Proton pump inhibitors: from CYP2C19 pharmacogenetics to precision medicine

por El Rouby, Nihal, Lima, John J., Johnson, Julie A.
Publicado 2018

Predicting Inhaled Corticosteroid Response in Asthma with Two Associated SNPs

por McGeachie, Michael J., Wu, Ann C., Chang, Hsun-Hsien, Lima, John J., Peters, Stephen P., Tantisira, Kelan G.
Publicado 2012

Genome-Wide Association Study Identifies Novel Pharmacogenomic Loci For Therapeutic Response to Montelukast in Asthma

por Dahlin, Amber, Litonjua, Augusto, Lima, John J., Tamari, Mayumi, Kubo, Michiaki, Irvin, Charles G., Peters, Stephen P., Tantisira, Kelan G.
Publicado 2015

Associations between serum 25(OH)D concentrations and prevalent asthma among children living in communities with differing levels of urbanization: a cross-sectional study

por Pollard, Suzanne L., Lima, John J., Romero, Karina, Tarazona-Meza, Carla, Mougey, Edward, Tomaino, Katherine, Malpartida-Guzmán, Gary, Hansel, Nadia N., Checkley, William
Publicado 2017

Low cigarette smoking prevalence in peri-urban Peru: results from a population-based study of tobacco use by self-report and urine cotinine

por Morgan, Brooks W., Leifheit, Kathryn M., Romero, Karina M., Gilman, Robert H., Bernabe-Ortiz, Antonio, Miranda, J. Jaime, Feldman, Harold I., Lima, John J., Checkley, William
Publicado 2017

Genotype tailored treatment of mild symptomatic acid reflux in children with uncontrolled asthma (GenARA): Rationale and methods

por Tang, Monica, Blake, Kathryn V., Lima, John J., Mougey, Edward B., Franciosi, James, Schmidt, Stephan, Hossain, Md Jobayer, Cobbaert, Marjan, Fischer, Bernard M., Lang, Jason E.
Publicado 2019

The phosphatidylinositide 3-kinase (PI3K) signaling pathway is a determinant of zileuton response in adults with asthma

por Dahlin, Amber, Qiu, Weiliang, Litonjua, Augusto A., Lima, John J., Tamari, Mayumi, Kubo, Michiaki, Irvin, Charles G., Peters, Stephen P., Wu, Ann C., Weiss, Scott T., Tantisira, Kelan G.
Publicado 2018

Novel Implementation of Genotype‐Guided Proton Pump Inhibitor Medication Therapy in Children: A Pilot, Randomized, Multisite Pragmatic Trial

por Cicali, Emily J., Blake, Kathryn, Gong, Yan, Mougey, Edward B., Al‐Atrash, Hadeel, Chambers, Nancy, Denham, Jolanda, Evans, Jonathan, George, Donald E., Gomez, Roberto, Palomo, Pablo, Taufiq, Salik, Johnson, Julie A., Lima, John J., Franciosi, James P.
Publicado 2018

A polymorphism in the thyroid hormone receptor gene is associated with bronchodilator response in asthmatics

por Duan, Qing Ling, Du, Rose, Lasky-Su, Jessica, Klanderman, Barbara J., Partch, Amanda B., Peters, Stephen P., Irvin, Charles G., Hanrahan, John P., Lima, John J., Blake, Kathryn V., Liggett, Stephen B., Litonjua, Augusto A., Tantisira, Kelan G.
Publicado 2012

CYP2C19 and STAT6 Variants Influence the Outcome of Proton Pump Inhibitor Therapy in Pediatric Eosinophilic Esophagitis

por Mougey, Edward B., Williams, Andre, Coyne, Ashlan J. Kunz, Gutiérrez-Junquera, Carolina, Fernández-Fernández, Sonia, Cilleruelo, Maria Luz, Rayo, Ana, Echeverría, Luis, Román, Enriqueta, González Lois, Carmen, Chao, Montserrat, Al-Atrash, Hadeel, Lima, John J., Franciosi, James P.
Publicado 2019

