Single-cell massively-parallel multiplexed microbial sequencing (M3-seq) identifies rare bacterial populations and profiles phage infection

por Wang, Bruce, Lin, Aaron E., Yuan, Jiayi, Novak, Katherine E., Koch, Matthias D., Wingreen, Ned S., Adamson, Britt, Gitai, Zemer
Publicado 2023

Innovative Technologies for Advancement of WHO Risk Group 4 Pathogens Research

por Logue, James, Solomon, Jeffrey, Niemeyer, Brian F., Benam, Kambez H., Lin, Aaron E., Bjornson, Zach, Jiang, Sizun, McIlwain, David R., Nolan, Garry P., Palacios, Gustavo, Kuhn, Jens H.
Publicado 2019

Evaluation of the Potential Impact of Ebola Virus Genomic Drift on the Efficacy of Sequence-Based Candidate Therapeutics

por Kugelman, Jeffrey R., Sanchez-Lockhart, Mariano, Andersen, Kristian G., Gire, Stephen, Park, Daniel J., Sealfon, Rachel, Lin, Aaron E., Wohl, Shirlee, Sabeti, Pardis C., Kuhn, Jens H., Palacios, Gustavo F.
Publicado 2015

In vivo Ebola virus infection leads to a strong innate response in circulating immune cells

por Caballero, Ignacio S., Honko, Anna N., Gire, Stephen K., Winnicki, Sarah M., Melé, Marta, Gerhardinger, Chiara, Lin, Aaron E., Rinn, John L., Sabeti, Pardis C., Hensley, Lisa E., Connor, John H.
Publicado 2016

Single-cell profiling of lncRNA expression during Ebola virus infection in rhesus macaques

por Santus, Luisa, Sopena-Rios, Maria, García-Pérez, Raquel, Lin, Aaron E., Adams, Gordon C., Barnes, Kayla G., Siddle, Katherine J., Wohl, Shirlee, Reverter, Ferran, Rinn, John L., Bennett, Richard S., Hensley, Lisa E., Sabeti, Pardis C., Melé, Marta
Publicado 2023

Reporter Assays for Ebola Virus Nucleoprotein Oligomerization, Virion-Like Particle Budding, and Minigenome Activity Reveal the Importance of Nucleoprotein Amino Acid Position 111

por Lin, Aaron E., Diehl, William E., Cai, Yingyun, Finch, Courtney L., Akusobi, Chidiebere, Kirchdoerfer, Robert N., Bollinger, Laura, Schaffner, Stephen F., Brown, Elizabeth A., Saphire, Erica Ollmann, Andersen, Kristian G., Kuhn, Jens H., Luban, Jeremy, Sabeti, Pardis C.
Publicado 2020

Ebola Virus Glycoprotein with Increased Infectivity Dominated the 2013–2016 Epidemic

por Diehl, William E., Lin, Aaron E., Grubaugh, Nathan D., Carvalho, Luiz Max, Kim, Kyusik, Kyawe, Pyae Phyo, McCauley, Sean M., Donnard, Elisa, Kucukural, Alper, McDonel, Patrick, Schaffner, Stephen F., Garber, Manuel, Rambaut, Andrew, Andersen, Kristian G., Sabeti, Pardis C., Luban, Jeremy
Publicado 2016

SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses

por Banerjee, Abhik K., Blanco, Mario R., Bruce, Emily A., Honson, Drew D., Chen, Linlin M., Chow, Amy, Bhat, Prashant, Ollikainen, Noah, Quinodoz, Sofia A., Loney, Colin, Thai, Jasmine, Miller, Zachary D., Lin, Aaron E., Schmidt, Madaline M., Stewart, Douglas G., Goldfarb, Daniel, De Lorenzo, Giuditta, Rihn, Suzannah J., Voorhees, Rebecca M., Botten, Jason W., Majumdar, Devdoot, Guttman, Mitchell
Publicado 2020

Single-Cell Profiling of Ebola Virus Disease In Vivo Reveals Viral and Host Dynamics

por Kotliar, Dylan, Lin, Aaron E., Logue, James, Hughes, Travis K., Khoury, Nadine M., Raju, Siddharth S., Wadsworth, Marc H., Chen, Han, Kurtz, Jonathan R., Dighero-Kemp, Bonnie, Bjornson, Zach B., Mukherjee, Nilanjan, Sellers, Brian A., Tran, Nancy, Bauer, Matthew R., Adams, Gordon C., Adams, Ricky, Rinn, John L., Melé, Marta, Schaffner, Stephen F., Nolan, Garry P., Barnes, Kayla G., Hensley, Lisa E., McIlwain, David R., Shalek, Alex K., Sabeti, Pardis C., Bennett, Richard S.
Publicado 2020

