Mycoplasmas and cancer: focus on nucleoside metabolism

por Vande Voorde, Johan, Balzarini, Jan, Liekens, Sandra
Publicado 2014

Synthesis and Biological Evaluation of Analogs of Didehydroepiandrosterone as Potential New Anticancer Agents

por J. Solum, Eirik, Liekens, Sandra, Hansen, Trond Vidar
Publicado 2020

Mycoplasma hyorhinis-encoded cytidine deaminase efficiently inactivates cytosine-based anticancer drugs

por Vande Voorde, Johan, Vervaeke, Peter, Liekens, Sandra, Balzarini, Jan
Publicado 2015

Sulfated Escherichia coli K5 Polysaccharide Derivatives Inhibit Dengue Virus Infection of Human Microvascular Endothelial Cells by Interacting with the Viral Envelope Protein E Dom...

por Vervaeke, Peter, Alen, Marijke, Noppen, Sam, Schols, Dominique, Oreste, Pasqua, Liekens, Sandra
Publicado 2013

2-Amino-3-methylcarboxy-5-heptyl-thiophene (TJ191) is a selective anti-cancer small molecule that targets low TβRIII-expressing malignant T-cell leukemia/lymphoma cells

por El-Gazzar, Ahmed, Noppen, Sam, Thomas, Joice, Dehaen, Wim, Balzarini, Jan, Liekens, Sandra
Publicado 2017

The broad-spectrum anti-DNA virus agent cidofovir inhibits lung metastasis of virus-independent, FGF2-driven tumors

por Liekens, Sandra, Noppen, Sam, Gijsbers, Sofie, Sienaert, Rebecca, Ronca, Roberto, Tobia, Chiara, Presta, Marco
Publicado 2014

Design, Synthesis, Spectroscopic Characterisation and In Vitro Cytostatic Evaluation of Novel Bis(coumarin-1,2,3-triazolyl)benzenes and Hybrid Coumarin-1,2,3-triazolyl-aryl Derivat...

por Pršir, Kristina, Horak, Ema, Kralj, Marijeta, Uzelac, Lidija, Liekens, Sandra, Steinberg, Ivana Murković, Krištafor, Svjetlana
Publicado 2022

Synthesis of a 3′-C-ethynyl-β-d-ribofuranose purine nucleoside library: Discovery of C7-deazapurine analogs as potent antiproliferative nucleosides

por Hulpia, Fabian, Noppen, Sam, Schols, Dominique, Andrei, Graciela, Snoeck, Robert, Liekens, Sandra, Vervaeke, Peter, Van Calenbergh, Serge
Publicado 2018

Design, Synthesis and Evaluation of Antiproliferative Activity of New Benzimidazolehydrazones

por Onnis, Valentina, Demurtas, Monica, Deplano, Alessandro, Balboni, Gianfranco, Baldisserotto, Anna, Manfredini, Stefano, Pacifico, Salvatore, Liekens, Sandra, Balzarini, Jan
Publicado 2016

Skin Damages—Structure Activity Relationship of Benzimidazole Derivatives Bearing a 5-Membered Ring System

por Djuidje, Ernestine Nicaise, Durini, Elisa, Sciabica, Sabrina, Serra, Elena, Balzarini, Jan, Liekens, Sandra, Manfredini, Stefano, Vertuani, Silvia, Baldisserotto, Anna
Publicado 2020

Benzothiazole Derivatives as Multifunctional Antioxidant Agents for Skin Damage: Structure–Activity Relationship of a Scaffold Bearing a Five-Membered Ring System

por Djuidje, Ernestine Nicaise, Barbari, Riccardo, Baldisserotto, Anna, Durini, Elisa, Sciabica, Sabrina, Balzarini, Jan, Liekens, Sandra, Vertuani, Silvia, Manfredini, Stefano
Publicado 2022

The Cellular Thioredoxin-1/Thioredoxin Reductase-1 Driven Oxidoreduction Represents a Chemotherapeutic Target for HIV-1 Entry Inhibition

por Reiser, Kathrin, Mathys, Leen, Curbo, Sophie, Pannecouque, Christophe, Noppen, Sam, Liekens, Sandra, Engman, Lars, Lundberg, Mathias, Balzarini, Jan, Karlsson, Anna
Publicado 2016

Signal Peptide-Binding Drug as a Selective Inhibitor of Co-Translational Protein Translocation

por Vermeire, Kurt, Bell, Thomas W., Van Puyenbroeck, Victor, Giraut, Anne, Noppen, Sam, Liekens, Sandra, Schols, Dominique, Hartmann, Enno, Kalies, Kai-Uwe, Marsh, Mark
Publicado 2014

Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3′,4′,5′-trimethoxyphenyl)-3-(2′-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtai...

por Preti, Delia, Romagnoli, Romeo, Rondanin, Riccardo, Cacciari, Barbara, Hamel, Ernest, Balzarini, Jan, Liekens, Sandra, Schols, Dominique, Estévez-Sarmiento, Francisco, Quintana, José, Estévez, Francisco
Publicado 2018

Zebrafish Bioassay-Guided Natural Product Discovery: Isolation of Angiogenesis Inhibitors from East African Medicinal Plants

por Crawford, Alexander D., Liekens, Sandra, Kamuhabwa, Appolinary R., Maes, Jan, Munck, Sebastian, Busson, Roger, Rozenski, Jef, Esguerra, Camila V., de Witte, Peter A. M.
Publicado 2011

Carbohydrate-Binding Non-Peptidic Pradimicins for the Treatment of Acute Sleeping Sickness in Murine Models

por Castillo-Acosta, Víctor M., Ruiz-Pérez, Luis M., Etxebarria, Juan, Reichardt, Niels C., Navarro, Miguel, Igarashi, Yasuhiro, Liekens, Sandra, Balzarini, Jan, González-Pacanowska, Dolores
Publicado 2016

Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3′,4′,5′-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold

por Romagnoli, Romeo, Prencipe, Filippo, Oliva, Paola, Cacciari, Barbara, Balzarini, Jan, Liekens, Sandra, Hamel, Ernest, Brancale, Andrea, Ferla, Salvatore, Manfredini, Stefano, Zurlo, Matteo, Finotti, Alessia, Gambari, Roberto
Publicado 2020

A Multi-targeted Drug Candidate with Dual Anti-HIV and Anti-HSV Activity

por Balzarini, Jan, Andrei, Graciela, Balestra, Emanuela, Huskens, Dana, Vanpouille, Christophe, Introini, Andrea, Zicari, Sonia, Liekens, Sandra, Snoeck, Robert, Holý, Antonín, Perno, Carlo-Federico, Margolis, Leonid, Schols, Dominique
Publicado 2013

High mannose-specific lectin Msl mediates key interactions of the vaginal Lactobacillus plantarum isolate CMPG5300

por Malik, Shweta, Petrova, Mariya I., Imholz, Nicole C. E., Verhoeven, Tine L. A., Noppen, Sam, Van Damme, Els J. M., Liekens, Sandra, Balzarini, Jan, Schols, Dominique, Vanderleyden, Jos, Lebeer, Sarah
Publicado 2016

Potent antiviral activity of carbohydrate-specific algal and leguminous lectins from the Brazilian biodiversity

por Gondim, Ana C. S., Roberta da Silva, Suzete, Mathys, Leen, Noppen, Sam, Liekens, Sandra, Holanda Sampaio, Alexandre, Nagano, Celso S., Renata Costa Rocha, Cintia, Nascimento, Kyria S., Cavada, Benildo S., Sadler, Peter J., Balzarini, Jan
Publicado 2019