Including probe-level uncertainty in model-based gene expression clustering

por Liu, Xuejun, Lin, Kevin K, Andersen, Bogi, Rattray, Magnus
Publicado 2007

A data-informed mean-field approach to mapping of cortical parameter landscapes

por Xiao, Zhuo-Cheng, Lin, Kevin K., Young, Lai-Sang
Publicado 2021

Phase-Amplitude Descriptions of Neural Oscillator Models

por Wedgwood, Kyle CA, Lin, Kevin K, Thul, Ruediger, Coombes, Stephen
Publicado 2013

The influence of multiple firing events on the formation and stability of activity patterns in continuous attractor networks

por Lyttle, David, Weitzenfeld, Alfredo, Fellous, Jean-Marc, Lin, Kevin K
Publicado 2013

Encoding in Balanced Networks: Revisiting Spike Patterns and Chaos in Stimulus-Driven Systems

por Lajoie, Guillaume, Lin, Kevin K., Thivierge, Jean-Philippe, Shea-Brown, Eric
Publicado 2016

Circadian Clock Genes Contribute to the Regulation of Hair Follicle Cycling

por Lin, Kevin K., Kumar, Vivek, Geyfman, Mikhail, Chudova, Darya, Ihler, Alexander T., Smyth, Padhraic, Paus, Ralf, Takahashi, Joseph S., Andersen, Bogi
Publicado 2009

Network analysis of skin tumor progression identifies a rewired genetic architecture affecting inflammation and tumor susceptibility

por Quigley, David A, To, Minh D, Kim, Il Jin, Lin, Kevin K, Albertson, Donna G, Sjolund, Jonas, Pérez-Losada, Jesús, Balmain, Allan
Publicado 2011

Mathematical modeling of the early modeled CA-125 longitudinal kinetics (KELIM-PARP) as a pragmatic indicator of rucaparib efficacy in patients with recurrent ovarian carcinoma in...

por Colomban, Olivier, Swisher, Elizabeth M., Kristeleit, Rebecca, McNeish, Iain, Shapira-Frommer, Ronnie, Goble, Sandra, Lin, Kevin K., Maloney, Lara, Freyer, Gilles, You, Benoit
Publicado 2023

Phase Ib SEASTAR Study: Combining Rucaparib and Sacituzumab Govitecan in Patients With Cancer With or Without Mutations in Homologous Recombination Repair Genes

por Yap, Timothy A., Hamilton, Erika, Bauer, Todd, Dumbrava, Ecaterina E., Jeselsohn, Rinath, Enke, Aaron, Hurley, Sabrina, Lin, Kevin K., Habeck, Jenn, Giordano, Heidi, Shapiro, Geoffrey I.
Publicado 2022

A Quantitative Chemotherapy Genetic Interaction Map Reveals Factors Associated with PARP Inhibitor Resistance

por Hu, Hsien-Ming, Zhao, Xin, Kaushik, Swati, Robillard, Lilliane, Barthelet, Antoine, Lin, Kevin K., Shah, Khyati N., Simmons, Andy D., Raponi, Mitch, Harding, Thomas C., Bandyopadhyay, Sourav
Publicado 2018

Preclinical evaluation of FAP-2286 for fibroblast activation protein targeted radionuclide imaging and therapy

por Zboralski, Dirk, Hoehne, Aileen, Bredenbeck, Anne, Schumann, Anne, Nguyen, Minh, Schneider, Eberhard, Ungewiss, Jan, Paschke, Matthias, Haase, Christian, von Hacht, Jan L., Kwan, Tanya, Lin, Kevin K., Lenore, Jan, Harding, Thomas C., Xiao, Jim, Simmons, Andrew D., Mohan, Ajay-Mohan, Beindorff, Nicola, Reineke, Ulrich, Smerling, Christiane, Osterkamp, Frank
Publicado 2022

ATHENA (GOG-3020/ENGOT-ov45): a randomized, phase III trial to evaluate rucaparib as monotherapy (ATHENA–MONO) and rucaparib in combination with nivolumab (ATHENA–COMBO) as mainten...

por Monk, Bradley J, Coleman, Robert L, Fujiwara, Keiichi, Wilson, Michelle K, Oza, Amit M, Oaknin, Ana, O’Malley, David M, Lorusso, Domenica, Westin, Shannon N, Safra, Tamar, Herzog, Thomas J, Marmé, Frederik, N Eskander, Ramez, Lin, Kevin K, Shih, Danny, Goble, Sandra, Grechko, Nikolay, Hume, Stephanie, Maloney, Lara, McNeish, Iain A, Kristeleit, Rebecca S
Publicado 2021

Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma

por Kondrashova, Olga, Topp, Monique, Nesic, Ksenija, Lieschke, Elizabeth, Ho, Gwo-Yaw, Harrell, Maria I., Zapparoli, Giada V., Hadley, Alison, Holian, Robert, Boehm, Emma, Heong, Valerie, Sanij, Elaine, Pearson, Richard B., Krais, John J., Johnson, Neil, McNally, Orla, Ananda, Sumitra, Alsop, Kathryn, Hutt, Karla J., Kaufmann, Scott H., Lin, Kevin K., Harding, Thomas C., Traficante, Nadia, deFazio, Anna, McNeish, Iain A., Bowtell, David D., Swisher, Elizabeth M., Dobrovic, Alexander, Wakefield, Matthew J., Scott, Clare L.
Publicado 2018

Molecular and clinical determinants of response and resistance to rucaparib for recurrent ovarian cancer treatment in ARIEL2 (Parts 1 and 2)

por Swisher, Elizabeth M., Kwan, Tanya T., Oza, Amit M., Tinker, Anna V., Ray-Coquard, Isabelle, Oaknin, Ana, Coleman, Robert L., Aghajanian, Carol, Konecny, Gottfried E., O’Malley, David M., Leary, Alexandra, Provencher, Diane, Welch, Stephen, Chen, Lee-may, Wahner Hendrickson, Andrea E., Ma, Ling, Ghatage, Prafull, Kristeleit, Rebecca S., Dorigo, Oliver, Musafer, Ashan, Kaufmann, Scott H., Elvin, Julia A., Lin, Douglas I., Chambers, Setsuko K., Dominy, Erin, Vo, Lan-Thanh, Goble, Sandra, Maloney, Lara, Giordano, Heidi, Harding, Thomas, Dobrovic, Alexander, Scott, Clare L., Lin, Kevin K., McNeish, Iain A.
Publicado 2021

Characterization of a RAD51C-silenced high-grade serous ovarian cancer model during development of PARP inhibitor resistance

por Hurley, Rachel M, McGehee, Cordelia D, Nesic, Ksenija, Correia, Cristina, Weiskittel, Taylor M, Kelly, Rebecca L, Venkatachalam, Annapoorna, Hou, Xiaonan, Pathoulas, Nicholas M, Meng, X Wei, Kondrashova, Olga, Radke, Marc R, Schneider, Paula A, Flatten, Karen S, Peterson, Kevin L, Becker, Marc A, Wong, Ee Ming, Southey, Melissa S, Dobrovic, Alexander, Lin, Kevin K, Harding, Thomas C, McNeish, Iain, Ross, Christian A, Wagner, Jill M, Wakefield, Matthew J, Scott, Clare L, Haluska, Paul, Wahner Hendrickson, Andrea E, Karnitz, Larry M, Swisher, Elizabeth M, Li, Hu, Weroha, S John, Kaufmann, Scott H
Publicado 2021

A Randomized, Phase III Trial to Evaluate Rucaparib Monotherapy as Maintenance Treatment in Patients With Newly Diagnosed Ovarian Cancer (ATHENA–MONO/GOG-3020/ENGOT-ov45)

por Monk, Bradley J., Parkinson, Christine, Lim, Myong Cheol, O'Malley, David M., Oaknin, Ana, Wilson, Michelle K., Coleman, Robert L., Lorusso, Domenica, Bessette, Paul, Ghamande, Sharad, Christopoulou, Athina, Provencher, Diane, Prendergast, Emily, Demirkiran, Fuat, Mikheeva, Olga, Yeku, Oladapo, Chudecka-Glaz, Anita, Schenker, Michael, Littell, Ramey D., Safra, Tamar, Chou, Hung-Hsueh, Morgan, Mark A., Drochýtek, Vít, Barlin, Joyce N., Van Gorp, Toon, Ueland, Fred, Lindahl, Gabriel, Anderson, Charles, Collins, Dearbhaile C., Moore, Kathleen, Marme, Frederik, Westin, Shannon N., McNeish, Iain A., Shih, Danny, Lin, Kevin K., Goble, Sandra, Hume, Stephanie, Fujiwara, Keiichi, Kristeleit, Rebecca S.
Publicado 2022