Field validation of recombinant antigen immunoassays for diagnosis of Lassa fever

por Boisen, Matthew L., Hartnett, Jessica N., Shaffer, Jeffrey G., Goba, Augustine, Momoh, Mambu, Sandi, John Demby, Fullah, Mohamed, Nelson, Diana K. S., Bush, Duane J., Rowland, Megan M., Heinrich, Megan L., Koval, Anatoliy P., Cross, Robert W., Barnes, Kayla G., Lachenauer, Anna E., Lin, Aaron E., Nekoui, Mahan, Kotliar, Dylan, Winnicki, Sarah M., Siddle, Katherine J., Gbakie, Michael, Fonnie, Mbalu, Koroma, Veronica J., Kanneh, Lansana, Kulakosky, Peter C., Hastie, Kathryn M., Wilson, Russell B., Andersen, Kristian G., Folarin, Onikepe O., Happi, Christian T., Sabeti, Pardis C., Geisbert, Thomas W., Saphire, Erica Ollmann, Khan, S. Humarr, Grant, Donald S., Schieffelin, John S., Branco, Luis M., Garry, Robert F.
Publicado 2018

Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time

por Barnes, Kayla G., Lachenauer, Anna E., Nitido, Adam, Siddiqui, Sameed, Gross, Robin, Beitzel, Brett, Siddle, Katherine J., Freije, Catherine A., Dighero-Kemp, Bonnie, Mehta, Samar B., Carter, Amber, Uwanibe, Jessica, Ajogbasile, Fehintola, Olumade, Testimony, Odia, Ikponmwosa, Sandi, John Demby, Momoh, Mambu, Metsky, Hayden C., Boehm, Chloe K., Lin, Aaron E., Kemball, Molly, Park, Daniel J., Branco, Luis, Boisen, Matt, Sullivan, Brian, Amare, Mihret F., Tiamiyu, Abdulwasiu B., Parker, Zahra F., Iroezindu, Michael, Grant, Donald S., Modjarrad, Kayvon, Myhrvold, Cameron, Garry, Robert F., Palacios, Gustavo, Hensley, Lisa E., Schaffner, Stephen F., Happi, Christian T., Colubri, Andres, Sabeti, Pardis C.
Publicado 2020

Capturing sequence diversity in metagenomes with comprehensive and scalable probe design

por Metsky, Hayden C., Siddle, Katherine J., Gladden-Young, Adrianne, Qu, James, Yang, David K., Brehio, Patrick, Goldfarb, Andrew, Piantadosi, Anne, Wohl, Shirlee, Carter, Amber, Lin, Aaron E., Barnes, Kayla G., Tully, Damien C., Corleis, Bjӧrn, Hennigan, Scott, Barbosa-Lima, Giselle, Vieira, Yasmine R., Paul, Lauren M., Tan, Amanda L., Garcia, Kimberly F., Parham, Leda A., Odia, Ikponmwosa, Eromon, Philomena, Folarin, Onikepe A., Goba, Augustine, Simon-Lorière, Etienne, Hensley, Lisa, Balmaseda, Angel, Harris, Eva, Kwon, Douglas S., Allen, Todd M., Runstadler, Jonathan A., Smole, Sandra, Bozza, Fernando A., Souza, Thiago M. L., Isern, Sharon, Michael, Scott F., Lorenzana, Ivette, Gehrke, Lee, Bosch, Irene, Ebel, Gregory, Grant, Donald S., Happi, Christian T., Park, Daniel J., Gnirke, Andreas, Sabeti, Pardis C., Matranga, Christian B.
Publicado 2019

Phylogenetic analysis of SARS-CoV-2 in the Boston area highlights the role of recurrent importation and superspreading events.

