Artesunate: The Best Drug in the Treatment of Severe and Complicated Malaria

por Li, Qigui, Weina, Peter
Publicado 2010

Severe Embryotoxicity of Artemisinin Derivatives in Experimental Animals, but Possibly Safe in Pregnant Women

por Li, Qigui, Weina, Peter J.
Publicado 2009

Bioequivalence of Two Intravenous Artesunate Products with Its Active Metabolite Following Single and Multiple Injections

por Li, Qigui, Xie, Lisa, Melendez, Victor, Weina, Peter
Publicado 2011

Pharmacokinetics, tissue distribution and mass balance of radiolabeled dihydroartemisinin in male rats

por Xie, Lisa H, Li, Qigui, Zhang, Jing, Weina, Peter J
Publicado 2009

Efficacy of intravenous methylene blue, intravenous artesunate, and their combination in preclinical models of malaria

por Ohrt, Colin, Li, Qigui, Obaldia, Nicanor, Im-erbsin, Rawiwan, Xie, Lisa, Berman, Jonathan
Publicado 2014

Formulation and Particle Size Reduction Improve Bioavailability of Poorly Water-Soluble Compounds with Antimalarial Activity

por Wang, Hongxing, Li, Qigui, Reyes, Sean, Zhang, Jing, Xie, Lisa, Melendez, Victor, Hickman, Mark, Kozar, Michael P.
Publicado 2013

Assessment of the prophylactic activity and pharmacokinetic profile of oral tafenoquine compared to primaquine for inhibition of liver stage malaria infections

por Li, Qigui, O’Neil, Michael, Xie, Lisa, Caridha, Diana, Zeng, Qiang, Zhang, Jing, Pybus, Brandon, Hickman, Mark, Melendez, Victor
Publicado 2014

Anti-relapse activity of mirincamycin in the Plasmodium cynomolgi sporozoite-infected Rhesus monkey model

por Fracisco, Susan, Teja-isavadharm, Paktiya, Gettayacamin, Montip, Berman, Jonathan, Li, Qigui, Melendez, Victor, Saunders, David, Xie, Lisa, Ohrt, Colin
Publicado 2014

Pharmacokinetic profiles of artesunate following multiple intravenous doses of 2, 4, and 8 mg/kg in healthy volunteers: Phase 1b study

por Miller, Robert Scott, Li, Qigui, Cantilena, Louis R, Leary, Kevin J, Saviolakis, George A, Melendez, Victor, Smith, Bryan, Weina, Peter J
Publicado 2012

Pharmacokinetic evaluation of intravenous artesunate in adults with uncomplicated falciparum malaria in Kenya: a phase II study

por Li, Qigui, Remich, Shon, Miller, Scott R, Ogutu, Bernhards, Otieno, Walter, Melendez, Victor, Teja-Isavadharm, Paktiya, Weina, Peter J, Hickman, Mark R, Smith, Bryan, Polhemus, Mark
Publicado 2014

Long-Term Prophylaxis and Pharmacokinetic Evaluation of Intramuscular Nano- and Microparticle Decoquinate in Mice Infected with P. berghei Sporozoites

por Li, Qigui, Xie, Lisa, Caridha, Diana, Zeng, Qiang, Zhang, Jing, Roncal, Norma, Zhang, Ping, Vuong, Chau, Potter, Brittney, Sousa, Jason, Marcsisin, Sean, Read, Lisa, Hickman, Mark
Publicado 2017

The metabolism of primaquine to its active metabolite is dependent on CYP 2D6

por Pybus, Brandon S, Marcsisin, Sean R, Jin, Xiannu, Deye, Gregory, Sousa, Jason C, Li, Qigui, Caridha, Diana, Zeng, Qiang, Reichard, Gregory A, Ockenhouse, Christian, Bennett, Jason, Walker, Larry A, Ohrt, Colin, Melendez, Victor
Publicado 2013

Cytochrome P450 2D-mediated metabolism is not necessary for tafenoquine and primaquine to eradicate the erythrocytic stages of Plasmodium berghei

por Milner, Erin E., Berman, Jonathan, Caridha, Diana, Dickson, Samuel P., Hickman, Mark, Lee, Patricia J., Marcsisin, Sean R., Read, Lisa T., Roncal, Norma, Vesely, Brian A., Xie, Lisa H., Zhang, Jing, Zhang, Ping, Li, Qigui
Publicado 2016

