Long-term Temporal Stability of Peripheral Blood DNA Methylation Profiles in Patients With Inflammatory Bowel Disease

por Joustra, Vincent, Li Yim, Andrew Y.F., Hageman, Ishtu, Levin, Evgeni, Adams, Alex, Satsangi, Jack, de Jonge, Wouter J., Henneman, Peter, D’Haens, Geert
Publicado 2022

Systematic Review and Meta-analysis of Peripheral Blood DNA Methylation Studies in Inflammatory Bowel Disease

por Joustra, Vincent, Hageman, Ishtu L, Satsangi, Jack, Adams, Alex, Ventham, Nicholas T, de Jonge, Wouter J, Henneman, Peter, D’Haens, Geert R, Li Yim, Andrew Y F
Publicado 2022

Peripheral Blood DNA Methylation Profiles Do Not Predict Endoscopic Post-Operative Recurrence in Crohn’s Disease Patients

por Joustra, Vincent W., Li Yim, Andrew Y. F., de Bruyn, Jessica R., Duijvestein, Marjolijn, Hageman, Ishtu L., de Jonge, Wouter J., Henneman, Peter, Wildenberg, Manon, D’Haens, Geert
Publicado 2022

Meta-Analysis of in vitro-Differentiated Macrophages Identifies Transcriptomic Signatures That Classify Disease Macrophages in vivo

por Chen, Hung-Jen, Li Yim, Andrew Y. F., Griffith, Guillermo R., de Jonge, Wouter J., Mannens, Marcel M. A. M., Ferrero, Enrico, Henneman, Peter, de Winther, Menno P. J.
Publicado 2019

Whole-Genome DNA Methylation Profiling of CD14+ Monocytes Reveals Disease Status and Activity Differences in Crohn’s Disease Patients

por Li Yim, Andrew Y.F., Duijvis, Nicolette W., Ghiboub, Mohammed, Sharp, Catriona, Ferrero, Enrico, Mannens, Marcel M.A.M., D’Haens, Geert R., de Jonge, Wouter J., te Velde, Anje A., Henneman, Peter
Publicado 2020

Peripheral blood methylation profiling of female Crohn’s disease patients

por Li Yim, Andrew Y. F., Duijvis, Nicolette W., Zhao, Jing, de Jonge, Wouter J., D’Haens, Geert R. A. M., Mannens, Marcel M. A. M., Mul, Adri N. P. M., te Velde, Anje A., Henneman, Peter
Publicado 2016

The role of nicotinic receptors in SARS-CoV-2 receptor ACE2 expression in intestinal epithelia

por ten Hove, Anne S., Brinkman, David J., Li Yim, Andrew Y. F., Verseijden, Caroline, Hakvoort, Theo B. M., Admiraal, Iris, Welting, Olaf, van Hamersveld, Patricia H. P., Sinniger, Valérie, Bonaz, Bruno, Luyer, Misha D., de Jonge, Wouter J.
Publicado 2020

A distinct epigenetic profile distinguishes stenotic from non-inflamed fibroblasts in the ileal mucosa of Crohn’s disease patients

por Li Yim, Andrew Y. F., de Bruyn, Jessica R., Duijvis, Nicolette W., Sharp, Catriona, Ferrero, Enrico, de Jonge, Wouter J., Wildenberg, Manon E., Mannens, Marcel M. A. M., Buskens, Christianne J., D’Haens, Geert R., Henneman, Peter, te Velde, Anje A.
Publicado 2018

Epigenetic Signatures Discriminate Patients With Primary Sclerosing Cholangitis and Ulcerative Colitis From Patients With Ulcerative Colitis

por de Krijger, Manon, Hageman, Ishtu L., Li Yim, Andrew Y. F., Verhoeff, Jan, Garcia Vallejo, Juan J., van Hamersveld, Patricia H. P., Levin, Evgeni, Hakvoort, Theodorus B. M., Wildenberg, Manon E., Henneman, Peter, Ponsioen, Cyriel Y., de Jonge, Wouter J.
Publicado 2022

HDAC3 Mediates the Inflammatory Response and LPS Tolerance in Human Monocytes and Macrophages

por Ghiboub, Mohammed, Zhao, Jing, Li Yim, Andrew Y. F., Schilderink, Ronald, Verseijden, Caroline, van Hamersveld, Patricia H. P., Duarte, Jose M., Hakvoort, Theodorus B. M., Admiraal, Iris, Harker, Nicola R., Tough, David F., Henneman, Peter, de Winther, Menno P. J., de Jonge, Wouter J.
Publicado 2020

