Function of Deptor and its roles in hematological malignancies

por Morales-Martinez, Mario, Lichtenstein, Alan, Vega, Mario I.
Publicado 2021

Turnover of the mTOR inhibitor, DEPTOR, and downstream AKT phosphorylation in multiple myeloma cells, is dependent on ERK1-mediated phosphorylation

por Vega, Mario, Chen, Yu, Shi, Yijiang, Gera, Joseph, Lichtenstein, Alan
Publicado 2022

MNK1-Induced eIF-4E Phosphorylation in Myeloma Cells: A Pathway Mediating IL-6-Induced Expansion and Expression of Genes Involved in Metabolic and Proteotoxic Responses

por Shi, Yijiang, Frost, Patrick, Hoang, Bao, Yang, Yonghui, Bardeleben, Carolyne, Gera, Joseph, Lichtenstein, Alan
Publicado 2014

Repurposing Potential of Riluzole as an ITAF Inhibitor in mTOR Therapy Resistant Glioblastoma

por Benavides-Serrato, Angelica, Saunders, Jacquelyn T., Holmes, Brent, Nishimura, Robert N., Lichtenstein, Alan, Gera, Joseph
Publicado 2020

Mammalian Target of Rapamycin Inhibitors Induce Tumor Cell Apoptosis In Vivo Primarily by Inhibiting VEGF Expression and Angiogenesis

por Frost, Patrick, Berlanger, Eileen, Mysore, Veena, Hoang, Bao, Shi, YiJiang, Gera, Joseph, Lichtenstein, Alan
Publicado 2013

DEPTOR is linked to a TORC1-p21 survival proliferation pathway in multiple myeloma cells

por Yang, Yonghui, Bardeleben, Carolyne, Frost, Patrick, Hoang, Bao, Shi, Yijiang, Finn, Richard, Gera, Joseph, Lichtenstein, Alan
Publicado 2014

Specific blockade of Rictor-mTOR association inhibits mTORC2 activity and is cytotoxic in glioblastoma

por Benavides-Serrato, Angelica, Lee, Jihye, Holmes, Brent, Landon, Kenna A., Bashir, Tariq, Jung, Michael E., Lichtenstein, Alan, Gera, Joseph
Publicado 2017

Correction: Specific blockade of Rictor-mTOR association inhibits mTORC2 activity and is cytotoxic in glioblastoma

por Benavides-Serrato, Angelica, Lee, Jihye, Holmes, Brent, Landon, Kenna A., Bashir, Tariq, Jung, Michael E., Lichtenstein, Alan, Gera, Joseph
Publicado 2019