A novel mode of nuclease action is revealed by the bacterial Mre11/Rad50 complex

por Lim, Chew Theng, Lai, Pey Jiun, Leach, David R. F., Maki, Hisaji, Furukohri, Asako
Publicado 2015

Rad50 zinc hook functions as a constitutive dimerization module interchangeable with SMC hinge

por Tatebe, Hisashi, Lim, Chew Theng, Konno, Hiroki, Shiozaki, Kazuhiro, Shinohara, Akira, Uchihashi, Takayuki, Furukohri, Asako
Publicado 2020

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp3 papain-like protease

por Lim, Chew Theng, Tan, Kang Wei, Wu, Mary, Ulferts, Rachel, Armstrong, Lee A., Ozono, Eiko, Drury, Lucy S., Milligan, Jennifer C., Zeisner, Theresa U., Zeng, Jingkun, Weissmann, Florian, Canal, Berta, Bineva-Todd, Ganka, Howell, Michael, O'Reilly, Nicola, Beale, Rupert, Kulathu, Yogesh, Labib, Karim, Diffley, John F.X.
Publicado 2021

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase

por Basu, Souradeep, Mak, Tiffany, Ulferts, Rachel, Wu, Mary, Deegan, Tom, Fujisawa, Ryo, Tan, Kang Wei, Lim, Chew Theng, Basier, Clovis, Canal, Berta, Curran, Joseph F., Drury, Lucy S., McClure, Allison W., Roberts, Emma L., Weissmann, Florian, Zeisner, Theresa U., Beale, Rupert, Cowling, Victoria H., Howell, Michael, Labib, Karim, Diffley, John F.X.
Publicado 2021

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp5 main protease

por Milligan, Jennifer C., Zeisner, Theresa U., Papageorgiou, George, Joshi, Dhira, Soudy, Christelle, Ulferts, Rachel, Wu, Mary, Lim, Chew Theng, Tan, Kang Wei, Weissmann, Florian, Canal, Berta, Fujisawa, Ryo, Deegan, Tom, Nagaraj, Hema, Bineva-Todd, Ganka, Basier, Clovis, Curran, Joseph F., Howell, Michael, Beale, Rupert, Labib, Karim, O'Reilly, Nicola, Diffley, John F.X.
Publicado 2021