Perilipin-2 promotes lipid droplet-plasma membrane interactions that facilitate apocrine lipid secretion in secretory epithelial cells of the mouse mammary gland

por Monks, Jenifer, Orlicky, David J., Libby, Andrew E., Dzieciatkowska, Monica, Ladinsky, Mark S., McManaman, James L.
Publicado 2022

4528 Sirtuin 3 activation as a potential renoprotective therapy in a mouse model of Alport syndrome

por Jones, Bryce, Myakala, Komuraiah, Wang, Xiaoxin, Libby, Andrew, Takahashi, Shogo, Bhasin, Kanchan, Ranjit, Suman, Rosenberg, Avi, Levi, Moshe
Publicado 2020

27558 Obeticholic acid (OCALIVA ®) protects against 2,8-dihydroxyadenine nephropathy in mice

por Jones, Bryce, Benitez, Carlos, Cruz, Idalia, Myakala, Komuraiah, Wang, Xiaoxin, Libby, Andrew, Rowland, Emma, Kurtz, Ryan, Rosenberg, Avi, Levi, Moshe
Publicado 2021

Striated muscle gene therapy for the treatment of lipoprotein lipase deficiency

por Gadek, Katherine E., Wang, Hong, Hall, Monica N., Sungello, Mitchell, Libby, Andrew, MacLaskey, Drew, Eckel, Robert H., Olwin, Bradley B.
Publicado 2018

Neuronal Lipoprotein Lipase Deficiency Alters Neuronal Function and Hepatic Metabolism

por Bruce, Kimberley D., Dobrinskikh, Evgenia, Wang, Hong, Rudenko, Ivan, Gao, Hong, Libby, Andrew E., Gorkhali, Sachi, Yu, Tian, Zsombok, Andrea, Eckel, Robert H.
Publicado 2020

Hematopoietic Stem Cell-Derived Adipocytes Modulate Adipose Tissue Cellularity, Leptin Production and Insulin Responsiveness in Female Mice

por Gavin, Kathleen M., Sullivan, Timothy M., Maltzahn, Joanne K., Jackman, Matthew R., Libby, Andrew E., MacLean, Paul S., Kohrt, Wendy M., Majka, Susan M., Klemm, Dwight J.
Publicado 2022

Discovery of JND003 as a New Selective Estrogen-Related Receptor α Agonist Alleviating Nonalcoholic Fatty Liver Disease and Insulin Resistance

por Mao, Liufeng, Peng, Lijie, Ren, Xiaomei, Chu, Yi, Nie, Tao, Lin, Wanhua, Libby, Andrew, Xu, Yong, Chang, Yu, Lei, Chong, Loomes, Kerry, Wang, Na, Liu, Jinsong, Levi, Moshe, Wu, Donghai, Hui, Xiaoyan, Ding, Ke
Publicado 2022

Maternal obesity during lactation may protect offspring from high fat diet-induced metabolic dysfunction

por Monks, Jenifer, Orlicky, David J., Stefanski, Adrianne L., Libby, Andrew E., Bales, Elise S., Rudolph, Michael C., Johnson, Ginger C., Sherk, Vanessa D., Jackman, Matthew R., Williamson, Kayla, Carlson, Nichole E., MacLean, Paul S., McManaman, James L.
Publicado 2018

Empagliflozin Treatment Attenuates Hepatic Steatosis by Promoting White Adipose Expansion in Obese TallyHo Mice

por Kurtz, Ryan, Libby, Andrew, Jones, Bryce A., Myakala, Komuraiah, Wang, Xiaoxin, Lee, Yichien, Knoer, Grace, Lo Cascio, Julia N., McCormack, Michaela, Nguyen, Grace, Choos, Elijah N. D., Rodriguez, Olga, Rosenberg, Avi Z., Ranjit, Suman, Albanese, Christopher, Levi, Moshe, Ecelbarger, Carolyn M., Shepard, Blythe D.
Publicado 2022

Oral N-acetylcysteine decreases IFN-γ production and ameliorates ischemia-reperfusion injury in steatotic livers

por Liggett, Jedson R., Kang, Jiman, Ranjit, Suman, Rodriguez, Olga, Loh, Katrina, Patil, Digvijay, Cui, Yuki, Duttargi, Anju, Nguyen, Sang, He, Britney, Lee, Yichien, Oza, Kesha, Frank, Brett S., Kwon, DongHyang, Li, Heng-Hong, Kallakury, Bhaskar, Libby, Andrew, Levi, Moshe, Robson, Simon C., Fishbein, Thomas M., Cui, Wanxing, Albanese, Chris, Khan, Khalid, Kroemer, Alexander
Publicado 2022

The role of FXR and TGR5 in reversing and preventing progression of Western diet–induced hepatic steatosis, inflammation, and fibrosis in mice

por Wang, Xiaoxin X., Xie, Cen, Libby, Andrew E., Ranjit, Suman, Levi, Jonathan, Myakala, Komuraiah, Bhasin, Kanchan, Jones, Bryce A., Orlicky, David J., Takahashi, Shogo, Dvornikov, Alexander, Kleiner, David E., Hewitt, Stephen M., Adorini, Luciano, Kopp, Jeffrey B., Krausz, Kristopher W., Rosenberg, Avi, McManaman, James L., Robertson, Charles E., Ir, Diana, Frank, Daniel N., Luo, Yuhuan, Gonzalez, Frank J., Gratton, Enrico, Levi, Moshe
Publicado 2022