New Horizons in KRAS-Mutant Lung Cancer: Dawn After Darkness

por Yang, Haitang, Liang, Shun-Qing, Schmid, Ralph A., Peng, Ren-Wang
Publicado 2019

Tissue-restricted genome editing in vivo specified by microRNA-repressible anti-CRISPR proteins

por Lee, Jooyoung, Mou, Haiwei, Ibraheim, Raed, Liang, Shun-Qing, Liu, Pengpeng, Xue, Wen, Sontheimer, Erik J.
Publicado 2019

HSP90/AXL/eIF4E-regulated unfolded protein response as an acquired vulnerability in drug-resistant KRAS-mutant lung cancer

por Yang, Haitang, Liang, Shun-Qing, Xu, Duo, Yang, Zhang, Marti, Thomas M., Gao, Yanyun, Kocher, Gregor J., Zhao, Heng, Schmid, Ralph A., Peng, Ren-Wang
Publicado 2019

Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice

por Liu, Pengpeng, Liang, Shun-Qing, Zheng, Chunwei, Mintzer, Esther, Zhao, Yan G., Ponnienselvan, Karthikeyan, Mir, Aamir, Sontheimer, Erik J., Gao, Guangping, Flotte, Terence R., Wolfe, Scot A., Xue, Wen
Publicado 2021

Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma

por Xu, Duo, Liang, Shun-Qing, Yang, Haitang, Lüthi, Ursina, Riether, Carsten, Berezowska, Sabina, Marti, Thomas M., Hall, Sean R. R., Bruggmann, Rémy, Kocher, Gregor J., Schmid, Ralph A., Peng, Ren-Wang
Publicado 2018

Endoplasmic Reticulum Stress Signaling as a Therapeutic Target in Malignant Pleural Mesothelioma

por Xu, Duo, Yang, Haitang, Yang, Zhang, Berezowska, Sabina, Gao, Yanyun, Liang, Shun-Qing, Marti, Thomas M., Hall, Sean R. R., Dorn, Patrick, Kocher, Gregor J., Schmid, Ralph A., Peng, Ren-Wang
Publicado 2019

Malignant pleural mesothelioma co-opts BCL-X(L) and autophagy to escape apoptosis

por Xu, Duo, Liang, Shun-Qing, Yang, Zhang, Yang, Haitang, Bruggmann, Rémy, Oberhaensli, Simone, Berezowska, Sabina, Marti, Thomas M., Hall, Sean R. R., Dorn, Patrick, Kocher, Gregor J., Schmid, Ralph A., Peng, Ren-Wang
Publicado 2021

Metabolic synthetic lethality by targeting NOP56 and mTOR in KRAS-mutant lung cancer

por Yang, Zhang, Liang, Shun-Qing, Zhao, Liang, Yang, Haitang, Marti, Thomas M., Hegedüs, Balazs, Gao, Yanyun, Zheng, Bin, Chen, Chun, Wang, Wenxiang, Dorn, Patrick, Kocher, Gregor J., Schmid, Ralph A., Peng, Ren-Wang
Publicado 2022

Genome-wide detection of CRISPR editing in vivo using GUIDE-tag

por Liang, Shun-Qing, Liu, Pengpeng, Smith, Jordan L., Mintzer, Esther, Maitland, Stacy, Dong, Xiaolong, Yang, Qiyuan, Lee, Jonathan, Haynes, Cole M., Zhu, Lihua Julie, Watts, Jonathan K., Sontheimer, Erik J., Wolfe, Scot A., Xue, Wen
Publicado 2022

Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS‐mutant cancer

por Yang, Zhang, Liang, Shun‐Qing, Saliakoura, Maria, Yang, Haitang, Vassella, Eric, Konstantinidou, Georgia, Tschan, Mario, Hegedüs, Balazs, Zhao, Liang, Gao, Yanyun, Xu, Duo, Deng, Haibin, Marti, Thomas M, Kocher, Gregor J, Wang, Wenxiang, Schmid, Ralph A, Peng, Ren‐Wang
Publicado 2021

MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma

por Yang, Haitang, Gao, Yanyun, Xu, Duo, Xu, Ke, Liang, Shun-Qing, Yang, Zhang, Scherz, Amina, Hall, Sean R. R., Forster, Stefan, Berezowska, Sabina, Yao, Feng, Ochsenbein, Adrian F., Marti, Thomas M., Kocher, Gregor J., Schmid, Ralph A., Dorn, Patrick, Peng, Ren-Wang
Publicado 2023