The Small Molecule, LLL12, Inhibits STAT3 Phosphorylation and Induces Apoptosis in Medulloblastoma and Glioblastoma Cells

por Ball, Sarah, Li, Chenglong, Li, Pui-Kai, Lin, Jiayuh
Publicado 2011

Therapeutic Effects of a Novel Phenylphthalimide Analog for Corneal Neovascularization and Retinal Vascular Leakage

por Wang, Bing, Li, Pui-Kai, Ma, Jian-xing, Chen, Danyang
Publicado 2018

BET Bromodomain Inhibitors: Novel Design Strategies and Therapeutic Applications

por To, Kenneth K. W., Xing, Enming, Larue, Ross C., Li, Pui-Kai
Publicado 2023

Computational modeling studies reveal the origin of the binding preference of 3‐(3,4‐di hydroisoquinolin‐2(1H)‐ylsulfonyl)benzoic acids for AKR1C3 over its isoforms

por Kong, Xiaotian, Xing, Enming, Wu, Sijin, Zhuang, Tony, Li, Pui‐Kai, Li, Chunhua, Cheng, Xiaolin
Publicado 2022

Constitutively Active Androgen Receptor in Hepatocellular Carcinoma

por Montgomery, Emma J., Xing, Enming, Campbell, Moray J., Li, Pui-Kai, Blachly, James S., Tsung, Allan, Coss, Christopher C.
Publicado 2022

SAT021 Development Of Niclosamide Analogs For Treatment Of Androgen Receptor Positive Hepatocellular Carcinoma

por Jordan Montgomery, Emma, Xing, Enming, Dauki, Anees, Radomska, Hanna, Kiyota Kulp, Samuel, Granchie, Lauren, Li, Pui-Kai, Charles Coss, Christopher
Publicado 2023

STAT3 as a potential therapeutic target in ALDH(+) and CD44(+)/CD24(+) stem cell-like pancreatic cancer cells

por Lin, Li, Jou, David, Wang, Yina, Ma, Haiyan, Liu, Tianshu, Fuchs, James, Li, Pui-Kai, Lü, Jiagao, Li, Chenglong, Lin, Jiayuh
Publicado 2016

New structural analogues of curcumin exhibit potent growth suppressive activity in human colorectal carcinoma cells

por Cen, Ling, Hutzen, Brian, Ball, Sarah, DeAngelis, Stephanie, Chen, Chun-Liang, Fuchs, James R, Li, Chenglong, Li, Pui-Kai, Lin, Jiayuh
Publicado 2009

Characterization of STAT3 activation and expression in canine and human osteosarcoma

por Fossey, Stacey L, Liao, Albert T, McCleese, Jennifer K, Bear, Misty D, Lin, Jiayuh, Li, Pui-Kai, Kisseberth, William C, London, Cheryl A
Publicado 2009

A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells

por Lin, Li, Deangelis, Stephanie, Foust, Elizabeth, Fuchs, James, Li, Chenglong, Li, Pui-Kai, Schwartz, Eric B, Lesinski, Gregory B, Benson, Don, Lü, Jiagao, Hoyt, Dale, Lin, Jiayuh
Publicado 2010

The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines

por Fossey, Stacey L, Bear, Misty D, Lin, Jiayuh, Li, Chenglong, Schwartz, Eric B, Li, Pui-Kai, Fuchs, James R, Fenger, Joelle, Kisseberth, William C, London, Cheryl A
Publicado 2011

Evaluation of STAT3 Signaling in ALDH+ and ALDH+/CD44+/CD24− Subpopulations of Breast Cancer Cells

por Lin, Li, Hutzen, Brian, Lee, Hsiu-Fang, Peng, Zhengang, Wang, Wenlong, Zhao, Chongqiang, Lin, Huey-Jen, Sun, Duxin, Li, Pui-Kai, Li, Chenglong, Korkaya, Hasan, Wicha, Max S., Lin, Jiayuh
Publicado 2013

Phosphoproteomic analysis of anaplastic lymphoma kinase (ALK) downstream signaling pathways identifies signal transducer and activator of transcription 3 as a functional target of...

por Sattu, Kamaraj, Hochgräfe, Falko, Wu, Jianmin, Umapathy, Ganesh, Schönherr, Christina, Ruuth, Kristina, Chand, Damini, Witek, Barbara, Fuchs, James, Li, Pui-Kai, Hugosson, Fredrik, Daly, Roger J, Palmer, Ruth H, Hallberg, Bengt
Publicado 2013

ARVib suppresses growth of advanced prostate cancer via inhibition of androgen receptor signaling

por Liu, Chengfei, Armstrong, Cameron M., Ning, Shu, Yang, Joy C., Lou, Wei, Lombard, Alan P., Zhao, Jinge, Wu, Chun-Yi, Yu, Aiming, Evans, Christopher P., Tepper, Clifford G., Li, Pui-kai, Gao, Allen C.
Publicado 2021

Structurally Modified Curcumin Analogs Inhibit STAT3 Phosphorylation and Promote Apoptosis of Human Renal Cell Carcinoma and Melanoma Cell Lines

por Bill, Matthew A., Nicholas, Courtney, Mace, Thomas A., Etter, Jonathan P., Li, Chenglong, Schwartz, Eric B., Fuchs, James R., Young, Gregory S., Lin, Li, Lin, Jiayuh, He, Lei, Phelps, Mitch, Li, Pui-Kai, Lesinski, Gregory B.
Publicado 2012

The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity

por Bill, Matthew A, Fuchs, James R, Li, Chenglong, Yui, Jennifer, Bakan, Courtney, Benson, Don M, Schwartz, Eric B, Abdelhamid, Dalia, Lin, Jiayuh, Hoyt, Dale G, Fossey, Stacey L, Young, Gregory S, Carson, William E, Li, Pui-Kai, Lesinski, Gregory B
Publicado 2010

Niclosamide and its analogs are potent inhibitors of Wnt/β-catenin, mTOR and STAT3 signaling in ovarian cancer

por Arend, Rebecca C., Londoño-Joshi, Angelina I., Gangrade, Abhishek, Katre, Ashwini A., Kurpad, Chandrika, Li, Yonghe, Samant, Rajeev S., Li, Pui-Kai, Landen, Charles N., Yang, Eddy S., Hidalgo, Bertha, Alvarez, Ronald D., Michael Straughn, John, Forero, Andres, Buchsbaum, Donald J.
Publicado 2016

Correction: Niclosamide and its analogs are potent inhibitors of Wnt/β-catenin, mTOR and STAT3 signaling in ovarian cancer

por Arend, Rebecca C., Londoño-Joshi, Angelina I., Gangrade, Abhishek, Katre, Ashwini A., Kurpad, Chandrika, Li, Yonghe, Samant, Rajeev S., Li, Pui-Kai, Landen, Charles N., Yang, Eddy S., Hidalgo, Bertha, Alvarez, Ronald D., Straughn, John Michael, Forero, Andres, Buchsbaum, Donald J.
Publicado 2018