Safety, Pharmacokinetics, and Drug-Drug Interaction Potential of Intravenous Durlobactam, a β-Lactamase Inhibitor, in Healthy Subjects

por Lickliter, Jason D., Lawrence, Kenneth, O’Donnell, John, Isaacs, Robin
Publicado 2020

Phase I dose-escalation study to determine the safety, tolerability, preliminary efficacy and pharmacokinetics of an intratumoral injection of tigilanol tiglate (EBC-46)

por Panizza, Benedict J., de Souza, Paul, Cooper, Adam, Roohullah, Aflah, Karapetis, Christos S., Lickliter, Jason D.
Publicado 2019

A randomized, double-blind, parallel-group, single-dose comparative pharmacokinetic study of DRL_TZ, a candidate biosimilar of trastuzumab, with Herceptin(®) (EU) in healthy adult...

por Lickliter, Jason D., Dadhania, Rakesh Naranbhai, Trivedi, Ravi Kumar, Kumar, S.R. Naveen, Reddy, Pramod Kumar
Publicado 2021

A Randomized, Double-Blinded, Placebo-Controlled, Dose-Escalation Phase 1 Study of Aerosolized Pirfenidone Delivered via the PARI Investigational eFlow Nebulizer in Volunteers and...

por Khoo, Jun Keng, Montgomery, A. Bruce, Otto, Kelly L., Surber, Mark, Faggian, Jessica, Lickliter, Jason D., Glaspole, Ian
Publicado 2020

Correction: Phase 1A/1B dose-escalation and -expansion study to evaluate the safety, pharmacokinetics, food effects and antitumor activity of pamiparib in advanced solid tumours

por Lickliter, Jason D., Voskoboynik, Mark, Mileshkin, Linda, Gan, Hui K., Kichenadasse, Ganessan, Zhang, Kathy, Zhang, Maggie, Tang, Zhiyu, Millward, Michael
Publicado 2021

Phase 1A/1B dose-escalation and -expansion study to evaluate the safety, pharmacokinetics, food effects and antitumor activity of pamiparib in advanced solid tumours

por Lickliter, Jason D., Voskoboynik, Mark, Mileshkin, Linda, Gan, Hui K., Kichenadasse, Ganessan, Zhang, Kathy, Zhang, Maggie, Tang, Zhiyu, Millward, Michael
Publicado 2021

Dodecafluoropentane Emulsion as a Radiosensitizer in Glioblastoma Multiforme

por Lickliter, Jason D., Ruben, Jeremy, Kichenadasse, Ganessan, Jennens, Ross, Gzell, Cecelia, Mason, Ralph P., Zhou, Heling, Becker, Jennifer, Unger, Evan, Stea, Baldassarre
Publicado 2023

Safety, Pharmacokinetics, and Clinical Activity of Adavosertib in Combination with Chemotherapy in Asian Patients with Advanced Solid Tumors: Phase Ib Study

por Kato, Hidenori, de Souza, Paul, Kim, Sang-We, Lickliter, Jason D., Naito, Yoichi, Park, Keunchil, Kumar, Sanjeev, Mugundu, Ganesh M., Bang, Yung-Jue
Publicado 2020

A Phase I study of the novel immunomodulatory agent PG545 (pixatimod) in subjects with advanced solid tumours

por Dredge, Keith, Brennan, Todd V., Hammond, Edward, Lickliter, Jason D., Lin, Liwen, Bampton, Darryn, Handley, Paul, Lankesheer, Fleur, Morrish, Glynn, Yang, Yiping, Brown, Michael P., Millward, Michael
Publicado 2018

First‐in‐human study of the safety, tolerability, pharmacokinetics, and pharmacodynamics of ALPN‐101, a dual CD28/ICOS antagonist, in healthy adult subjects

por Yang, Jing, Lickliter, Jason D., Hillson, Jan L., Means, Gary D., Sanderson, Russell J., Carley, Kay, Tercero, Almudena, Manjarrez, Kristi L., Wiley, Jennifer R., Peng, Stanford L.
Publicado 2021

