Respiratory Syncytial Virus (RSV) Neutralizing Antibodies at Birth Predict Protection from RSV Illness in Infants in the First 3 Months of Life

por Buchwald, Andrea G, Graham, Barney S, Traore, Awa, Haidara, Fadima Cheick, Chen, Man, Morabito, Kaitlyn, Lin, Bob C, Sow, Samba O, Levine, Myron M, Pasetti, Marcela F, Tapia, Milagritos D
Publicado 2020

Extended antibody-framework-to-antigen distance observed exclusively with broad HIV-1-neutralizing antibodies recognizing glycan-dense surfaces

por Lee, Myungjin, Changela, Anita, Gorman, Jason, Rawi, Reda, Bylund, Tatsiana, Chao, Cara W., Lin, Bob C., Louder, Mark K., Olia, Adam S., Zhang, Baoshan, Doria-Rose, Nicole A., Zolla-Pazner, Susan, Shapiro, Lawrence, Chuang, Gwo-Yu, Kwong, Peter D.
Publicado 2021

Rapid selection of HIV envelopes that bind to neutralizing antibody B cell lineage members with functional improbable mutations

por Swanson, Olivia, Rhodes, Brianna, Wang, Avivah, Xia, Shi-Mao, Parks, Robert, Chen, Haiyan, Sanzone, Aja, Cooper, Melissa, Louder, Mark K., Lin, Bob C., Doria-Rose, Nicole A., Bonsignori, Mattia, Saunders, Kevin O., Wiehe, Kevin, Haynes, Barton F., Azoitei, Mihai L.
Publicado 2021

Improved HIV-1 neutralization breadth and potency of V2-apex antibodies by in silico design

por Holt, Graham T., Gorman, Jason, Wang, Siyu, Lowegard, Anna U., Zhang, Baoshan, Liu, Tracy, Lin, Bob C., Louder, Mark K., Frenkel, Marcel S., McKee, Krisha, O’Dell, Sijy, Rawi, Reda, Shen, Chen-Hsiang, Doria-Rose, Nicole A., Kwong, Peter D., Donald, Bruce R.
Publicado 2023

A matrix of structure-based designs yields improved VRC01-class antibodies for HIV-1 therapy and prevention

por Kwon, Young D., Asokan, Mangaiarkarasi, Gorman, Jason, Zhang, Baoshan, Liu, Qingbo, Louder, Mark K., Lin, Bob C., McKee, Krisha, Pegu, Amarendra, Verardi, Raffaello, Yang, Eun Sung, Program, VRC Production, Carlton, Kevin, Doria-Rose, Nicole A., Lusso, Paolo, Mascola, John R., Kwong, Peter D.
Publicado 2021

Deep Phenotyping of Neurologic Postacute Sequelae of SARS-CoV-2 Infection

por Mina, Yair, Enose-Akahata, Yoshimi, Hammoud, Dima A., Videckis, Anthony J., Narpala, Sandeep R., O'Connell, Sarah E., Carroll, Robin, Lin, Bob C., McMahan, Cynthia Chen, Nair, Govind, Reoma, Lauren B., McDermott, Adrian B., Walitt, Brian, Jacobson, Steven, Goldstein, David S., Smith, Bryan R., Nath, Avindra
Publicado 2023

Improved pharmacokinetics of HIV-neutralizing VRC01-class antibodies achieved by reduction of net positive charge on variable domain

por Kwon, Young D., Pegu, Amarendra, Yang, Eun Sung, Zhang, Baoshan, Bender, Michael F., Asokan, Mangaiarkarasi, Liu, Qingbo, McKee, Krisha, Lin, Bob C., Liu, Tracy, Louder, Mark K., Rawi, Reda, Reveiz, Mateo, Schaub, Andrew J., Shen, Chen-Hsiang, Doria-Rose, Nicole A., Lusso, Paolo, Mascola, John R., Kwong, Peter D.
Publicado 2023

Removal of variable domain N-linked glycosylation as a means to improve the homogeneity of HIV-1 broadly neutralizing antibodies

por Chuang, Gwo-Yu, Asokan, Mangaiarkarasi, Ivleva, Vera B., Pegu, Amarendra, Yang, Eun Sung, Zhang, Baoshan, Chaudhuri, Rajoshi, Geng, Hui, Lin, Bob C., Louder, Mark K., McKee, Krisha, O’Dell, Sijy, Wang, Hairong, Zhou, Tongqing, Doria-Rose, Nicole A., Kueltzo, Lisa A., Lei, Q. Paula, Mascola, John R., Kwong, Peter D.
Publicado 2020

Human CD4-Binding Site Antibody Elicited by Polyvalent DNA Prime-Protein Boost Vaccine Neutralizes Cross-Clade Tier-2-HIV Strains

por Wang, Shixia, Chan, Kun-Wei, Wei, Danlan, Ma, Xiuwen, Liu, Shuying, Hu, Guangnan, Park, Saeyoung, Pan, Ruimin, Gu, Ying, Nazzari, Alexandra F., Olia, Adam S., Xu, Kai, Lin, Bob C., Louder, Mark K., Doria-Rose, Nicole A., Montefiori, David, Seaman, Michael S., Zhou, Tongqing, Kwong, Peter D., Arthos, James, Kong, Xiang-Peng, Lu, Shan
Publicado 2023