Novel Insights Into Rheumatoid Arthritis Through Characterization of Concordant Changes in DNA Methylation and Gene Expression in Synovial Biopsies of Patients With Differing Numbe...

por Li Yim, Andrew Y. F., Ferrero, Enrico, Maratou, Klio, Lewis, Huw D., Royal, George, Tough, David F., Larminie, Chris, Mannens, Marcel M. A. M., Henneman, Peter, de Jonge, Wouter J., van de Sande, Marleen G. H., Gerlag, Danielle M., Prinjha, Rab K., Tak, Paul P.
Publicado 2021

Effects of fecal microbiota transplant on DNA methylation in subjects with metabolic syndrome

por van der Vossen, Eduard W. J., Bastos, Diogo, Stols-Gonçalves, Daniela, de Goffau, Marcus C., Davids, Mark, Pereira, Joao P. B., Li Yim, Andrew Y. F., Henneman, Peter, Netea, Mihai G., de Vos, Willem M., de Jonge, Wouter, Groen, Albert K., Nieuwdorp, Max, Levin, Evgeni
Publicado 2021

Histology and transcriptome insights into the early processes of intestinal anastomotic healing: a rat model

por van Helsdingen, Claire P M, Wildeboer, Aurelia C L, Zafeiropoulou, Konstantina, Jongen, Audrey C H M, Bosmans, Joanna W A M, Gallé, Camille, Hakvoort, Theodorus B M, Gijbels, Marion J J, de Jonge, Wouter J, Bouvy, Nicole D, Li Yim, Andrew Y F, Derikx, Joep P M
Publicado 2023

A BET Protein Inhibitor Targeting Mononuclear Myeloid Cells Affects Specific Inflammatory Mediators and Pathways in Crohn’s Disease

por Elfiky, Ahmed M. I., Hageman, Ishtu L., Becker, Marte A. J., Verhoeff, Jan, Li Yim, Andrew Y. F., Joustra, Vincent W., Mulders, Lieven, Fung, Ivan, Rioja, Inmaculada, Prinjha, Rab K., Smithers, Nicholas N., Furze, Rebecca C., Mander, Palwinder K., Bell, Matthew J., Buskens, Christianne J., D’Haens, Geert R., Wildenberg, Manon E., de Jonge, Wouter J.
Publicado 2022

Carboxylesterase-1 Assisted Targeting of HDAC Inhibitors to Mononuclear Myeloid Cells in Inflammatory Bowel Disease

por Elfiky, Ahmed M I, Ghiboub, Mohammed, Li Yim, Andrew Y F, Hageman, Ishtu L, Verhoeff, Jan, de Krijger, Manon, van Hamersveld, Patricia H P, Welting, Olaf, Admiraal, Iris, Rahman, Shafaque, Garcia-Vallejo, Juan J, Wildenberg, Manon E, Tomlinson, Laura, Gregory, Richard, Rioja, Inmaculada, Prinjha, Rab K, Furze, Rebecca C, Lewis, Huw D, Mander, Palwinder K, Heinsbroek, Sigrid E M, Bell, Matthew J, de Jonge, Wouter J
Publicado 2021

Modulation of macrophage inflammatory function through selective inhibition of the epigenetic reader protein SP140

por Ghiboub, Mohammed, Koster, Jan, Craggs, Peter D., Li Yim, Andrew Y. F., Shillings, Anthony, Hutchinson, Sue, Bingham, Ryan P., Gatfield, Kelly, Hageman, Ishtu L., Yao, Gang, O’Keefe, Heather P., Coffin, Aaron, Patel, Amish, Sloan, Lisa A., Mitchell, Darren J., Hayhow, Thomas G., Lunven, Laurent, Watson, Robert J., Blunt, Christopher E., Harrison, Lee A., Bruton, Gordon, Kumar, Umesh, Hamer, Natalie, Spaull, John R., Zwijnenburg, Danny A., Welting, Olaf, Hakvoort, Theodorus B. M., te Velde, Anje A., van Limbergen, Johan, Henneman, Peter, Prinjha, Rab K., de Winther, Menno P. J., Harker, Nicola R., Tough, David F., de Jonge, Wouter J.
Publicado 2022