The molecular mechanisms and pharmacotherapy of ATP-sensitive potassium channel gene mutations underlying neonatal diabetes

por Lang, Veronica, Light, Peter E
Publicado 2010

Evidence for the existence and potential roles of intra-islet glucagon-like peptide-1

por Campbell, Scott A., Johnson, Janyne, Light, Peter E.
Publicado 2021

Non-invasive continuous-time glucose monitoring system using a chipless printable sensor based on split ring microwave resonators

por Baghelani, Masoud, Abbasi, Zahra, Daneshmand, Mojgan, Light, Peter E.
Publicado 2020

The ATP-Sensitive K(+) Channel ABCC8 S1369A Type 2 Diabetes Risk Variant Increases MgATPase Activity

por Fatehi, Mohammad, Raja, Mobeen, Carter, Christian, Soliman, Daniel, Holt, Andrew, Light, Peter E.
Publicado 2012

Intracellular Long-Chain Acyl CoAs Activate TRPV1 Channels

por Yu, Yi, Carter, Chris R. J., Youssef, Nermeen, Dyck, Jason R. B., Light, Peter E.
Publicado 2014

Molecular determinants of ATP-sensitive potassium channel MgATPase activity: diabetes risk variants and diazoxide sensitivity

por Fatehi, Mohammad, Carter, Chris R.J., Youssef, Nermeen, Hunter, Beth E., Holt, Andrew, Light, Peter E.
Publicado 2015

Coexpression of the Type 2 Diabetes Susceptibility Gene Variants KCNJ11 E23K and ABCC8 S1369A Alter the ATP and Sulfonylurea Sensitivities of the ATP-Sensitive K(+) Channel

por Hamming, Kevin S.C., Soliman, Daniel, Matemisz, Laura C., Niazi, Omid, Lang, Yiqiao, Gloyn, Anna L., Light, Peter E.
Publicado 2009

Ischemia induced peroxynitrite dependent modifications of cardiomyocyte MLC1 increases its degradation by MMP-2 leading to contractile dysfunction

por Polewicz, Dorota, Cadete, Virgilio J J, Doroszko, Adrian, Hunter, Beth E, Sawicka, Jolanta, Szczesna-Cordary, Danuta, Light, Peter E, Sawicki, Grzegorz
Publicado 2011

Human islets contain a subpopulation of glucagon-like peptide-1 secreting α cells that is increased in type 2 diabetes

por Campbell, Scott A., Golec, Dominic P., Hubert, Matt, Johnson, Janyne, Salamon, Nicole, Barr, Amy, MacDonald, Patrick E., Philippaert, Koenraad, Light, Peter E.
Publicado 2020

Selective enhancement of cardiomyocyte efficiency results in a pernicious heart condition

por Groenendyk, Jody, Wang, Qian, Wagg, Cory, Lee, Dukgyu, Robinson, Alison, Barr, Amy, Light, Peter E., Lopaschuk, Gary D., Agellon, Luis B., Michalak, Marek
Publicado 2020

Subcutaneous white adipocytes express a light sensitive signaling pathway mediated via a melanopsin/TRPC channel axis

por Ondrusova, Katarina, Fatehi, Mohammad, Barr, Amy, Czarnecka, Zofia, Long, Wentong, Suzuki, Kunimasa, Campbell, Scott, Philippaert, Koenraad, Hubert, Matthew, Tredget, Edward, Kwan, Peter, Touret, Nicolas, Wabitsch, Martin, Lee, Kevin Y., Light, Peter E.
Publicado 2017

Calreticulin Induces Dilated Cardiomyopathy

por Lee, Dukgyu, Oka, Tatsujiro, Hunter, Beth, Robinson, Alison, Papp, Sylvia, Nakamura, Kimitoshi, Srisakuldee, Wattamon, Nickel, Barbara E., Light, Peter E., Dyck, Jason R. B., Lopaschuk, Gary D., Kardami, Elissavet, Opas, Michal, Michalak, Marek
Publicado 2013