A genome-wide association study of bronchodilator response in asthmatics

por Duan, Qing Ling, Lasky-Su, Jessica, Himes, Blanca E., Qiu, Weiliang, Litonjua, Augusto A., Damask, Amy, Lazarus, Ross, Klanderman, Barbara, Irvin, Charles G., Peters, Stephen P., Hanrahan, John P., Lima, John J., Martinez, Fernando D., Mauger, David, Chinchilli, Vernon M., Soto-Quiros, Manuel, Avila, Lydiana, Celedón, Juan C., Lange, Christoph, Weiss, Scott T., Tantisira, Kelan G.
Publicado 2013

Asthma in the elderly: Current understanding and future research needs—a report of a National Institute on Aging (NIA) workshop

por Hanania, Nicola A., King, Monroe J., Braman, Sidney S., Saltoun, Carol, Wise, Robert A., Enright, Paul, Falsey, Ann R., Mathur, Sameer K., Ramsdell, Joe W., Rogers, Linda, Stempel, David A., Lima, John J., Fish, James E., Wilson, Sandra R., Boyd, Cynthia, Patel, Kushang V., Irvin, Charles G., Yawn, Barbara P., Halm, Ethan A., Wasserman, Stephen I., Sands, Mark F., Ershler, William B., Ledford, Dennis K.
Publicado 2011

Genome-Wide Association Analysis in Asthma Subjects Identifies SPATS2L as a Novel Bronchodilator Response Gene

por Himes, Blanca E., Jiang, Xiaofeng, Hu, Ruoxi, Wu, Ann C., Lasky-Su, Jessica A., Klanderman, Barbara J., Ziniti, John, Senter-Sylvia, Jody, Lima, John J., Irvin, Charles G., Peters, Stephen P., Meyers, Deborah A., Bleecker, Eugene R., Kubo, Michiaki, Tamari, Mayumi, Nakamura, Yusuke, Szefler, Stanley J., Lemanske, Robert F., Zeiger, Robert S., Strunk, Robert C., Martinez, Fernando D., Hanrahan, John P., Koppelman, Gerard H., Postma, Dirkje S., Nieuwenhuis, Maartje A. E., Vonk, Judith M., Panettieri, Reynold A., Markezich, Amy, Israel, Elliot, Carey, Vincent J., Tantisira, Kelan G., Litonjua, Augusto A., Lu, Quan, Weiss, Scott T.
Publicado 2012

Integration of Mouse and Human Genome-Wide Association Data Identifies KCNIP4 as an Asthma Gene

por Himes, Blanca E., Sheppard, Keith, Berndt, Annerose, Leme, Adriana S., Myers, Rachel A., Gignoux, Christopher R., Levin, Albert M., Gauderman, W. James, Yang, James J., Mathias, Rasika A., Romieu, Isabelle, Torgerson, Dara G., Roth, Lindsey A., Huntsman, Scott, Eng, Celeste, Klanderman, Barbara, Ziniti, John, Senter-Sylvia, Jody, Szefler, Stanley J., Lemanske, Robert F., Zeiger, Robert S., Strunk, Robert C., Martinez, Fernando D., Boushey, Homer, Chinchilli, Vernon M., Israel, Elliot, Mauger, David, Koppelman, Gerard H., Postma, Dirkje S., Nieuwenhuis, Maartje A. E., Vonk, Judith M., Lima, John J., Irvin, Charles G., Peters, Stephen P., Kubo, Michiaki, Tamari, Mayumi, Nakamura, Yusuke, Litonjua, Augusto A., Tantisira, Kelan G., Raby, Benjamin A., Bleecker, Eugene R., Meyers, Deborah A., London, Stephanie J., Barnes, Kathleen C., Gilliland, Frank D., Williams, L. Keoki, Burchard, Esteban G., Nicolae, Dan L., Ober, Carole, DeMeo, Dawn L., Silverman, Edwin K., Paigen, Beverly, Churchill, Gary, Shapiro, Steve D., Weiss, Scott T.
Publicado 2013