Chronic loss of STAG2 leads to altered chromatin structure contributing to de-regulated transcription in AML

por Smith, James S., Lappin, Katrina M., Craig, Stephanie G., Liberante, Fabio G., Crean, Clare M., McDade, Simon S., Thompson, Alexander, Mills, Ken I., Savage, Kienan I.
Publicado 2020

The RNA processing factors THRAP3 and BCLAF1 promote the DNA damage response through selective mRNA splicing and nuclear export

por Vohhodina, Jekaterina, Barros, Eliana M., Savage, Abigail L., Liberante, Fabio G., Manti, Lorenzo, Bankhead, Peter, Cosgrove, Nicola, Madden, Angelina F., Harkin, D. Paul, Savage, Kienan I.
Publicado 2017

Cancer-Associated SF3B1 Mutations Confer a BRCA-Like Cellular Phenotype and Synthetic Lethality to PARP Inhibitors

por Lappin, Katrina M., Barros, Eliana M., Jhujh, Satpal S., Irwin, Gareth W., McMillan, Hayley, Liberante, Fabio G., Latimer, Cheryl, La Bonte, Melissa J., Mills, Ken I., Harkin, D. Paul, Stewart, Grant S., Savage, Kienan I.
Publicado 2022