Hedgehog pathway as a drug target: Smoothened inhibitors in development

por Lin, Tara L, Matsui, William
Publicado 2012

Acute Myeloid Leukemia: Focus on Novel Therapeutic Strategies

por Lin, Tara L., Levy, M. Yair
Publicado 2012

High-Risk Microgranular Acute Promyelocytic Leukemia with a Five-Way Complex Translocation Involving PML-RARA

por Powers, Benjamin, Persons, Diane, Rao, Deepthi, Woodroof, Janet, Lin, Tara L.
Publicado 2015

Bendamustine Associated with Irreversible Ascending Paralysis

por Alhafez, Ashraf, Aljitawi, Omar S., Lin, Tara L., Ganguly, Siddhartha, Abhyankar, Sunil, McGuirk, Joseph P.
Publicado 2013

Efficacy and safety of CPX-351 versus 7 + 3 chemotherapy by European LeukemiaNet 2017 risk subgroups in older adults with newly diagnosed, high-risk/secondary AML: post hoc analysi...

por Cortes, Jorge E., Lin, Tara L., Asubonteng, Kobby, Faderl, Stefan, Lancet, Jeffrey E., Prebet, Thomas
Publicado 2022

Quality-adjusted Time Without Symptoms of disease or Toxicity (Q-TWiST) analysis of CPX-351 versus 7 + 3 in older adults with newly diagnosed high-risk/secondary AML

por Cortes, Jorge E., Lin, Tara L., Uy, Geoffrey L., Ryan, Robert J., Faderl, Stefan, Lancet, Jeffrey E.
Publicado 2021

Spliceosome mutations are associated with clinical response in a phase 1b/2 study of the PLK1 inhibitor onvansertib in combination with decitabine in relapsed or refractory acute m...

por Croucher, Peter J P, Ridinger, Maya, Becker, Pamela S., Lin, Tara L., Silberman, Sandra L., Wang, Eunice S., Zeidan, Amer M.
Publicado 2023

A Phase 1B Clinical Study of Combretastatin A1 Diphosphate (OXi4503) and Cytarabine (ARA-C) in Combination (OXA) for Patients with Relapsed or Refractory Acute Myeloid Leukemia

por Uckun, Fatih M., Cogle, Christopher R., Lin, Tara L., Qazi, Sanjive, Trieu, Vuong N., Schiller, Gary, Watts, Justin M.
Publicado 2019

Rates of complete diagnostic testing for patients with acute myeloid leukemia

por Lin, Tara L, Williams, Travis, He, Jianghua, Aljitawi, Omar S, Ganguly, Siddhartha, Abhyankar, Sunil, Fleming, Allan, Male, Heather, McGuirk, Joseph P
Publicado 2015

Transplant outcomes after CPX-351 vs 7 + 3 in older adults with newly diagnosed high-risk and/or secondary AML

por Uy, Geoffrey L., Newell, Laura F., Lin, Tara L., Goldberg, Stuart L., Wieduwilt, Matthew J., Ryan, Robert J., Faderl, Stefan, Lancet, Jeffrey E.
Publicado 2022

A Clinical Phase 1B Study of the CD3xCD123 Bispecific Antibody APVO436 in Patients with Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

por Uckun, Fatih M., Lin, Tara L., Mims, Alice S., Patel, Prapti, Lee, Cynthia, Shahidzadeh, Anoush, Shami, Paul J., Cull, Elizabeth, Cogle, Christopher R., Watts, Justin
Publicado 2021

Risk, Characteristics and Biomarkers of Cytokine Release Syndrome in Patients with Relapsed/Refractory AML or MDS Treated with CD3xCD123 Bispecific Antibody APVO436

por Uckun, Fatih M., Watts, Justin, Mims, Alice S., Patel, Prapti, Wang, Eunice, Shami, Paul J., Cull, Elizabeth, Lee, Cynthia, Cogle, Christopher R., Lin, Tara L.
Publicado 2021

Post-hoc Analysis of Pharmacodynamics and Single-Agent Activity of CD3xCD123 Bispecific Antibody APVO436 in Relapsed/Refractory AML and MDS Resistant to HMA or Venetoclax Plus HMA

por Watts, Justin, Lin, Tara L., Mims, Alice, Patel, Prapti, Lee, Cynthia, Shahidzadeh, Anoush, Shami, Paul, Cull, Elizabeth, Cogle, Christopher R., Wang, Eunice, Uckun, Fatih M.
Publicado 2022

