Beyond just a tight fortress: contribution of stroma to epithelial-mesenchymal transition in pancreatic cancer

por Bulle, Ashenafi, Lim, Kian-Huat
Publicado 2020

Evolving Paradigms in the Systemic Treatment of Advanced Gallbladder Cancer: Updates in Year 2022

por Hu, Zishuo Ian, Lim, Kian-Huat
Publicado 2022

Stroma-targeting strategies in pancreatic cancer: Past lessons, challenges and prospects

por Polani, Faran, Grierson, Patrick M, Lim, Kian-Huat
Publicado 2021

Oncogenic KRAS-Induced Feedback Inflammatory Signaling in Pancreatic Cancer: An Overview and New Therapeutic Opportunities

por Bansod, Sapana, Dodhiawala, Paarth B., Lim, Kian-Huat
Publicado 2021

Pancreatic cancer survival analysis defines a signature that predicts outcome

por Raman, Pichai, Maddipati, Ravikanth, Lim, Kian Huat, Tozeren, Aydin
Publicado 2018

Deciphering the Role of Innate Immune NF-ĸB Pathway in Pancreatic Cancer

por Khurana, Namrata, Dodhiawala, Paarth B., Bulle, Ashenafi, Lim, Kian-Huat
Publicado 2020

Combined Systemic and Hepatic Artery Infusion Pump Chemo-Therapy as a Liver-Directed Therapy for Colorectal Liver Metastasis-Review of Literature and Case Discussion

por Chaudhry, Salman, Fields, Ryan C., Grierson, Patrick M., Lim, Kian-Huat
Publicado 2021

Distinct clinical and magnetic resonance features of metastatic hepatocellular carcinoma treated with pembrolizumab: A case report of late response after pseudoprogression

por Grierson, Patrick, Crites, Danielle, Ruzinova, Marianna B., Yano, Motoyo, Lim, Kian‐Huat
Publicado 2017

Phospho-Ser(784)-VCP Drives Resistance of Pancreatic Ductal Adenocarcinoma to Genotoxic Chemotherapies and Predicts the Chemo-Sensitizing Effect of VCP Inhibitor

por Wang, Faliang, Vij, Kiran, Li, Lin, Dodhiawala, Paarth, Lim, Kian-Huat, Shao, Jieya
Publicado 2021

RalA and RalBP1 regulate mitochondrial fission at mitosis

por Kashatus, David F., Lim, Kian-Huat, Brady, Donita C., Pershing, Nicole L.K., Cox, Adrienne D., Counter, Christopher M.
Publicado 2011

RNA structure replaces the need for U2AF2 in splicing

por Lin, Chien-Ling, Taggart, Allison J., Lim, Kian Huat, Cygan, Kamil J., Ferraris, Luciana, Creton, Robbert, Huang, Yen-Tsung, Fairbrother, William G.
Publicado 2016

Phase Ib Study of Ulixertinib Plus Gemcitabine and Nab-Paclitaxel in Patients with Metastatic Pancreatic Adenocarcinoma

por Grierson, Patrick M, Tan, Benjamin, Pedersen, Katrina S, Park, Haeseong, Suresh, Rama, Amin, Manik A, Trikalinos, Nikolaos A, Knoerzer, Deborah, Kreider, Brent, Reddy, Anupama, Liu, Jingxia, Der, Channing J, Wang-Gillam, Andrea, Lim, Kian-Huat
Publicado 2022

Antisense oligonucleotide modulation of non-productive alternative splicing upregulates gene expression

por Lim, Kian Huat, Han, Zhou, Jeon, Hyun Yong, Kach, Jacob, Jing, Enxuan, Weyn-Vanhentenryck, Sebastien, Downs, Mikaela, Corrionero, Anna, Oh, Raymond, Scharner, Juergen, Venkatesh, Aditya, Ji, Sophina, Liau, Gene, Ticho, Barry, Nash, Huw, Aznarez, Isabel
Publicado 2020

A clinically feasible multiplex proteomic immunoassay as a novel functional diagnostic for pancreatic ductal adenocarcinoma

por Lim, Kian-Huat, Langley, Emma, Gao, Feng, Luo, Jingqin, Li, Lin, Meyer, Gary, Kim, Phillip, Singh, Sharat, Kushnir, Vladamir M., Early, Dayna S., Mullady, Daniel K., Edmundowicz, Steven A., Wani, Sachin, Murad, Faris M., Cao, Dengfeng, Azar, Riad R., Wang-Gillam, Andrea
Publicado 2017

