Insulator dysfunction and oncogene activation in IDH mutant gliomas

por Flavahan, William A., Drier, Yotam, Liau, Brian B., Gillespie, Shawn M., Venteicher, Andrew S., Stemmer-Rachamimov, Anat O., Suvà, Mario L., Bernstein, Bradley E.
Publicado 2015

Profiling the Landscape of Drug Resistance Mutations in Neosubstrates to Molecular Glue Degraders

por Gosavi, Pallavi M., Ngan, Kevin C., Yeo, Megan J. R., Su, Cindy, Li, Jiaming, Lue, Nicholas Z., Hoenig, Samuel M., Liau, Brian B.
Publicado 2022

Polycomb-lamina antagonism partitions heterochromatin at the nuclear periphery

por Siegenfeld, Allison P., Roseman, Shelby A., Roh, Heejin, Lue, Nicholas Z., Wagen, Corin C., Zhou, Eric, Johnstone, Sarah E., Aryee, Martin J., Liau, Brian B.
Publicado 2022

Activity-based CRISPR scanning uncovers allostery in DNA methylation maintenance machinery

por Ngan, Kevin Chun-Ho, Hoenig, Samuel M, Kwok, Hui Si, Lue, Nicholas Z, Gosavi, Pallavi M, Tanner, David A, Garcia, Emma M, Lee, Ceejay, Liau, Brian B
Publicado 2023

Chromatin complex dependencies reveal targeting opportunities in leukemia

por Najm, Fadi J., DeWeirdt, Peter, Moore, Molly M., Bevill, Samantha M., El Farran, Chadi A., Macias, Kevin A., Hegde, Mudra, Waterbury, Amanda L., Liau, Brian B., van Galen, Peter, Doench, John G., Bernstein, Bradley E.
Publicado 2023

Transcription elongation factors represent in vivo cancer dependencies in glioblastoma

por Miller, Tyler E., Liau, Brian B., Wallace, Lisa C., Morton, Andrew R., Xie, Qi, Dixit, Deobrat, Factor, Daniel C., Kim, Leo J. Y., Morrow, James J., Wu, Qiulian, Mack, Stephen C., Hubert, Christopher G., Gillespie, Shawn M., Flavahan, William A., Hoffmann, Thomas, Thummalapalli, Rohit, Hemann, Michael T., Paddison, Patrick J., Horbinski, Craig M., Zuber, Johannes, Scacheri, Peter C., Bernstein, Bradley E., Tesar, Paul J., Rich, Jeremy N.
Publicado 2017

Mediator Kinase Inhibition Further Activates Super-Enhancer Associated Genes in AML

por Pelish, Henry E., Liau, Brian B., Nitulescu, Ioana I., Tangpeerachaikul, Anupong, Poss, Zachary C., Da Silva, Diogo H., Caruso, Brittany T., Arefolov, Alexander, Fadeyi, Olugbeminiyi, Christie, Amanda L., Du, Karrie, Banka, Deepti, Schneider, Elisabeth V., Jestel, Anja, Zou, Ge, Si, Chong, Ebmeier, Christopher C., Bronson, Roderick T., Krivtsov, Andrei V., Myers, Andrew G., Kohl, Nancy E., Kung, Andrew L., Armstrong, Scott A., Lemieux, Madeleine E., Taatjes, Dylan J., Shair, Matthew D.
Publicado 2015