Temporal and structural evolution of the Early Palæogene rocks of the Seychelles microcontinent

por Shellnutt, J. Gregory, Yeh, Meng-Wan, Suga, Kenshi, Lee, Tung-Yi, Lee, Hao-Yang, Lin, Te-Hsien
Publicado 2017

Neuroprotective Action of Coumarin Derivatives through Activation of TRKB-CREB-BDNF Pathway and Reduction of Caspase Activity in Neuronal Cells Expressing Pro-Aggregated Tau Protei...

por Lin, Te-Hsien, Chang, Kuo-Hsuan, Chiu, Ya-Jen, Weng, Zheng-Kui, Sun, Ying-Chieh, Lin, Wenwei, Lee-Chen, Guey-Jen, Chen, Chiung-Mei
Publicado 2022

Formulated Chinese Medicine Shaoyao Gancao Tang Reduces Tau Aggregation and Exerts Neuroprotection through Anti-Oxidation and Anti-Inflammation

por Chen, I-Cheng, Lin, Te-Hsien, Hsieh, Yu-Hsuan, Chao, Chih-Ying, Wu, Yih-Ru, Chang, Kuo-Hsuan, Lee, Ming-Chung, Lee-Chen, Guey-Jen, Chen, Chiung-Mei
Publicado 2018

Novel TRKB agonists activate TRKB and downstream ERK and AKT signaling to protect Aβ-GFP SH-SY5Y cells against Aβ toxicity

por Chiu, Ya-Jen, Lin, Te-Hsien, Chang, Kuo-Hsuan, Lin, Wenwei, Hsieh-Li, Hsiu Mei, Su, Ming-Tsan, Chen, Chiung-Mei, Sun, Ying-Chieh, Lee-Chen, Guey-Jen
Publicado 2022

New Synthetic 3-Benzoyl-5-Hydroxy-2H-Chromen-2-One (LM-031) Inhibits Polyglutamine Aggregation and Promotes Neurite Outgrowth through Enhancement of CREB, NRF2, and Reduction of AM...

por Chen, Chiung-Mei, Chen, Wan-Ling, Yang, Shu-Ting, Lin, Te-Hsien, Yang, Shu-Mei, Lin, Wenwei, Chao, Chih-Ying, Wu, Yih-Ru, Chang, Kuo-Hsuan, Lee-Chen, Guey-Jen
Publicado 2020

Using ΔK280 Tau(RD) Folding Reporter Cells to Screen TRKB Agonists as Alzheimer’s Disease Treatment Strategy

por Weng, Zheng-Kui, Lin, Te-Hsien, Chang, Kuo-Hsuan, Chiu, Ya-Jen, Lin, Chih-Hsin, Tseng, Pei-Hsuan, Sun, Ying-Chieh, Lin, Wenwei, Lee-Chen, Guey-Jen, Chen, Chiung-Mei
Publicado 2023

Pathomechanism characterization and potential therapeutics identification for SCA3 targeting neuroinflammation

por Chiu, Ya-Jen, Lin, Shu-An, Chen, Wan-Ling, Lin, Te-Hsien, Lin, Chih-Hsin, Yao, Ching-Fa, Lin, Wenwei, Wu, Yih-Ru, Chang, Kuo-Hsuan, Lee-Chen, Guey-Jen, Chen, Chiung-Mei
Publicado 2020

Flavones 7,8-DHF, Quercetin, and Apigenin Against Tau Toxicity via Activation of TRKB Signaling in ΔK280 Tau(RD)-DsRed SH-SY5Y Cells

por Chiang, Ni-Ni, Lin, Te-Hsien, Teng, Yu-Shan, Sun, Ying-Chieh, Chang, Kuo-Hsuan, Lin, Chung-Yin, Hsieh-Li, Hsiu Mei, Su, Ming-Tsan, Chen, Chiung-Mei, Lee-Chen, Guey-Jen
Publicado 2021