A Preclinical and Phase Ib Study of Palbociclib plus Nab-Paclitaxel in Patients with Metastatic Adenocarcinoma of the Pancreas

por Hidalgo, Manuel, Garcia-Carbonero, Rocio, Lim, Kian-Huat, Messersmith, Wells A., Garrido-Laguna, Ignacio, Borazanci, Erkut, Lowy, Andrew M., Medina Rodriguez, Laura, Laheru, Daniel, Salvador-Barbero, Beatriz, Malumbres, Marcos, Shields, David J., Grossman, Joseph E., Huang, Xin, Tammaro, Meggan, Martini, Jean-François, Yu, Yanke, Kern, Kenneth, Macarulla, Teresa
Publicado 2022

Induction of cancer neoantigens facilitates development of clinically relevant models for the study of pancreatic cancer immunobiology

por Panni, Usman Y., Chen, Michael Y., Zhang, Felicia, Cullinan, Darren R., Li, Lijin, James, C. Alston, Zhang, Xiuli, Rogers, S., Alarcon, A., Baer, John M., Zhang, Daoxiang, Gao, Feng, Miller, Christopher A., Gong, Qingqing, Lim, Kian-Huat, DeNardo, David G., Goedegebuure, S. Peter, Gillanders, William E., Hawkins, William G.
Publicado 2023

Safety, tolerability, and effectiveness of the sodium-glucose cotransporter 2 inhibitor (SGLT2i) dapagliflozin in combination with standard chemotherapy for patients with advanced,...

por Park, Lauren K., Lim, Kian-Huat, Volkman, Jonas, Abdiannia, Mina, Johnston, Hannah, Nigogosyan, Zack, Siegel, Marilyn J., McGill, Janet B., McKee, Alexis M., Salam, Maamoun, Zhang, Rong M., Ma, Da, Popuri, Karteek, Chow, Vincent Tze Yang, Beg, Mirza Faisal, Hawkins, William G., Peterson, Linda R., Ippolito, Joseph E.
Publicado 2023

Stromal and therapy-induced macrophage proliferation promotes PDAC progression and susceptibility to innate immunotherapy

por Zuo, Chong, Baer, John M., Knolhoff, Brett L., Belle, Jad I., Liu, Xiuting, Alarcon De La Lastra, Angela, Fu, Christina, Hogg, Graham D., Kingston, Natalie L., Breden, Marcus A., Dodhiawala, Paarth B., Zhou, Daniel Cui, Lander, Varintra E., James, C. Alston, Ding, Li, Lim, Kian-Huat, Fields, Ryan C., Hawkins, William G., Weber, Jason D., Zhao, Guoyan, DeNardo, David G.
Publicado 2023

High-dimensional deconstruction of pancreatic cancer identifies tumor microenvironmental and developmental stemness features that predict survival

por Storrs, Erik P., Chati, Prathamesh, Usmani, Abul, Sloan, Ian, Krasnick, Bradley A., Babbra, Ramandeep, Harris, Peter K., Sachs, Chloe M., Qaium, Faridi, Chatterjee, Deyali, Wetzel, Chris, Goedegebuure, S. Peter, Hollander, Thomas, Anthony, Hephzibah, Ponce, Jennifer, Khaliq, Ateeq M., Badiyan, Shahed, Kim, Hyun, Denardo, David G., Lang, Gabriel D., Cosgrove, Natalie D., Kushnir, Vladimir M., Early, Dayna S., Masood, Ashiq, Lim, Kian-Huat, Hawkins, William G., Ding, Li, Fields, Ryan C., Das, Koushik K., Chaudhuri, Aadel A.
Publicado 2023

Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidates for targeted treatment

por Sun, Hua, Cao, Song, Mashl, R. Jay, Mo, Chia-Kuei, Zaccaria, Simone, Wendl, Michael C., Davies, Sherri R., Bailey, Matthew H., Primeau, Tina M., Hoog, Jeremy, Mudd, Jacqueline L., Dean, Dennis A., Patidar, Rajesh, Chen, Li, Wyczalkowski, Matthew A., Jayasinghe, Reyka G., Rodrigues, Fernanda Martins, Terekhanova, Nadezhda V., Li, Yize, Lim, Kian-Huat, Wang-Gillam, Andrea, Van Tine, Brian A., Ma, Cynthia X., Aft, Rebecca, Fuh, Katherine C., Schwarz, Julie K., Zevallos, Jose P., Puram, Sidharth V., Dipersio, John F., Davis-Dusenbery, Brandi, Ellis, Matthew J., Lewis, Michael T., Davies, Michael A., Herlyn, Meenhard, Fang, Bingliang, Roth, Jack A., Welm, Alana L., Welm, Bryan E., Meric-Bernstam, Funda, Chen, Feng, Fields, Ryan C., Li, Shunqiang, Govindan, Ramaswamy, Doroshow, James H., Moscow, Jeffrey A., Evrard, Yvonne A., Chuang, Jeffrey H., Raphael, Benjamin J., Ding, Li
Publicado 2021