Correction: Calreticulin Induces Dilated Cardiomyopathy

por Lee, Dukgyu, Oka, Tatsujiro, Hunter, Beth, Robinson, Alison, Papp, Sylvia, Nakamura, Kimitoshi, Srisakuldee, Wattamon, Nickel, Barbara E., Light, Peter E., Dyck, Jason R. B., Lopaschuk, Gary D., Kardami, Elissavet, Opas, Michal, Michalak, Marek
Publicado 2013

Hypothalamic Protein Kinase C Regulates Glucose Production

por Ross, Rachel, Wang, Penny Y.T., Chari, Madhu, Lam, Carol K.L., Caspi, Liora, Ono, Hiraku, Muse, Evan D., Li, Xiaosong, Gutierrez-Juarez, Roger, Light, Peter E., Schwartz, Gary J., Rossetti, Luciano, Lam, Tony K.T.
Publicado 2008

Direct Binding between Pre-S1 and TRP-like Domains in TRPP Channels Mediates Gating and Functional Regulation by PIP2

por Zheng, Wang, Cai, Ruiqi, Hofmann, Laura, Nesin, Vasyl, Hu, Qiaolin, Long, Wentong, Fatehi, Mohammad, Liu, Xiong, Hussein, Shaimaa, Kong, Tim, Li, Jingru, Light, Peter E., Tang, Jingfeng, Flockerzi, Veit, Tsiokas, Leonidas, Chen, Xing-Zhen
Publicado 2018

Vitamin D is an endogenous partial agonist of the transient receptor potential vanilloid 1 channel

por Long, Wentong, Fatehi, Mohammad, Soni, Shubham, Panigrahi, Rashmi, Philippaert, Koenraad, Yu, Yi, Kelly, Rees, Boonen, Brett, Barr, Amy, Golec, Dominic, Campbell, Scott A., Ondrusova, Katarina, Hubert, Matt, Baldwin, Troy, Lemieux, M. Joanne, Light, Peter E.
Publicado 2020

Inhibition of β-Cell Sodium-Calcium Exchange Enhances Glucose-Dependent Elevations in Cytoplasmic Calcium and Insulin Secretion

por Hamming, Kevin S.C., Soliman, Daniel, Webster, Nicola J., Searle, Gavin J., Matemisz, Laura C., Liknes, David A., Dai, Xiao-Qing, Pulinilkunnil, Thomas, Riedel, Michael J., Dyck, Jason R.B., MacDonald, Patrick E., Light, Peter E.
Publicado 2010

Alterations in Skeletal Muscle Fatty Acid Handling Predisposes Middle-Aged Mice to Diet-Induced Insulin Resistance

por Koonen, Debby P.Y., Sung, Miranda M.Y., Kao, Cindy K.C., Dolinsky, Vernon W., Koves, Timothy R., Ilkayeva, Olga, Jacobs, René L., Vance, Dennis E., Light, Peter E., Muoio, Deborah M., Febbraio, Maria, Dyck, Jason R.B.
Publicado 2010

Cardiac Late Sodium Channel Current Is a Molecular Target for the Sodium/Glucose Cotransporter 2 Inhibitor Empagliflozin

por Philippaert, Koenraad, Kalyaanamoorthy, Subha, Fatehi, Mohammad, Long, Wentong, Soni, Shubham, Byrne, Nikole J., Barr, Amy, Singh, Jyoti, Wong, Jordan, Palechuk, Taylor, Schneider, Chloe, Darwesh, Ahmed M., Maayah, Zaid H., Seubert, John M., Barakat, Khaled, Dyck, Jason R.B., Light, Peter E.
Publicado 2021

Islet Cholesterol Accumulation Due to Loss of ABCA1 Leads to Impaired Exocytosis of Insulin Granules

por Kruit, Janine K., Wijesekara, Nadeeja, Fox, Jocelyn E. Manning, Dai, Xiao-Qing, Brunham, Liam R., Searle, Gavin J., Morgan, Garry P., Costin, Adam J., Tang, Renmei, Bhattacharjee, Alpana, Johnson, James D., Light, Peter E., Marsh, Brad J., MacDonald, Patrick E., Verchere, C. Bruce, Hayden, Michael R.
Publicado 2011