A phase 1 clinical trial of the sigma-2 receptor complex allosteric antagonist CT1812, a novel therapeutic candidate for Alzheimer's disease

por Grundman, Michael, Morgan, Roger, Lickliter, Jason D., Schneider, Lon S., DeKosky, Steven, Izzo, Nicholas J., Guttendorf, Robert, Higgin, Michelle, Pribyl, Julie, Mozzoni, Kelsie, Safferstein, Hank, Catalano, Susan M.
Publicado 2019

Cellular responses at the application site of a high-density microarray patch delivering an influenza vaccine in a randomized, controlled phase I clinical trial

por Depelsenaire, Alexandra C. I., Witham, Katey, Veitch, Margaret, Wells, James W., Anderson, Christopher D., Lickliter, Jason D., Rockman, Steve, Bodle, Jesse, Treasure, Peter, Hickling, Julian, Fernando, Germain J. P., Forster, Angus H.
Publicado 2021

Safety and Immunogenicity of 3 Formulations of an Investigational Respiratory Syncytial Virus Vaccine in Nonpregnant Women: Results From 2 Phase 2 Trials

por Beran, Jiři, Lickliter, Jason D, Schwarz, Tino F, Johnson, Casey, Chu, Laurence, Domachowske, Joseph B, Van Damme, Pierre, Withanage, Kanchanamala, Fissette, Laurence A, David, Marie-Pierre, Maleux, Koen, Schmidt, Alexander C, Picciolato, Marta, Dieussaert, Ilse
Publicado 2018

Safety, tolerability, and immunogenicity of influenza vaccination with a high-density microarray patch: Results from a randomized, controlled phase I clinical trial

por Forster, Angus H., Witham, Katey, Depelsenaire, Alexandra C. I., Veitch, Margaret, Wells, James W., Wheatley, Adam, Pryor, Melinda, Lickliter, Jason D., Francis, Barbara, Rockman, Steve, Bodle, Jesse, Treasure, Peter, Hickling, Julian, Fernando, Germain J. P.
Publicado 2020

A First-in-Human Dose Finding Study of Camrelizumab in Patients with Advanced or Metastatic Cancer in Australia

por Lickliter, Jason D, Gan, Hui K, Voskoboynik, Mark, Arulananda, Surein, Gao, Bo, Nagrial, Adnan, Grimison, Peter, Harrison, Michelle, Zou, Jianjun, Zhang, Lianshan, Luo, Stacey, Lahn, Michael, Kallender, Howard, Mannucci, Andrea, Somma, Catello, Woods, Katherine, Behren, Andreas, Fernandez-Penas, Pablo, Millward, Michael, Meniawy, Tarek
Publicado 2020

A Phase I, First‐in‐Human Study of GSK2849330, an Anti‐HER3 Monoclonal Antibody, in HER3‐Expressing Solid Tumors

por Gan, Hui K., Millward, Michael, Jalving, Mathilde, Garrido‐Laguna, Ignacio, Lickliter, Jason D., Schellens, Jan H.M., Lolkema, Martijn P., Van Herpen, Carla L.M., Hug, Bruce, Tang, Lihua, O'Connor‐Semmes, Robin, Gagnon, Robert, Ellis, Catherine, Ganji, Gopinath, Matheny, Christopher, Drilon, Alexander
Publicado 2021

Phase 1–2 Trial of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine

por Keech, Cheryl, Albert, Gary, Cho, Iksung, Robertson, Andreana, Reed, Patricia, Neal, Susan, Plested, Joyce S., Zhu, Mingzhu, Cloney-Clark, Shane, Zhou, Haixia, Smith, Gale, Patel, Nita, Frieman, Matthew B., Haupt, Robert E., Logue, James, McGrath, Marisa, Weston, Stuart, Piedra, Pedro A., Desai, Chinar, Callahan, Kathleen, Lewis, Maggie, Price-Abbott, Patricia, Formica, Neil, Shinde, Vivek, Fries, Louis, Lickliter, Jason D., Griffin, Paul, Wilkinson, Bethanie, Glenn, Gregory M.
Publicado 2020