Directing an artificial zinc finger protein to new targets by fusion to a non-DNA-binding domain

por Lim, Wooi F., Burdach, Jon, Funnell, Alister P.W., Pearson, Richard C.M., Quinlan, Kate G.R., Crossley, Merlin
Publicado 2016

Regions outside the DNA-binding domain are critical for proper in vivo specificity of an archetypal zinc finger transcription factor

por Burdach, Jon, Funnell, Alister P. W., Mak, Ka Sin, Artuz, Crisbel M., Wienert, Beeke, Lim, Wooi F., Tan, Lit Yeen, Pearson, Richard C. M., Crossley, Merlin
Publicado 2014

Differential regulation of the α-globin locus by Krüppel-like factor 3 in erythroid and non-erythroid cells

por Funnell, Alister PW, Vernimmen, Douglas, Lim, Wooi F, Mak, Ka Sin, Wienert, Beeke, Martyn, Gabriella E, Artuz, Crisbel M, Burdach, Jon, Quinlan, Kate GR, Higgs, Douglas R, Whitelaw, Emma, Pearson, Richard CM, Crossley, Merlin
Publicado 2014

Loss of Krüppel-Like Factor 3 (KLF3/BKLF) Leads to Upregulation of the Insulin-Sensitizing Factor Adipolin (FAM132A/CTRP12/C1qdc2)

por Bell-Anderson, Kim S., Funnell, Alister P., Williams, Helen, Mat Jusoh, Hanapi, Scully, Tiffany, Lim, Wooi F., Burdach, Jon G., Mak, Ka Sin, Knights, Alexander J., Hoy, Andrew J., Nicholas, Hannah R., Sainsbury, Amanda, Turner, Nigel, Pearson, Richard C., Crossley, Merlin
Publicado 2013

GAPDH controls extracellular vesicle biogenesis and enhances the therapeutic potential of EV mediated siRNA delivery to the brain

por Dar, Ghulam Hassan, Mendes, Cláudia C., Kuan, Wei-Li, Speciale, Alfina A., Conceição, Mariana, Görgens, André, Uliyakina, Inna, Lobo, Miguel J., Lim, Wooi F., EL Andaloussi, Samir, Mäger, Imre, Roberts, Thomas C., Barker, Roger A., Goberdhan, Deborah C. I., Wilson, Clive, Wood, Matthew J. A.
Publicado 2021

Author Correction: GAPDH controls extracellular vesicle biogenesis and enhances the therapeutic potential of EV mediated siRNA delivery to the brain

por Dar, Ghulam Hassan, Mendes, Cláudia C., Kuan, Wei-Li, Speciale, Alfina A., Conceição, Mariana, Görgens, André, Uliyakina, Inna, Lobo, Miguel J., Lim, Wooi F., EL Andaloussi, Samir, Mäger, Imre, Roberts, Thomas C., Barker, Roger A., Goberdhan, Deborah C. I., Wilson, Clive, Wood, Matthew J. A.
Publicado 2021

An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides

por Baker, Ysobel R., Thorpe, Cameron, Chen, Jinfeng, Poller, Laura M., Cox, Lina, Kumar, Pawan, Lim, Wooi F., Lie, Lillian, McClorey, Graham, Epple, Sven, Singleton, Daniel, McDonough, Michael A., Hardwick, Jack S., Christensen, Kirsten E., Wood, Matthew J. A., Hall, James P., El-Sagheer, Afaf H., Brown, Tom
Publicado 2022

Gene therapy with AR isoform 2 rescues spinal and bulbar muscular atrophy phenotype by modulating AR transcriptional activity

por Lim, Wooi F., Forouhan, Mitra, Roberts, Thomas C., Dabney, Jesse, Ellerington, Ruth, Speciale, Alfina A., Manzano, Raquel, Lieto, Maria, Sangha, Gavinda, Banerjee, Subhashis, Conceição, Mariana, Cravo, Lara, Biscans, Annabelle, Roux, Loïc, Pourshafie, Naemeh, Grunseich, Christopher, Duguez, Stephanie, Khvorova, Anastasia, Pennuto, Maria, Cortes, Constanza J., La Spada, Albert R., Fischbeck, Kenneth H., Wood, Matthew J.A., Rinaldi, Carlo
Publicado 2021