Identification and Fine Mapping of the Recessive Gene BK-5, Which Affects Cell Wall Biosynthesis and Plant Brittleness in Maize

por Li, Qigui, Nie, Shujun, Li, Gaoke, Du, Jiyuan, Ren, Ruchang, Yang, Xiu, Liu, Boyan, Gao, Xiaolong, Liu, Tianjian, Zhang, Zhiming, Zhao, Xiangyu, Li, Xinzheng, Nie, Yongxin, Wang, Baichen, Lin, Haijian, Ding, Haiping, Pan, Guangtang
Publicado 2022

Pre-clinical evaluation of CYP 2D6 dependent drug–drug interactions between primaquine and SSRI/SNRI antidepressants

por Jin, Xiannu, Potter, Brittney, Luong, Thu-lan, Nelson, Jennifer, Vuong, Chau, Potter, Corttney, Xie, Lisa, Zhang, Jing, Zhang, Ping, Sousa, Jason, Li, Qigui, Pybus, Brandon S., Kreishman-Deitrick, Mara, Hickman, Mark, Smith, Philip L., Paris, Robert, Reichard, Gregory, Marcsisin, Sean R.
Publicado 2016

Updating the modified Thompson test by using whole-body bioluminescence imaging to replace traditional efficacy testing in experimental models of murine malaria

por Caridha, Diana, Hickman, Mark, Xie, Lisa, Ngundam, Franklyn, Milner, Erin, Schenk, Amanda, Butler, Kirk, Nugent, Dylan, Lee, Patricia, Roncal, Norma, Leed, Susan, Hosford, Eve, Lee, Jangwoo, Sciotti, Richard J., Reichard, Gregory, Black, Chad, Kreishman-Deitrick, Mara, Li, Qigui, Vesely, Brian
Publicado 2019

Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the 8-aminoquinoline class of anti-malarial compounds

por Marcsisin, Sean R, Sousa, Jason C, Reichard, Gregory A, Caridha, Diana, Zeng, Qiang, Roncal, Norma, McNulty, Ronan, Careagabarja, Julio, Sciotti, Richard J, Bennett, Jason W, Zottig, Victor E, Deye, Gregory, Li, Qigui, Read, Lisa, Hickman, Mark, Nanayakkara, N P Dhammika, Walker, Larry A, Smith, Bryan, Melendez, Victor, Pybus, Brandon S
Publicado 2014

Corrigendum to: Determination of Cytochrome P450 Isoenzyme 2D6 (CYP2D6) Genotypes and Pharmacogenomic Impact on Primaquine Metabolism in an Active-Duty US Military Population

por Spring, Michele D, Sousa, Jason C, Li, Qigui, Darko, Christian A, Morrison, Meshell N, Marcsisin, Sean R, Mills, Kristin T, Potter, Brittney M, Paolino, Kristopher M, Twomey, Patrick S, Moon, James E, Tosh, Donna M, Cicatelli, Susan B, Froude, Jeffrey W, Pybus, Brandon S, Oliver, Thomas G, Mccarthy, William F, Waters, Norman C, Smith, Philip L, Reichard, Gregory A, Bennett, Jason W
Publicado 2020

Determination of Cytochrome P450 Isoenzyme 2D6 (CYP2D6) Genotypes and Pharmacogenomic Impact on Primaquine Metabolism in an Active-Duty US Military Population

por Spring, Michele D, Sousa, Jason C, Li, Qigui, Darko, Christian A, Morrison, Meshell N, Marcsisin, Sean R, Mills, Kristin T, Potter, Brittney M, Paolino, Kristopher M, Twomey, Patrick S, Moon, James E, Tosh, Donna M, Cicatelli, Susan B, Froude, Jeffrey W, Pybus, Brandon S, Oliver, Thomas G, McCarthy, William F, Waters, Norman C, Smith, Philip L, Reichard, Gregory A, Bennett, Jason W
Publicado 2019

Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites

por McPhillie, Martin J., Zhou, Ying, Hickman, Mark R., Gordon, James A., Weber, Christopher R., Li, Qigui, Lee, Patty J., Amporndanai, Kangsa, Johnson, Rachel M., Darby, Heather, Woods, Stuart, Li, Zhu-hong, Priestley, Richard S., Ristroph, Kurt D., Biering, Scott B., El Bissati, Kamal, Hwang, Seungmin, Hakim, Farida Esaa, Dovgin, Sarah M., Lykins, Joseph D., Roberts, Lucy, Hargrave, Kerrie, Cong, Hua, Sinai, Anthony P., Muench, Stephen P., Dubey, Jitender P., Prud'homme, Robert K., Lorenzi, Hernan A., Biagini, Giancarlo A., Moreno, Silvia N., Roberts, Craig W., Antonyuk, Svetlana V., Fishwick, Colin W. G., McLeod, Rima
Publicado 2020