Tyrosine O-sulfation proteoforms affect HIV-1 monoclonal antibody potency

por Cai, Cindy X., Doria-Rose, Nicole A., Schneck, Nicole A., Ivleva, Vera B., Tippett, Brad, Shadrick, William R., O’Connell, Sarah, Cooper, Jonathan W., Schneiderman, Zachary, Zhang, Baoshan, Gowetski, Daniel B., Blackstock, Daniel, Demirji, Jacob, Lin, Bob C., Gorman, Jason, Liu, Tracy, Li, Yile, McDermott, Adrian B., Kwong, Peter D., Carlton, Kevin, Gall, Jason G., Lei, Q. Paula
Publicado 2022

Recent SARS-CoV-2 infection abrogates antibody and B-cell responses to booster vaccination

por Buckner, Clarisa M., Kardava, Lela, Merhebi, Omar El, Narpala, Sandeep R., Serebryannyy, Leonid, Lin, Bob C., Wang, Wei, Zhang, Xiaozhen, de Assis, Felipe Lopes, Kelly, Sophie E.M., Teng, I-Ting, McCormack, Genevieve E., Praiss, Lauren H., Seamon, Catherine A., Rai, M. Ali, Kalish, Heather, Kwong, Peter D., Proschan, Michael A., McDermott, Adrian B., Fauci, Anthony S., Chun, Tae-Wook, Moir, Susan
Publicado 2022

Interval between prior SARS-CoV-2 infection and booster vaccination impacts magnitude and quality of antibody and B cell responses

por Buckner, Clarisa M., Kardava, Lela, El Merhebi, Omar, Narpala, Sandeep R., Serebryannyy, Leonid, Lin, Bob C., Wang, Wei, Zhang, Xiaozhen, Lopes de Assis, Felipe, Kelly, Sophie E.M., Teng, I-Ting, McCormack, Genevieve E., Praiss, Lauren H., Seamon, Catherine A., Rai, M. Ali, Kalish, Heather, Kwong, Peter D., Proschan, Michael A., McDermott, Adrian B., Fauci, Anthony S., Chun, Tae-Wook, Moir, Susan
Publicado 2022

Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site

por Banach, Bailey B., Pletnev, Sergei, Olia, Adam S., Xu, Kai, Zhang, Baoshan, Rawi, Reda, Bylund, Tatsiana, Doria-Rose, Nicole A., Nguyen, Thuy Duong, Fahad, Ahmed S., Lee, Myungjin, Lin, Bob C., Liu, Tracy, Louder, Mark K., Madan, Bharat, McKee, Krisha, O’Dell, Sijy, Sastry, Mallika, Schön, Arne, Bui, Natalie, Shen, Chen-Hsiang, Wolfe, Jacy R., Chuang, Gwo-Yu, Mascola, John R., Kwong, Peter D., DeKosky, Brandon J.
Publicado 2023

Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies

por Cottrell, Christopher A., Manne, Kartik, Kong, Rui, Wang, Shuishu, Zhou, Tongqing, Chuang, Gwo-Yu, Edwards, Robert J., Henderson, Rory, Janowska, Katarzyna, Kopp, Megan, Lin, Bob C., Louder, Mark K., Olia, Adam S., Rawi, Reda, Shen, Chen-Hsiang, Taft, Justin D., Torres, Jonathan L., Wu, Nelson R., Zhang, Baoshan, Doria-Rose, Nicole A., Cohen, Myron S., Haynes, Barton F., Shapiro, Lawrence, Ward, Andrew B., Acharya, Priyamvada, Mascola, John R., Kwong, Peter D.
Publicado 2021

Engineering of HIV-1 neutralizing antibody CAP256V2LS for manufacturability and improved half life

por Zhang, Baoshan, Gollapudi, Deepika, Gorman, Jason, O’Dell, Sijy, Damron, Leland F., McKee, Krisha, Asokan, Mangaiarkarasi, Yang, Eun Sung, Pegu, Amarendra, Lin, Bob C., Chao, Cara W., Chen, Xuejun, Gama, Lucio, Ivleva, Vera B., Law, William H., Liu, Cuiping, Louder, Mark K., Schmidt, Stephen D., Shen, Chen-Hsiang, Shi, Wei, Stein, Judith A., Seaman, Michael S., McDermott, Adrian B., Carlton, Kevin, Mascola, John R., Kwong, Peter D., Lei, Q. Paula, Doria-Rose, Nicole A.
Publicado 2022

