Pluripotent Stem Cells for Disease Modeling and Drug Discovery in Niemann-Pick Type C1

por Völkner, Christin, Liedtke, Maik, Hermann, Andreas, Frech, Moritz J.
Publicado 2021

Impact of Organelle Transport Deficits on Mitophagy and Autophagy in Niemann–Pick Disease Type C

por Liedtke, Maik, Völkner, Christin, Hermann, Andreas, Frech, Moritz J.
Publicado 2022

Patient-Specific iPSC-Derived Neural Differentiated and Hepatocyte-like Cells, Carrying the Compound Heterozygous Mutation p.V1023Sfs*15/p.G992R, Present the “Variant” Biochemical...

por Völkner, Christin, Liedtke, Maik, Untucht, Robert, Hermann, Andreas, Frech, Moritz J.
Publicado 2021

Assessment of FDA-Approved Drugs as a Therapeutic Approach for Niemann-Pick Disease Type C1 Using Patient-Specific iPSC-Based Model Systems

por Völkner, Christin, Pantoom, Supansa, Liedtke, Maik, Lukas, Jan, Hermann, Andreas, Frech, Moritz J.
Publicado 2022

Oxidative Stress and Alterations in the Antioxidative Defense System in Neuronal Cells Derived from NPC1 Patient-Specific Induced Pluripotent Stem Cells

por Jürs, Alexandra V., Völkner, Christin, Liedtke, Maik, Huth, Katharina, Lukas, Jan, Hermann, Andreas, Frech, Moritz J.
Publicado 2020

Pathophysiological In Vitro Profile of Neuronal Differentiated Cells Derived from Niemann-Pick Disease Type C2 Patient-Specific iPSCs Carrying the NPC2 Mutations c.58G>T/c.140G>T

por Liedtke, Maik, Völkner, Christin, Jürs, Alexandra V., Peter, Franziska, Rabenstein, Michael, Hermann, Andreas, Frech, Moritz J.
Publicado 2021