Aqueous Extract of Paeonia lactiflora and Paeoniflorin as Aggregation Reducers Targeting Chaperones in Cell Models of Spinocerebellar Ataxia 3

por Chang, Kuo-Hsuan, Chen, Wan-Ling, Lee, Li-Ching, Lin, Chih-Hsin, Kung, Pin-Jui, Lin, Te-Hsien, Wu, Yi-Ci, Wu, Yih-Ru, Chen, Yi-Chun, Lee-Chen, Guey-Jen, Chen, Chiung-Mei
Publicado 2013

The aqueous extract of Glycyrrhiza inflata can upregulate unfolded protein response-mediated chaperones to reduce tau misfolding in cell models of Alzheimer’s disease

por Chang, Kuo-Hsuan, Chen, I-Cheng, Lin, Hsuan-Yuan, Chen, Hsuan-Chiang, Lin, Chih-Hsin, Lin, Te-Hsien, Weng, Yu-Ting, Chao, Chih-Ying, Wu, Yih-Ru, Lin, Jung-Yaw, Lee-Chen, Guey-Jen, Chen, Chiung-Mei
Publicado 2016

Novel Synthetic Coumarin-Chalcone Derivative (E)-3-(3-(4-(Dimethylamino)Phenyl)Acryloyl)-4-Hydroxy-2H-Chromen-2-One Activates CREB-Mediated Neuroprotection in Aβ and Tau Cell Model...

por Chiu, Ya-Jen, Lin, Te-Hsien, Chen, Chiung-Mei, Lin, Chih-Hsin, Teng, Yu-Shan, Lin, Chung-Yin, Sun, Ying-Chieh, Hsieh-Li, Hsiu Mei, Su, Ming-Tsan, Lee-Chen, Guey-Jen, Lin, Wenwei, Chang, Kuo-Hsuan
Publicado 2021

Shaoyao Gancao Tang (SG-Tang), a formulated Chinese medicine, reduces aggregation and exerts neuroprotection in spinocerebellar ataxia type 17 (SCA17) cell and mouse models

por Chen, Chiung-Mei, Chen, Wan-Ling, Hung, Chen-Ting, Lin, Te-Hsien, Lee, Ming-Chung, Chen, I-Cheng, Lin, Chih-Hsin, Chao, Chih-Ying, Wu, Yih-Ru, Chang, Kuo-Hsuan, Hsieh-Li, Hsiu Mei, Lee-Chen, Guey-Jen
Publicado 2019

Indole and synthetic derivative activate chaperone expression to reduce polyQ aggregation in SCA17 neuronal cell and slice culture models

por Kung, Pin-Jui, Tao, Yu-Chen, Hsu, Ho-Chiang, Chen, Wan-Ling, Lin, Te-Hsien, Janreddy, Donala, Yao, Ching-Fa, Chang, Kuo-Hsuan, Lin, Jung-Yaw, Su, Ming-Tsan, Wu, Chung-Hsin, Lee-Chen, Guey-Jen, Hsieh-Li, Hsiu-Mei
Publicado 2014

Exploration of multi‐target effects of 3‐benzoyl‐5‐hydroxychromen‐2‐one in Alzheimer’s disease cell and mouse models

por Lin, Te‐Hsien, Chiu, Ya‐Jen, Lin, Chih‐Hsin, Lin, Chung‐Yin, Chao, Chih‐Ying, Chen, Yu‐Chieh, Yang, Shu‐Mei, Lin, Wenwei, Mei Hsieh‐Li, Hsiu, Wu, Yih‐Ru, Chang, Kuo‐Hsuan, Lee‐Chen, Guey‐Jen, Chen, Chiung‐Mei
Publicado 2020

Virtual Screening and Testing of GSK-3 Inhibitors Using Human SH-SY5Y Cells Expressing Tau Folding Reporter and Mouse Hippocampal Primary Culture under Tau Cytotoxicity

por Lin, Chih-Hsin, Hsieh, Yu-Shao, Sun, Ying-Chieh, Huang, Wun-Han, Chen, Shu-Ling, Weng, Zheng-Kui, Lin, Te-Hsien, Wu, Yih-Ru, Chang, Kuo-Hsuan, Huang, Hei-Jen, Lee, Guan-Chiun, Hsieh-Li, Hsiu Mei, Lee-Chen, Guey-Jen
Publicado 2023