Antibody Persistence through 6 Months after the Second Dose of mRNA-1273 Vaccine for Covid-19

por Doria-Rose, Nicole, Suthar, Mehul S., Makowski, Mat, O’Connell, Sarah, McDermott, Adrian B., Flach, Britta, Ledgerwood, Julie E., Mascola, John R., Graham, Barney S., Lin, Bob C., O’Dell, Sijy, Schmidt, Stephen D., Widge, Alicia T., Edara, Venkata-Viswanadh, Anderson, Evan J., Lai, Lilin, Floyd, Katharine, Rouphael, Nadine G., Zarnitsyna, Veronika, Roberts, Paul C., Makhene, Mamodikoe, Buchanan, Wendy, Luke, Catherine J., Beigel, John H., Jackson, Lisa A., Neuzil, Kathleen M., Bennett, Hamilton, Leav, Brett, Albert, Jim, Kunwar, Pratap
Publicado 2021

Durability of Responses after SARS-CoV-2 mRNA-1273 Vaccination

por Widge, Alicia T., Rouphael, Nadine G., Jackson, Lisa A., Anderson, Evan J., Roberts, Paul C., Makhene, Mamodikoe, Chappell, James D., Denison, Mark R., Stevens, Laura J., Pruijssers, Andrea J., McDermott, Adrian B., Flach, Britta, Lin, Bob C., Doria-Rose, Nicole A., O’Dell, Sijy, Schmidt, Stephen D., Neuzil, Kathleen M., Bennett, Hamilton, Leav, Brett, Makowski, Mat, Albert, Jim, Cross, Kaitlyn, Edara, Venkata-Viswanadh, Floyd, Katharine, Suthar, Mehul S., Buchanan, Wendy, Luke, Catherine J., Ledgerwood, Julie E., Mascola, John R., Graham, Barney S., Beigel, John H.
Publicado 2020

Stochastic Interventional Vaccine Efficacy and Principal Surrogate Analyses of Antibody Markers as Correlates of Protection against Symptomatic COVID-19 in the COVE mRNA-1273 Trial

por Huang, Ying, Hejazi, Nima S., Blette, Bryan, Carpp, Lindsay N., Benkeser, David, Montefiori, David C., McDermott, Adrian B., Fong, Youyi, Janes, Holly E., Deng, Weiping, Zhou, Honghong, Houchens, Christopher R., Martins, Karen, Jayashankar, Lakshmi, Flach, Britta, Lin, Bob C., O’Connell, Sarah, McDanal, Charlene, Eaton, Amanda, Sarzotti-Kelsoe, Marcella, Lu, Yiwen, Yu, Chenchen, Kenny, Avi, Carone, Marco, Huynh, Chuong, Miller, Jacqueline, El Sahly, Hana M., Baden, Lindsey R., Jackson, Lisa A., Campbell, Thomas B., Clark, Jesse, Andrasik, Michele P., Kublin, James G., Corey, Lawrence, Neuzil, Kathleen M., Pajon, Rolando, Follmann, Dean, Donis, Ruben O., Koup, Richard A., Gilbert, Peter B.
Publicado 2023

Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults

por Anderson, Evan J., Rouphael, Nadine G., Widge, Alicia T., Jackson, Lisa A., Roberts, Paul C., Makhene, Mamodikoe, Chappell, James D., Denison, Mark R., Stevens, Laura J., Pruijssers, Andrea J., McDermott, Adrian B., Flach, Britta, Lin, Bob C., Doria-Rose, Nicole A., O’Dell, Sijy, Schmidt, Stephen D., Corbett, Kizzmekia S., Swanson, Phillip A., Padilla, Marcelino, Neuzil, Kathy M., Bennett, Hamilton, Leav, Brett, Makowski, Mat, Albert, Jim, Cross, Kaitlyn, Edara, Venkata Viswanadh, Floyd, Katharine, Suthar, Mehul S., Martinez, David R., Baric, Ralph, Buchanan, Wendy, Luke, Catherine J., Phadke, Varun K., Rostad, Christina A., Ledgerwood, Julie E., Graham, Barney S., Beigel, John H.
Publicado 2020

Immunogenicity of NVX-CoV2373 heterologous boost against SARS-CoV-2 variants

por Lyke, Kirsten E., Atmar, Robert L., Dominguez Islas, Clara, Posavad, Christine M., Deming, Meagan E., Branche, Angela R., Johnston, Christine, El Sahly, Hana M., Edupuganti, Srilatha, Mulligan, Mark J., Jackson, Lisa A., Rupp, Richard E., Rostad, Christina A., Coler, Rhea N., Bäcker, Martín, Kottkamp, Angelica C., Babu, Tara M., Dobrzynski, David, Martin, Judith M., Brady, Rebecca C., Frenck, Robert W., Rajakumar, Kumaravel, Kotloff, Karen, Rouphael, Nadine, Szydlo, Daniel, PaulChoudhury, Rahul, Archer, Janet I., Crandon, Sonja, Ingersoll, Brian, Eaton, Amanda, Brown, Elizabeth R., McElrath, M. Juliana, Neuzil, Kathleen M., Stephens, David S., Post, Diane J., Lin, Bob C., Serebryannyy, Leonid, Beigel, John H., Montefiori, David C., Roberts, Paul C.
Publicado 2023