Proteomics in neurons and animals: substrates and therapeutic potential of alpha-and beta-secretase

por Lichtenthaler, Stefan
Publicado 2013

The Membrane-Bound Aspartyl Protease BACE1: Molecular and Functional Properties in Alzheimer’s Disease and Beyond

por Dislich, Bastian, Lichtenthaler, Stefan F.
Publicado 2012

Seizure-6 proteins highlight BACE1 functions in neurobiology

por Pigoni, Martina, Gunnersen, Jenny M., Lichtenthaler, Stefan F.
Publicado 2016

Proteomic Substrate Identification for Membrane Proteases in the Brain

por Müller, Stephan A., Scilabra, Simone D., Lichtenthaler, Stefan F.
Publicado 2016

Determination of the Proteolytic Cleavage Sites of the Amyloid Precursor-Like Protein 2 by the Proteases ADAM10, BACE1 and γ-Secretase

por Hogl, Sebastian, Kuhn, Peer-Hendrik, Colombo, Alessio, Lichtenthaler, Stefan F.
Publicado 2011

New Highly Selective BACE1 Inhibitors and Their Effects on Dendritic Spine Density In Vivo

por Pratsch, Katrin, Unemura, Chie, Ito, Mana, Lichtenthaler, Stefan F., Horiguchi, Naotaka, Herms, Jochen
Publicado 2023

Bioinformatics Identification of Modules of Transcription Factor Binding Sites in Alzheimer's Disease-Related Genes by In Silico Promoter Analysis and Microarrays

por Augustin, Regina, Lichtenthaler, Stefan F., Greeff, Michael, Hansen, Jens, Wurst, Wolfgang, Trümbach, Dietrich
Publicado 2011

Functions of the Alzheimer’s Disease Protease BACE1 at the Synapse in the Central Nervous System

por Munro, Kathryn M., Nash, Amelia, Pigoni, Martina, Lichtenthaler, Stefan F., Gunnersen, Jenny M.
Publicado 2016

An Alzheimer‐associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic function

por Schlepckow, Kai, Kleinberger, Gernot, Fukumori, Akio, Feederle, Regina, Lichtenthaler, Stefan F, Steiner, Harald, Haass, Christian
Publicado 2017

Cell Type-Specific Human APP Transgene Expression by Hippocampal Interneurons in the Tg2576 Mouse Model of Alzheimer’s Disease

por Höfling, Corinna, Shehabi, Emira, Kuhn, Peer-Hendrik, Lichtenthaler, Stefan F., Hartlage-Rübsamen, Maike, Roßner, Steffen
Publicado 2019

Increased TIMP-3 expression alters the cellular secretome through dual inhibition of the metalloprotease ADAM10 and ligand-binding of the LRP-1 receptor

por Scilabra, Simone D., Pigoni, Martina, Pravatá, Veronica, Schätzl, Tobias, Müller, Stephan A., Troeberg, Linda, Lichtenthaler, Stefan F.
Publicado 2018

Basic Fibroblast Growth Factor 2-Induced Proteome Changes Endorse Lewy Body Pathology in Hippocampal Neurons

por Kumar, Rohit, Donakonda, Sainitin, Müller, Stephan A., Lichtenthaler, Stefan F., Bötzel, Kai, Höglinger, Günter U., Koeglsperger, Thomas
Publicado 2020

LncRNA RUS shapes the gene expression program towards neurogenesis

por Schneider, Marius F, Müller, Veronika, Müller, Stephan A, Lichtenthaler, Stefan F, Becker, Peter B, Scheuermann, Johanna C
Publicado 2022

A microglial activity state biomarker panel differentiates FTD-granulin and Alzheimer’s disease patients from controls

por Pesämaa, Ida, Müller, Stephan A., Robinson, Sophie, Darcher, Alana, Paquet, Dominik, Zetterberg, Henrik, Lichtenthaler, Stefan F., Haass, Christian
Publicado 2023

Computational identification and experimental validation of microRNAs binding to the Alzheimer-related gene ADAM10

por Augustin, Regina, Endres, Kristina, Reinhardt, Sven, Kuhn, Peer-Hendrik, Lichtenthaler, Stefan F, Hansen, Jens, Wurst, Wolfgang, Trümbach, Dietrich
Publicado 2012

BACE1 Inhibitor MK-8931 Alters Formation but Not Stability of Dendritic Spines

por Blume, Tanja, Filser, Severin, Jaworska, Anna, Blain, Jean-Francois, Koenig, Gerhard, Moschke, Katrin, Lichtenthaler, Stefan F., Herms, Jochen
Publicado 2018

Amyloid-Beta Mediates Homeostatic Synaptic Plasticity

por Galanis, Christos, Fellenz, Meike, Becker, Denise, Bold, Charlotte, Lichtenthaler, Stefan F., Müller, Ulrike C., Deller, Thomas, Vlachos, Andreas
Publicado 2021

QARIP: a web server for quantitative proteomic analysis of regulated intramembrane proteolysis

por Ivankov, Dmitry N., Bogatyreva, Natalya S., Hönigschmid, Peter, Dislich, Bastian, Hogl, Sebastian, Kuhn, Peer-Hendrik, Frishman, Dmitrij, Lichtenthaler, Stefan F.
Publicado 2013

BACE2 distribution in major brain cell types and identification of novel substrates

por Voytyuk, Iryna, Mueller, Stephan A, Herber, Julia, Snellinx, An, Moechars, Dieder, van Loo, Geert, Lichtenthaler, Stefan F, De Strooper, Bart
Publicado 2018

NrCAM is a marker for substrate‐selective activation of ADAM10 in Alzheimer's disease

por Brummer, Tobias, Müller, Stephan A, Pan‐Montojo, Francisco, Yoshida, Fumiaki, Fellgiebel, Andreas, Tomita, Taisuke, Endres, Kristina, Lichtenthaler, Stefan F
Publicado 2019