A p53/TIAF1/WWOX triad exerts cancer suppression but may cause brain protein aggregation due to p53/WWOX functional antagonism

por Chou, Pei-Yi, Lin, Sing-Ru, Lee, Ming-Hui, Schultz, Lori, Sze, Chun-I, Chang, Nan-Shan
Publicado 2019

Zfra restores memory deficits in Alzheimer's disease triple-transgenic mice by blocking aggregation of TRAPPC6AΔ, SH3GLB2, tau, and amyloid β, and inflammatory NF-κB activation

por Lee, Ming-Hui, Shih, Yao-Hsiang, Lin, Sing-Ru, Chang, Jean-Yun, Lin, Yu-Hao, Sze, Chun-I, Kuo, Yu-Min, Chang, Nan-Shan
Publicado 2017

Complement C1q Activates Tumor Suppressor WWOX to Induce Apoptosis in Prostate Cancer Cells

por Hong, Qunying, Sze, Chun-I, Lin, Sing-Ru, Lee, Ming-Hui, He, Ruei-Yu, Schultz, Lori, Chang, Jean-Yun, Chen, Shean-Jen, Boackle, Robert J., Hsu, Li-Jin, Chang, Nan-Shan
Publicado 2009

Hyaluronan activates Hyal-2/WWOX/Smad4 signaling and causes bubbling cell death when the signaling complex is overexpressed

por Hsu, Li-Jin, Hong, Qunying, Chen, Shur-Tzu, Kuo, Hsiang-Lin, Schultz, Lori, Heath, John, Lin, Sing-Ru, Lee, Ming-Hui, Li, Dong-Zhang, Li, Zih-Ling, Cheng, Hui-Ching, Armand, Gerard, Chang, Nan-Shan
Publicado 2016

WWOX Possesses N-Terminal Cell Surface-Exposed Epitopes WWOX(7-21) and WWOX(7-11) for Signaling Cancer Growth Suppression and Prevention In Vivo

por Wang, Wan-Jen, Ho, Pei-Chuan, Nagarajan, Ganesan, Chen, Yu-An, Kuo, Hsiang-Ling, Subhan, Dudekula, Su, Wan-Pei, Chang, Jean-Yun, Lu, Chen-Yu, Chang, Katarina T., Lin, Sing-Ru, Lee, Ming-Hui, Chang, Nan-Shan
Publicado 2019

Trafficking protein particle complex 6A delta (TRAPPC6AΔ) is an extracellular plaque-forming protein in the brain

por Chang, Jean-Yun, Lee, Ming-Hui, Lin, Sing-Ru, Yang, Li-Yi, Sun, H. Sunny, Sze, Chun-I, Hong, Qunying, Lin, Yee-Shin, Chou, Ying-Tsen, Hsu, Li-Jin, Jan, Ming-Shiou, Gong, Cheng-Xin, Chang, Nan-Shan
Publicado 2015

Dramatic Co-Activation of WWOX/WOX1 with CREB and NF-κB in Delayed Loss of Small Dorsal Root Ganglion Neurons upon Sciatic Nerve Transection in Rats

por Li, Meng-Yen, Lai, Feng-Jie, Hsu, Li-Jin, Lo, Chen-Peng, Cheng, Ching-Li, Lin, Sing-Ru, Lee, Ming-Hui, Chang, Jean-Yun, Subhan, Dudekula, Tsai, Ming-Shu, Sze, Chun-I, Pugazhenthi, Subbiah, Chang, Nan-Shan, Chen, Shur-Tzu
Publicado 2009

Therapeutic Zfra4-10 or WWOX7-21 Peptide Induces Complex Formation of WWOX with Selective Protein Targets in Organs that Leads to Cancer Suppression and Spleen Cytotoxic Memory Z C...

por Su, Wan-Pei, Wang, Wan-Jen, Chang, Jean-Yun, Ho, Pei-Chuan, Liu, Tsung-Yun, Wen, Kuang-Yu, Kuo, Hsiang-Ling, Chen, Yu-Jie, Huang, Shenq-Shyang, Subhan, Dudekula, Chen, Yu-An, Lu, Chen-Yu, Wu, Chia-Yun, Lin, Sing-Ru, Lee, Ming-Hui, Chiang, Ming-Fu, Sze, Chun-I, Chang, Nan-Shan
Publicado 2020

Zfra activates memory Hyal-2+ CD3− CD19− spleen cells to block cancer growth, stemness, and metastasis in vivo

por Lee, Ming-Hui, Su, Wan-Pei, Wang, Wan-Jen, Lin, Sing-Ru, Lu, Chen-Yu, Chen, Yu-An, Chang, Jean-Yun, Huang, Shenq-Shyang, Chou, Pei-Yi, Ye, Siou-Ru, Chen, Szu-Jung, He, Huan, Liu, Ting-Hsiu, Chou, Ying-Tsen, Hsu, Li-Jin, Lai, Feng-Jie, Chen, Shean-Jen, Lee, Hoong-Chien, Kakhniashvili, David, Goodman, Steven R., Chang, Nan-Shan
Publicado 2015