan, Melinda K.
Publicado 2023

Differential expression of the catalytic subunits for PP-1 and PP-2A and the regulatory subunits for PP–2A in mouse eye

por Liu, Wen-Bin, Li, Yong, Zhang, Lan, Chen, He-Ge, Sun, Shuming, Liu, Jin-Ping, Liu, Yun, Li, David Wan-Cheng
Publicado 2008

Multinucleated Retinal Pigment Epithelial Cells Adapt to Vision and Exhibit Increased DNA Damage Response

por Ke, Qin, Gong, Lili, Zhu, Xingfei, Qi, Ruili, Zou, Ming, Chen, Baoxin, Liu, Wei, Huang, Shan, Liu, Yizhi, Li, David Wan-Cheng
Publicado 2022

MAB21L1 promotes survival of lens epithelial cells through control of αB-crystallin and ATR/CHK1/p53 pathway

por Xiao, Yuan, Xiang, Jia-Wen, Gao, Qian, Bai, Yue-Yue, Huang, Zhao-Xia, Hu, Xiao-Hui, Wang, Ling, Li, David Wan-Cheng
Publicado 2022

SUMO1-regulated DBC1 promotes p53-dependent stress-induced apoptosis of lens epithelial cells

por Wang, Yan, Wang, Jing-Miao, Xiao, Yuan, Hu, Xue-Bin, Zheng, Shu-Yu, Fu, Jia-Ling, Zhang, Lan, Gan, Yu-Wen, Liang, Xing-Miao, Li, David Wan-Cheng
Publicado 2023

Transcriptional Regulation of PP2A-Aα Is Mediated by Multiple Factors Including AP-2α, CREB, ETS-1, and SP-1

por Chen, He-Ge, Han, Wen-Jun, Deng, Mi, Qin, Jichao, Yuan, Dan, Liu, Jin-Ping, Xiao, Ling, Gong, Lili, Liang, Songping, Zhang, Jian, Liu, Yun, Li, David Wan-Cheng
Publicado 2009

Inhibition of cGAS-STING by JQ1 alleviates oxidative stress-induced retina inflammation and degeneration

por Zou, Ming, Ke, Qin, Nie, Qian, Qi, Ruili, Zhu, Xingfei, Liu, Wei, Hu, Xuebin, Sun, Qian, Fu, Jia-Ling, Tang, Xiangcheng, Liu, Yizhi, Li, David Wan-Cheng, Gong, Lili
Publicado 2022

The BET PROTAC inhibitor dBET6 protects against retinal degeneration and inhibits the cGAS-STING in response to light damage

por Zhu, Xingfei, Liu, Wei, Tang, Xiangcheng, Chen, Yulin, Ge, Xiangyu, Ke, Qin, Liang, Xingmiao, Gan, Yuwen, Zheng, Yingfeng, Zou, Ming, Deng, Mi, Liu, Yizhi, Li, David Wan-Cheng, Gong, Lili
Publicado 2023

The transcription factor CREB acts as an important regulator mediating oxidative stress-induced apoptosis by suppressing αB-crystallin expression

por Wang, Ling, Nie, Qian, Gao, Meng, Yang, Lan, Xiang, Jia-Wen, Xiao, Yuan, Liu, Fang-Yuan, Gong, Xiao-Dong, Fu, Jia-Ling, Wang, Yan, Nguyen, Quan Dong, Liu, Yizhi, Liu, Mugen, Li, David Wan-Cheng
Publicado 2020

HSF4 regulates lens fiber cell differentiation by activating p53 and its downstream regulators

por Gao, Meng, Huang, Yuwen, Wang, Ling, Huang, Mi, Liu, Fei, Liao, Shengjie, Yu, Shanshan, Lu, Zhaojing, Han, Shanshan, Hu, Xuebin, Qu, Zhen, Liu, Xiliang, Assefa Yimer, Tinsae, Yang, Lifang, Tang, Zhaohui, Li, David Wan-Cheng, Liu, Mugen
Publicado 2017

Aging-dependent loss of GAP junction proteins Cx46 and Cx50 in the fiber cells of human and mouse lenses accounts for the diminished coupling conductance

por Gong, Xiao-Dong, Wang, Yan, Hu, Xue-Bin, Zheng, Shu-Yu, Fu, Jia-Ling, Nie, Qian, Wang, Ling, Hou, Min, Xiang, Jia-Wen, Xiao, Yuan, Gao, Qian, Bai, Yue-Yue, Liu, Yi-Zhi, Li, David Wan-Cheng
Publicado 2021

HSP90β prevents aging-related cataract formation through regulation of the charged multivesicular body protein (CHMP4B) and p53

por Fu, Jia-Ling, Zheng, Shu-Yu, Wang, Yan, Hu, Xue-Bin, Xiao, Yuan, Wang, Jing-Miao, Zhang, Lan, Wang, Ling, Nie, Qian, Hou, Min, Bai, Yue-Yue, Gan, Yu-Wen, Liang, Xing-Miao, Xie, Liu-Liu, Li, David Wan-Cheng
Publicado 2023

PP‐1β and PP‐2Aα modulate cAMP response element‐binding protein (CREB) functions in aging control and stress response through de‐regulation of αB‐crystallin gene and p300‐p53 signa...

