Human pluripotent stem cells for the modelling of retinal pigment epithelium homeostasis and disease: A review

por Hall, Jenna C, Paull, Daniel, Pébay, Alice, Lidgerwood, Grace E.
Publicado 2022

Altered biometal homeostasis is associated with CLN6 mRNA loss in mouse neuronal ceroid lipofuscinosis

por Kanninen, Katja M., Grubman, Alexandra, Caragounis, Aphrodite, Duncan, Clare, Parker, Sarah J., Lidgerwood, Grace E., Volitakis, Irene, Ganio, George, Crouch, Peter J., White, Anthony R.
Publicado 2013

Engineering domain-inlaid SaCas9 adenine base editors with reduced RNA off-targets and increased on-target DNA editing

por Nguyen Tran, Minh Thuan, Mohd Khalid, Mohd Khairul Nizam, Wang, Qi, Walker, Jacqueline K. R., Lidgerwood, Grace E., Dilworth, Kimberley L., Lisowski, Leszek, Pébay, Alice, Hewitt, Alex W.
Publicado 2020

Transcriptomic Profiling of Human Pluripotent Stem Cell-derived Retinal Pigment Epithelium over Time

por Lidgerwood, Grace E., Senabouth, Anne, Smith-Anttila, Casey J.A., Gnanasambandapillai, Vikkitharan, Kaczorowski, Dominik C., Amann-Zalcenstein, Daniela, Fletcher, Erica L., Naik, Shalin H., Hewitt, Alex W., Powell, Joseph E., Pébay, Alice
Publicado 2021

Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress

por Moujalled, Diane, James, Janine L., Parker, Sarah J., Lidgerwood, Grace E., Duncan, Clare, Meyerowitz, Jodi, Nonaka, Takashi, Hasegawa, Masato, Kanninen, Katja M., Grubman, Alexandra, Liddell, Jeffrey R., Crouch, Peter J., White, Anthony R.
Publicado 2013

Enriched retinal ganglion cells derived from human embryonic stem cells

por Gill, Katherine P., Hung, Sandy S. C., Sharov, Alexei, Lo, Camden Y., Needham, Karina, Lidgerwood, Grace E., Jackson, Stacey, Crombie, Duncan E., Nayagam, Bryony A., Cook, Anthony L., Hewitt, Alex W., Pébay, Alice, Wong, Raymond C. B.
Publicado 2016

AAV2-mediated gene therapy for Bietti crystalline dystrophy provides functional CYP4V2 in multiple relevant cell models

por Wang, Jiang-Hui, Lidgerwood, Grace E., Daniszewski, Maciej, Hu, Monica L., Roberts, Georgina E., Wong, Raymond C. B., Hung, Sandy S. C., McClements, Michelle E., Hewitt, Alex W., Pébay, Alice, Hickey, Doron G., Edwards, Thomas L.
Publicado 2022

A novel role for the Pol I transcription factor UBTF in maintaining genome stability through the regulation of highly transcribed Pol II genes

por Sanij, Elaine, Diesch, Jeannine, Lesmana, Analia, Poortinga, Gretchen, Hein, Nadine, Lidgerwood, Grace, Cameron, Donald P., Ellul, Jason, Goodall, Gregory J., Wong, Lee H., Dhillon, Amardeep S., Hamdane, Nourdine, Rothblum, Lawrence I., Pearson, Richard B., Haviv, Izhak, Moss, Tom, Hannan, Ross D.
Publicado 2015

Single cell eQTL analysis identifies cell type-specific genetic control of gene expression in fibroblasts and reprogrammed induced pluripotent stem cells

por Neavin, Drew, Nguyen, Quan, Daniszewski, Maciej S., Liang, Helena H., Chiu, Han Sheng, Wee, Yong Kiat, Senabouth, Anne, Lukowski, Samuel W., Crombie, Duncan E., Lidgerwood, Grace E., Hernández, Damián, Vickers, James C., Cook, Anthony L., Palpant, Nathan J., Pébay, Alice, Hewitt, Alex W., Powell, Joseph E.
Publicado 2021

Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder

por Grubman, Alexandra, Lidgerwood, Grace E, Duncan, Clare, Bica, Laura, Tan, Jiang-Li, Parker, Sarah J, Caragounis, Aphrodite, Meyerowitz, Jodi, Volitakis, Irene, Moujalled, Diane, Liddell, Jeffrey R, Hickey, James L, Horne, Malcolm, Longmuir, Shoshanah, Koistinaho, Jari, Donnelly, Paul S, Crouch, Peter J, Tammen, Imke, White, Anthony R, Kanninen, Katja M
Publicado 2014

A village in a dish model system for population-scale hiPSC studies

por Neavin, Drew R., Steinmann, Angela M., Farbehi, Nona, Chiu, Han Sheng, Daniszewski, Maciej S., Arora, Himanshi, Bermudez, Yasmin, Moutinho, Cátia, Chan, Chia-Ling, Bax, Monique, Tyebally, Mubarika, Gnanasambandapillai, Vikkitharan, Lam, Chuan E., Nguyen, Uyen, Hernández, Damián, Lidgerwood, Grace E., Graham, Robert M., Hewitt, Alex W., Pébay, Alice, Palpant, Nathan J., Powell, Joseph E.
Publicado 2023

Single-Cell Profiling Identifies Key Pathways Expressed by iPSCs Cultured in Different Commercial Media

por Daniszewski, Maciej, Nguyen, Quan, Chy, Hun S., Singh, Vikrant, Crombie, Duncan E., Kulkarni, Tejal, Liang, Helena H., Sivakumaran, Priyadharshini, Lidgerwood, Grace E., Hernández, Damián, Conquest, Alison, Rooney, Louise A., Chevalier, Sophie, Andersen, Stacey B., Senabouth, Anne, Vickers, James C., Mackey, David A., Craig, Jamie E., Laslett, Andrew L., Hewitt, Alex W., Powell, Joseph E., Pébay, Alice
Publicado 2018

Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma

por Daniszewski, Maciej, Senabouth, Anne, Liang, Helena H., Han, Xikun, Lidgerwood, Grace E., Hernández, Damián, Sivakumaran, Priyadharshini, Clarke, Jordan E., Lim, Shiang Y., Lees, Jarmon G., Rooney, Louise, Gulluyan, Lerna, Souzeau, Emmanuelle, Graham, Stuart L., Chan, Chia-Ling, Nguyen, Uyen, Farbehi, Nona, Gnanasambandapillai, Vikkitharan, McCloy, Rachael A., Clarke, Linda, Kearns, Lisa S., Mackey, David A., Craig, Jamie E., MacGregor, Stuart, Powell, Joseph E., Pébay, Alice, Hewitt, Alex W.
Publicado 2022

Transcriptomic and proteomic retinal pigment epithelium signatures of age-related macular degeneration

por Senabouth, Anne, Daniszewski, Maciej, Lidgerwood, Grace E., Liang, Helena H., Hernández, Damián, Mirzaei, Mehdi, Keenan, Stacey N., Zhang, Ran, Han, Xikun, Neavin, Drew, Rooney, Louise, Lopez Sanchez, Maria Isabel G., Gulluyan, Lerna, Paulo, Joao A., Clarke, Linda, Kearns, Lisa S., Gnanasambandapillai, Vikkitharan, Chan, Chia-Ling, Nguyen, Uyen, Steinmann, Angela M., McCloy, Rachael A., Farbehi, Nona, Gupta, Vivek K., Mackey, David A., Bylsma, Guy, Verma, Nitin, MacGregor, Stuart, Watt, Matthew J., Guymer, Robyn H., Powell, Joseph E., Hewitt, Alex W., Pébay, Alice
Publicado 2022