Ubiquitin-like Protein Conjugation: Structures, Chemistry, and Mechanism

por Cappadocia, Laurent, Lima, Christopher D.
Publicado 2017

Capturing a substrate in an activated RING E3/E2-SUMO complex

por Streich, Frederick C., Lima, Christopher D.
Publicado 2016

The Rrp6 C-terminal domain binds RNA and activates the nuclear RNA exosome

por Wasmuth, Elizabeth V., Lima, Christopher D.
Publicado 2017

Targeting RNA for processing or destruction by the eukaryotic RNA exosome and its cofactors

por Zinder, John C., Lima, Christopher D.
Publicado 2017

Structural basis for MTR4–ZCCHC8 interactions that stimulate the MTR4 helicase in the nuclear exosome-targeting complex

por Puno, M. Rhyan, Lima, Christopher D.
Publicado 2018

Methods to assess helicase and translocation activities of human nuclear RNA exosome and RNA adaptor complexes

por Puno, M. Rhyan, Lima, Christopher D.
Publicado 2022

Structural basis for catalytic activation by the human ZNF451 SUMO E3 ligase

por Cappadocia, Laurent, Pichler, Andrea, Lima, Christopher D.
Publicado 2015

DNA asymmetry promotes SUMO modification of the single‐stranded DNA‐binding protein RPA

por Cappadocia, Laurent, Kochańczyk, Tomasz, Lima, Christopher D
Publicado 2021

Determinants of Small Ubiquitin-like Modifier 1 (SUMO1) Protein Specificity, E3 Ligase, and SUMO-RanGAP1 Binding Activities of Nucleoporin RanBP2

por Gareau, Jaclyn R., Reverter, David, Lima, Christopher D.
Publicado 2012

Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2

por Armstrong, Anthony A., Mohideen, Firaz, Lima, Christopher D.
Publicado 2012

Structure of an Rrp6-RNA exosome complex bound to polyA RNA

por Wasmuth, Elizabeth V., Januszyk, Kurt, Lima, Christopher D.
Publicado 2014

SUMO enhances unfolding of SUMO–polyubiquitin-modified substrates by the Ufd1/Npl4/Cdc48 complex

por Lee, Hyein G., Lemmon, Abigail A., Lima, Christopher D.
Publicado 2022

Crystal structure of the Schizosaccharomyces pombe U7BR E2-binding region in complex with Ubc7

por Hann, Zachary S., Metzger, Meredith B., Weissman, Allan M., Lima, Christopher D.
Publicado 2019

Genetic and structural analysis of the essential fission yeast RNA polymerase II CTD phosphatase Fcp1

por Schwer, Beate, Ghosh, Agnidipta, Sanchez, Ana M., Lima, Christopher D., Shuman, Stewart
Publicado 2015

Active site remodeling accompanies thioester bond formation in the SUMO E1

por Olsen, Shaun K., Capili, Allan D., Lu, Xuequan, Tan, Derek S., Lima, Christopher D.
Publicado 2010

How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes

por Doamekpor, Selom K., Sanchez, Ana M., Schwer, Beate, Shuman, Stewart, Lima, Christopher D.
Publicado 2014

Fission yeast RNA triphosphatase reads an Spt5 CTD code

por Doamekpor, Selom K., Schwer, Beate, Sanchez, Ana M., Shuman, Stewart, Lima, Christopher D.
Publicado 2015

Structure and reconstitution of yeast Mpp6-nuclear exosome complexes reveals that Mpp6 stimulates RNA decay and recruits the Mtr4 helicase

por Wasmuth, Elizabeth V, Zinder, John C, Zattas, Dimitrios, Das, Mom, Lima, Christopher D
Publicado 2017

A molecular basis for phosphorylation-dependent SUMO conjugation by the E2 Ubc9

por Mohideen, Firaz, Capili, Allan D., Bilimoria, Parizad M., Yamada, Tomoko, Bonni, Azad, Lima, Christopher D.
Publicado 2009

Substrate discrimination and quality control require each catalytic activity of TRAMP and the nuclear RNA exosome

por Das, Mom, Zattas, Dimitrios, Zinder, John C., Wasmuth, Elizabeth V., Henri, Julien, Lima, Christopher D.
Publicado 2021