por Wang, Ling, Zhang, Lan, Gong, Xiao‐Dong, Fu, Jia‐Ling, Gan, Yu‐Wen, Hou, Min, Nie, Qian, Xiang, Jia‐Wen, Xiao, Yuan, Wang, Yan, Zheng, Shu‐Yu, Yang, Lan, Chen, Huimin, Xiang, Meng‐Qing, Liu, Yizhi, Li, David Wan‐Cheng
Publicado 2021

The Goldfish SG2NA Gene Encodes Two α-Type Regulatory Subunits for PP-2A and Displays Distinct Developmental Expression Pattern

por Ma, Hai-Li, Peng, Yun-Lei, Gong, Lili, Liu, Wen-Bin, Sun, Shuming, Liu, Jiao, Zheng, Chun-Bing, Fu, Hu, Yuan, Dan, Zhao, Junqiong, Chen, Pei-Chao, Xie, Si-si, Zeng, Xiao-Ming, Xiao, Ya-Mei, Liu, Yun, Li, David Wan-Cheng
Publicado 2009

Heterochromatin protects retinal pigment epithelium cells from oxidative damage by silencing p53 target genes

por Gong, Lili, Liu, Fangyuan, Xiong, Zhen, Qi, Ruili, Luo, Zhongwen, Gong, Xiaodong, Nie, Qian, Sun, Qian, Liu, Yun-Fei, Qing, Wenjie, Wang, Ling, Zhang, Lan, Tang, Xiangcheng, Huang, Shan, Li, Gen, Ouyang, Hong, Xiang, Mengqing, Nguyen, Quan Dong, Liu, Yizhi, Li, David Wan-Cheng
Publicado 2018

Molecular signature for senile and complicated cataracts derived from analysis of sumoylation enzymes and their substrates in human cataract lenses

por Liu, Fang‐Yuan, Fu, Jia‐Ling, Wang, Ling, Nie, Qian, Luo, Zhongwen, Hou, Min, Yang, Yuan, Gong, Xiao‐Dong, Wang, Yan, Xiao, Yuan, Xiang, Jiawen, Hu, Xuebin, Zhang, Lan, Wu, Mingxing, Chen, Weirong, Cheng, Bing, Luo, Lixia, Zhang, Xinyu, Liu, Xialin, Zheng, Danying, Huang, Shengsong, Liu, Yizhi, Li, David Wan‐Cheng
Publicado 2020

Molecular Cloning of the Genes Encoding the PR55/Bβ/δ Regulatory Subunits for PP-2A and Analysis of Their Functions in Regulating Development of Goldfish, Carassius auratus

por Zhao, Jun-Qiong, Xie, Si-Si, Liu, Wen-Bin, Xiao, Ya-Mei, Zeng, Xiao-Ming, Deng, Mi, Gong, Lili, Liu, Jin-Ping, Chen, Pei-Chao, Zhou, Jie, Hu, Xiao-Hui, Lv, Jia-Han, Yu, Xiang-Qian, Wang, Dao, Li, Chi, Peng, Yun-Lei, Liao, Gao-Peng, Liu, Yun, Li, David Wan-Cheng
Publicado 2010

The E3 Ligase PIAS1 Regulates p53 Sumoylation to Control Stress-Induced Apoptosis of Lens Epithelial Cells Through the Proapoptotic Regulator Bax

por Nie, Qian, Chen, Huimin, Zou, Ming, Wang, Ling, Hou, Min, Xiang, Jia-Wen, Luo, Zhongwen, Gong, Xiao-Dong, Fu, Jia-Ling, Wang, Yan, Zheng, Shu-Yu, Xiao, Yuan, Gan, Yu-Wen, Gao, Qian, Bai, Yue-Yue, Wang, Jing-Miao, Zhang, Lan, Tang, Xiang-Cheng, Hu, Xuebin, Gong, Lili, Liu, Yizhi, Li, David Wan-Cheng
Publicado 2021

The small heat shock protein αA-crystallin negatively regulates pancreatic tumorigenesis

por Liu, Jifang, Luo, Zhongwen, Zhang, Lan, Wang, Ling, Nie, Qian, Wang, Zheng-Feng, Huang, Zhaoxia, Hu, Xiaohui, Gong, Lili, Arrigo, Andre-Patrick, Tang, Xiangcheng, Xiang, Jia-Wen, Liu, Fangyuan, Deng, Mi, Ji, Weike, Hu, Wenfeng, Zhu, Ji-Ye, Chen, Baojiang, Bridge, Julia, Hollingsworth, Michael A., Gigantelli, James, Liu, Yizhi, Nguyen, Quan D., Li, David Wan-Cheng
Publicado 2016

MYPT1/PP1‐Mediated EZH2 Dephosphorylation at S21 Promotes Epithelial–Mesenchymal Transition in Fibrosis through Control of Multiple Families of Genes

por Zhang, Lan, Wang, Ling, Hu, Xue‐Bin, Hou, Min, Xiao, Yuan, Xiang, Jia‐Wen, Xie, Jie, Chen, Zhi‐Gang, Yang, Tian‐Heng, Nie, Qian, Fu, Jia‐Ling, Wang, Yan, Zheng, Shu‐Yu, Liu, Yun‐Fei, Gan, Yu‐Wen, Gao, Qian, Bai, Yue‐Yue, Wang, Jing‐Miao, Qi, Rui‐Li, Zou, Ming, Ke, Qin, Zhu, Xing‐Fei, Gong, Lili, Liu, Yizhi, Li, David Wan‐Cheng
Publicado 2022