Self-Renewal of Acute Lymphocytic Leukemia Cells Is Limited by the Hedgehog Pathway Inhibitors Cyclopamine and IPI-926

por Lin, Tara L., Wang, Qiuju H., Brown, Patrick, Peacock, Craig, Merchant, Akil A., Brennan, Sarah, Jones, Evan, McGovern, Karen, Watkins, D. Neil, Sakamoto, Kathleen M., Matsui, William
Publicado 2010

Atezolizumab alone or in combination did not demonstrate a favorable risk-benefit profile in myelodysplastic syndrome

por Gerds, Aaron T., Scott, Bart L., Greenberg, Peter, Lin, Tara L., Pollyea, Daniel A., Verma, Amit, Dail, Monique, Feng, Yuning, Green, Cherie, Ma, Connie, Medeiros, Bruno C., Yan, Mark, Yousefi, Kasra, Donnellan, William
Publicado 2022

A phase 2 study to assess the pharmacokinetics and pharmacodynamics of CPX-351 and its effects on cardiac repolarization in patients with acute leukemias

por Lin, Tara L., Newell, Laura F., Stuart, Robert K., Michaelis, Laura C., Rubenstein, Eric, Pentikis, Helen S., Callahan, Timothy, Alvarez, Donna, Liboiron, Barry D., Mayer, Lawrence D., Wang, Qi, Banerjee, Kamalika, Louie, Arthur C.
Publicado 2019

Quantifying the impact of the COVID-19 pandemic on cancer center clinical trial operations

por George, Thomas J, Lin, Tara L, Adrales Bentz, Tricia, Grant, Stefan, Houston, Collette M, Nashawati, Melissa A, Pappu, Bhanu, Peck, Helen, Zafirovski, Alex, Kerstann, Kimberly, LoRusso, Patricia, Schnatterly, Anne, Hofacker, Janie, Cameron, Kendra, Honeycutt, Hailey, Werner, Theresa L
Publicado 2023

Functional characterization of NPM1–TYK2 fusion oncogene

por Kuravi, Sudhakiranmayi, Baker, Riley W., Mushtaq, Muhammad Umair, Saadi, Irfan, Lin, Tara L., Vivian, Carolyn J., Valluripalli, Anusha, Abhyankar, Sunil, Ganguly, Siddhartha, Cui, Wei, Elenitoba-Johnson, Kojo S. J., Welch, Danny R., Jensen, Roy A., Saunthararajah, Yogen, McGuirk, Joseph P., Balusu, Ramesh
Publicado 2022

Venetoclax Combined With Low-Dose Cytarabine for Previously Untreated Patients With Acute Myeloid Leukemia: Results From a Phase Ib/II Study

por Wei, Andrew H., Strickland, Stephen A., Hou, Jing-Zhou, Fiedler, Walter, Lin, Tara L., Walter, Roland B., Enjeti, Anoop, Tiong, Ing Soo, Savona, Michael, Lee, Sangmin, Chyla, Brenda, Popovic, Relja, Salem, Ahmed Hamed, Agarwal, Suresh, Xu, Tu, Fakouhi, Kaffa M., Humerickhouse, Rod, Hong, Wan-Jen, Hayslip, John, Roboz, Gail J.
Publicado 2019

CPX-351 (cytarabine and daunorubicin) Liposome for Injection Versus Conventional Cytarabine Plus Daunorubicin in Older Patients With Newly Diagnosed Secondary Acute Myeloid Leukemi...

por Lancet, Jeffrey E., Uy, Geoffrey L., Cortes, Jorge E., Newell, Laura F., Lin, Tara L., Ritchie, Ellen K., Stuart, Robert K., Strickland, Stephen A., Hogge, Donna, Solomon, Scott R., Stone, Richard M., Bixby, Dale L., Kolitz, Jonathan E., Schiller, Gary J., Wieduwilt, Matthew J., Ryan, Daniel H., Hoering, Antje, Banerjee, Kamalika, Chiarella, Michael, Louie, Arthur C., Medeiros, Bruno C.
Publicado 2018