Mapping and modeling the genomic basis of differential RNA isoform expression at single-cell resolution with LR-Split-seq

por Rebboah, Elisabeth, Reese, Fairlie, Williams, Katherine, Balderrama-Gutierrez, Gabriela, McGill, Cassandra, Trout, Diane, Rodriguez, Isaryhia, Liang, Heidi, Wold, Barbara J., Mortazavi, Ali
Publicado 2021

C5aR1 antagonism suppresses inflammatory glial gene expression and alters cellular signaling in an aggressive Alzheimer’s model

por Schartz, Nicole D., Liang, Heidi Y., Carvalho, Klebea, Chu, Shu-Hui, Mendoza-Arvilla, Adrian, Petrisko, Tiffany J., Gomez-Arboledas, Angela, Mortazavi, Ali, Tenner, Andrea J.
Publicado 2023

Modulation of C5a–C5aR1 signaling alters the dynamics of AD progression

por Carvalho, Klebea, Schartz, Nicole D., Balderrama-Gutierrez, Gabriela, Liang, Heidi Y., Chu, Shu-Hui, Selvan, Purnika, Gomez-Arboledas, Angela, Petrisko, Tiffany J., Fonseca, Maria I., Mortazavi, Ali, Tenner, Andrea J.
Publicado 2022

C5aR1 antagonism alters microglial polarization and mitigates disease progression in a mouse model of Alzheimer’s disease

por Gomez-Arboledas, Angela, Carvalho, Klebea, Balderrama-Gutierrez, Gabriela, Chu, Shu-Hui, Liang, Heidi Yahan, Schartz, Nicole D., Selvan, Purnika, Petrisko, Tiffany J., Pan, Miranda A., Mortazavi, Ali, Tenner, Andrea J.
Publicado 2022

A Trem2(R47H) mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques

por Tran, Kristine M., Kawauchi, Shimako, Kramár, Enikö A., Rezaie, Narges, Liang, Heidi Yahan, Sakr, Jasmine S., Gomez-Arboledas, Angela, Arreola, Miguel A., Cunha, Celia da, Phan, Jimmy, Wang, Shuling, Collins, Sherilyn, Walker, Amber, Shi, Kai-Xuan, Neumann, Jonathan, Filimban, Ghassan, Shi, Zechuan, Milinkeviciute, Giedre, Javonillo, Dominic I., Tran, Katelynn, Gantuz, Magdalena, Forner, Stefania, Swarup, Vivek, Tenner, Andrea J., LaFerla, Frank M., Wood, Marcelo A., Mortazavi, Ali, MacGregor, Grant R., Green, Kim N.
Publicado 2023

The ENCODE4 long-read RNA-seq collection reveals distinct classes of transcript structure diversity

por Reese, Fairlie, Williams, Brian, Balderrama-Gutierrez, Gabriela, Wyman, Dana, Çelik, Muhammed Hasan, Rebboah, Elisabeth, Rezaie, Narges, Trout, Diane, Razavi-Mohseni, Milad, Jiang, Yunzhe, Borsari, Beatrice, Morabito, Samuel, Liang, Heidi Yahan, McGill, Cassandra J., Rahmanian, Sorena, Sakr, Jasmine, Jiang, Shan, Zeng, Weihua, Carvalho, Klebea, Weimer, Annika K., Dionne, Louise A., McShane, Ariel, Bedi, Karan, Elhajjajy, Shaimae I., Upchurch, Sean, Jou, Jennifer, Youngworth, Ingrid, Gabdank, Idan, Sud, Paul, Jolanki, Otto, Strattan, J. Seth, Kagda, Meenakshi S., Snyder, Michael P., Hitz, Ben C., Moore, Jill E., Weng, Zhiping, Bennett, David, Reinholdt, Laura, Ljungman, Mats, Beer, Michael A., Gerstein, Mark B., Pachter, Lior, Guigó, Roderic, Wold, Barbara J., Mortazavi, Ali
Publicado 2023

Signalling by senescent melanocytes hyperactivates hair growth

por Wang, Xiaojie, Ramos, Raul, Phan, Anne Q., Yamaga, Kosuke, Flesher, Jessica L., Jiang, Shan, Oh, Ji Won, Jin, Suoqin, Jahid, Sohail, Kuan, Chen-Hsiang, Nguyen, Truman Kt, Liang, Heidi Y., Shettigar, Nitish Udupi, Hou, Renzhi, Tran, Kevin H., Nguyen, Andrew, Vu, Kimberly N., Phung, Jennie L., Ingal, Jonard P., Levitt, Katelyn M., Cao, Xiaoling, Liu, Yingzi, Deng, Zhili, Taguchi, Nobuhiko, Scarfone, Vanessa M., Wang, Guangfang, Paolilli, Kara Nicole, Wang, Xiaoyang, Guerrero-Juarez, Christian F., Davis, Ryan T., Greenberg, Elyse Noelani, Ruiz-Vega, Rolando, Vasudeva, Priya, Murad, Rabi, Widyastuti, Lily Halida Putri, Lee, Hye-Lim, McElwee, Kevin J., Gadeau, Alain-Pierre, Lawson, Devon A., Andersen, Bogi, Mortazavi, Ali, Yu, Zhengquan, Nie, Qing, Kunisada, Takahiro, Karin, Michael, Tuckermann, Jan, Esko, Jeffrey D., Ganesan, Anand K., Li, Ji, Plikus, Maksim V.
Publicado 2023