por Lemieux, Jacob E., Siddle, Katherine J., Shaw, Bennett M., Loreth, Christine, Schaffner, Stephen F., Gladden-Young, Adrianne, Adams, Gordon, Fink, Timelia, Tomkins-Tinch, Christopher H., Krasilnikova, Lydia A., DeRuff, Katherine C., Rudy, Melissa, Bauer, Matthew R., Lagerborg, Kim A., Normandin, Erica, Chapman, Sinead B., Reilly, Steven K., Anahtar, Melis N., Lin, Aaron E., Carter, Amber, Myhrvold, Cameron, Kemball, Molly E., Chaluvadi, Sushma, Cusick, Caroline, Flowers, Katelyn, Neumann, Anna, Cerrato, Felecia, Farhat, Maha, Slater, Damien, Harris, Jason B., Branda, John, Hooper, David, Gaeta, Jessie M., Baggett, Travis P., O’Connell, James, Gnirke, Andreas, Lieberman, Tami D., Philippakis, Anthony, Burns, Meagan, Brown, Catherine M., Luban, Jeremy, Ryan, Edward T., Turbett, Sarah E., LaRocque, Regina C., Hanage, William P., Gallagher, Glen R., Madoff, Lawrence C., Smole, Sandra, Pierce, Virginia M., Rosenberg, Eric, Sabeti, Pardis C., Park, Daniel J., Maclnnis, Bronwyn L.
Publicado 2020

Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events

por Lemieux, Jacob E., Siddle, Katherine J., Shaw, Bennett M., Loreth, Christine, Schaffner, Stephen F., Gladden-Young, Adrianne, Adams, Gordon, Fink, Timelia, Tomkins-Tinch, Christopher H., Krasilnikova, Lydia A., DeRuff, Katherine C., Rudy, Melissa, Bauer, Matthew R., Lagerborg, Kim A., Normandin, Erica, Chapman, Sinéad B., Reilly, Steven K., Anahtar, Melis N., Lin, Aaron E., Carter, Amber, Myhrvold, Cameron, Kemball, Molly E., Chaluvadi, Sushma, Cusick, Caroline, Flowers, Katelyn, Neumann, Anna, Cerrato, Felecia, Farhat, Maha, Slater, Damien, Harris, Jason B., Branda, John A., Hooper, David, Gaeta, Jessie M., Baggett, Travis P., O’Connell, James, Gnirke, Andreas, Lieberman, Tami D., Philippakis, Anthony, Burns, Meagan, Brown, Catherine M., Luban, Jeremy, Ryan, Edward T., Turbett, Sarah E., LaRocque, Regina C., Hanage, William P., Gallagher, Glen R., Madoff, Lawrence C., Smole, Sandra, Pierce, Virginia M., Rosenberg, Eric, Sabeti, Pardis C., Park, Daniel J., MacInnis, Bronwyn L.
Publicado 2020

Ebola Virus Epidemiology, Transmission, and Evolution during Seven Months in Sierra Leone

por Park, Daniel J., Dudas, Gytis, Wohl, Shirlee, Goba, Augustine, Whitmer, Shannon L.M., Andersen, Kristian G., Sealfon, Rachel S., Ladner, Jason T., Kugelman, Jeffrey R., Matranga, Christian B., Winnicki, Sarah M., Qu, James, Gire, Stephen K., Gladden-Young, Adrianne, Jalloh, Simbirie, Nosamiefan, Dolo, Yozwiak, Nathan L., Moses, Lina M., Jiang, Pan-Pan, Lin, Aaron E., Schaffner, Stephen F., Bird, Brian, Towner, Jonathan, Mamoh, Mambu, Gbakie, Michael, Kanneh, Lansana, Kargbo, David, Massally, James L.B., Kamara, Fatima K., Konuwa, Edwin, Sellu, Josephine, Jalloh, Abdul A., Mustapha, Ibrahim, Foday, Momoh, Yillah, Mohamed, Erickson, Bobbie R., Sealy, Tara, Blau, Dianna, Paddock, Christopher, Brault, Aaron, Amman, Brian, Basile, Jane, Bearden, Scott, Belser, Jessica, Bergeron, Eric, Campbell, Shelley, Chakrabarti, Ayan, Dodd, Kimberly, Flint, Mike, Gibbons, Aridth, Goodman, Christin, Klena, John, McMullan, Laura, Morgan, Laura, Russell, Brandy, Salzer, Johanna, Sanchez, Angela, Wang, David, Jungreis, Irwin, Tomkins-Tinch, Christopher, Kislyuk, Andrey, Lin, Michael F., Chapman, Sinead, MacInnis, Bronwyn, Matthews, Ashley, Bochicchio, James, Hensley, Lisa E., Kuhn, Jens H., Nusbaum, Chad, Schieffelin, John S., Birren, Bruce W., Forget, Marc, Nichol, Stuart T., Palacios, Gustavo F., Ndiaye, Daouda, Happi, Christian, Gevao, Sahr M., Vandi, Mohamed A., Kargbo, Brima, Holmes, Edward C., Bedford, Trevor, Gnirke, Andreas, Ströher, Ute, Rambaut, Andrew, Garry, Robert F., Sabeti, Pardis C.
Publicado 2015